Protein Alignment exex and GSX2

DIOPT Version :9

• Sequence 1: NP_648164.1
• Gene: exex / 38884
• FlyBaseID: FBgn0041156
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_573574.2
• Gene: GSX2 / 170825
• HGNCID: 24959
• Length: 304
• Species: Homo sapiens
• Alignment Length: 386
• Identity: 97/386 - (25%)
• Similarity: 120/386 - (31%)
• Gaps: 169/386 - (43%)

  Fly   148 PPHHVPHPHPA------LGTYPLPRLPLMLPANPPGVPSGAAAPPPVSPQPAANHLSHS------ 200
            |...:|.|||.      ||..|    ||::..:.||.||..:....|.|....:||..|
Human    18 PAPSLPEPHPGPDFFIPLGMPP----PLVMSVSGPGCPSRKSGAFCVCPLCVTSHLHSSRGSVGA 78

  Fly   201 ------------------GATMATTTLLPPAQSQP-KKSFCIDALLAKSQHQSGEPQPIIVDDRL 246
                              ||..|...|.....|.| ...||  ..:..:.|....||
Human    79 GSGGAGAGVTGAGGSGVAGAAGALPLLKGQFSSAPGDAQFC--PRVNHAHHHHHPPQ-------- 133

  Fly   247 AALHYARDQAELNHAFVTASNAAAAAQAAASAAGGISEQEALQRIRDSREYDSPSPDGMSRSESP 311
               |:.............|:.|||||.|||:|.|
Human   134 ---HHHHHHQPQQPGSAAAAAAAAAAAAAAAALG------------------------------- 164

  Fly   312 TSSHRSSPPISPGCEDQQQPHGALHPQHLSMRMSDFHDEFKKPIPPHSPIRPQDFPLYAGGHPYQ 376
                                    ||||                  |:|:........|....:.
Human   165 ------------------------HPQH------------------HAPVCTATTYNVADPRRFH 187

  Fly   377 LLAQGGSAFHRPLDPSGKPIPIPMGHNFMPSQLQFEFLARAGMLHHRIPELAAYPHHAILGKTRR 441
            .|..|||      |.|    .:|.|                                      :|
Human   188 CLTMGGS------DAS----QVPNG--------------------------------------KR 204

  Fly   442 PRTAFTSQQLLELEKQFKQNKYLSRPKRFEVASGLMLSETQVKIWFQNRRMKWKRSKKAQQ 502
            .||||||.||||||::|..|.||||.:|.|:|:.|.|||.||||||||||:|.|:..|..|
Human   205 MRTAFTSTQLLELEREFSSNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKGTQ 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
exex	NP_648164.1	Homeobox	442..495	CDD:278475	36/52 (69%)
GSX2	NP_573574.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	116..151		7/47 (15%)
		Homeobox	206..258	CDD:306543	36/51 (71%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	283..304

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810