Protein Alignment exex and vab-15

DIOPT Version :10

• Sequence 1: NP_648164.1
• Gene: exex / 38884
• FlyBaseID: FBgn0041156
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_509648.1
• Gene: vab-15 / 181197
• WormBaseID: WBGene00006881
• Length: 225
• Species: Caenorhabditis elegans
• Alignment Length: 662
• Identity: 129/662 - (19%)
• Similarity: 203/662 - (30%)
• Gaps: 264/662 - (39%)

  Fly     1 MNKLVVEIVDASDLMPKDGQGSASPFVEVEFDEQRQRTQTRFKDLNPQWNEKL--------VFNV 57
            |:.|:.||:.:.:.:.|....:..|:|:                  |..|..|        :.|.
 Worm     1 MSLLLEEIIRSVEALLKLRNRNQEPYVD------------------PNLNPVLLVPGIAGSILNA 47

  Fly    58 GDLKRLNNKTVDVTVYD----------DRRDNQPGKFLGRVKIAGAVVPLSESESGVQRYPLDKR 112
            .|.:..|.:.|.|.::.          .|.|...||.:........||            |.|:.
 Worm    48 VDHENGNEERVWVRIFGADHEFRTKMWSRFDPSTGKTISLDPKTSIVV------------PQDRA 100

  Fly   113 GLFSNIKGDIALRIYAAPIDGGDFVSPPPD----------FAEKVM-------KEDKRFESQEFQ 160
            ||.:              ||..|     ||          |.|.::       :|.|......:.
 Worm   101 GLHA--------------IDVLD-----PDMIVGRESVYYFHEMIVEMIGWGFEEGKTLFGFGYD 146

  Fly   161 FQNQNQNQNHYEQFEDEINNMETLKPTKKKEKESRTFHSIGA---------HAGGGGGAPPMSQA 216
            |:..|:.|...:||   ...:||:.....::|.:...||:|.         |          |..
 Worm   147 FRQSNRLQETLDQF---AKKLETVYKASGEKKINVISHSMGGLLVKCFMGLH----------SDI 198

  Fly   217 KQAYPPPPNQPEFRSDFMRAPGPPTGAV---MQMQPPRQQN------PEFQLIETSPPLAARMRQ 272
            .:.|  ..|.....:.|..|||..|..:   |......:||      ...||:...|.:...|..
 Worm   199 FEKY--VQNWIAIAAPFRGAPGYITSTLLNGMSFVNGWEQNFFVSKWSMHQLLIECPSIYELMCC 261

  Fly   273 SYY------------YRSSGDKTSSTYDLVEQMHYLYVSVV------------------KARDLP 307
            .|:            .:.|.|...::|.::|.    |.|:.                  ::.|||
 Worm   262 PYFKWELPPVLELWREKESNDGVGTSYVVLES----YCSLESLEVFTKSLSNNTADYCGESIDLP 322

  Fly   308 ----VMD---------VSGSLDPYVEVKLGNYKGL---TKHLEKNSNPIWKQIFAFSKERLQSNL 356
                :|:         .|..|.|  :||..|..|.   |.|           ...:..|::
 Worm   323 FNWKIMEWAHKTKQVLASAKLPP--KVKFYNIYGTNLETPH-----------SVCYGNEKM---- 370

  Fly   357 LEVTVKDKDLLTKDDFVGRVHI----DLTEVPLRVPPDSPLA-----------PQWYR--LEDKK 404
               .|||   ||...:....:|    |.|     ||.:|.:|           |..:|  |.|.:
 Worm   371 ---PVKD---LTNLRYFQPTYICVDGDGT-----VPMESAMADGLEAVARVGVPGEHRGILNDHR 424

  Fly   405 GMKTNRGEIMLAVWMGTQADESFPDAWHSDAHRVSHSNLSNTRSKVYFSPKLY-YLRIH------ 462
            ..:      ||..|:..    ..||.::            |..:.....|..| :.:.|
 Worm   425 VFR------MLKKWLNV----GEPDPFY------------NPVNDYVILPTTYEFEKFHENGLEV 467

  Fly   463 --VMEAQDLVPSDK-----GRVPDAIVKIQAGN------QMRATRTPQMRTMNPQWHEELMFVVS 514
              |.|:.|::..|.     |...::|...|.|:      :.|||.|.|.::...| |.||
 Worm   468 ASVKESWDIISDDNNIGTTGSTVNSISVSQPGDDQNPQAEARATLTVQPQSDGRQ-HVEL----- 526

  Fly   515 EPFEDMVIVSVD 526
                :.|.||||
 Worm   527 ----NAVSVSVD 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
exex	NP_648164.1	Homeodomain	440..496	CDD:459649	15/75 (20%)
vab-15	NP_509648.1	Homeodomain	130..186	CDD:459649	13/58 (22%)