DRSC/TRiP Functional Genomics Resources

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Protein Alignment exex and Hoxa3

DIOPT Version :9

Sequence 1:NP_648164.1 Gene:exex / 38884 FlyBaseID:FBgn0041156 Length:525 Species:Drosophila melanogaster
Sequence 2:NP_034582.1 Gene:Hoxa3 / 15400 MGIID:96175 Length:443 Species:Mus musculus


Alignment Length:443 Identity:100/443 - (22%)
Similarity:132/443 - (29%) Gaps:226/443 - (51%)


- Green bases have known domain annotations that are detailed below.


  Fly    68 SQITPSPPAASPTHSAATTGSPVSTYTPALSPGG-------AQDSSQTESGQSSQMPLLVAPMPV 125
            ||...:|.||..|..........|..:|| |.||       ::...:|.||..||        |.
Mouse    29 SQQPYAPSAALGTDGVEYHRPACSLQSPA-SAGGHPKTHELSEACLRTLSGPPSQ--------PP 84

  Fly   126 GTGPPHSHPPPPHPRLYVEGFPPPHHVPHPHPALGTYPLPRLPLMLPANPPGVPSGAAAPPP--V 188
            |.|.|...||||      :..||....|.|                |..|| .|:.||.|||  |
Mouse    85 GLGEPPLPPPPP------QAAPPAPQPPQP----------------PPQPP-APTPAAPPPPSSV 126

  Fly   189 SPQPAANHLSHSGATMATTTLLPPAQSQPKKSFCIDALLAKSQHQSGEPQPIIVDDRLAALHYAR 253
            ||..:||    |..|.|:|                    |||        |:             
Mouse   127 SPPQSAN----SNPTPAST--------------------AKS--------PL------------- 146

  Fly   254 DQAELNHAFVTASNAAAAAQAAASAAGGISEQEALQRIRDSREYDSPSPDGMSRSESPTSSHRSS 318
                ||...|                    .::....:::||:.......|.|..||        
Mouse   147 ----LNSPTV--------------------GKQIFPWMKESRQNTKQKTSGSSSGES-------- 179

  Fly   319 PPISPGCEDQQQPHGALHPQHLSMRMSDFHDEFKKPIPPHSPIRPQDFPLYAGGHPYQLLAQGGS 383
                  |...:.|.|.                                                 
Mouse   180 ------CAGDKSPPGQ------------------------------------------------- 189

  Fly   384 AFHRPLDPSGKPIPIPMGHNFMPSQLQFEFLARAGMLHHRIPELAAYPHHAILGKTRRPRTAFTS 448
                                                                 ..::|.|||:||
Mouse   190 -----------------------------------------------------ASSKRARTAYTS 201

  Fly   449 QQLLELEKQFKQNKYLSRPKRFEVASGLMLSETQVKIWFQNRRMKWKRSKKAQ 501
            .||:||||:|..|:||.||:|.|:|:.|.|:|.|:||||||||||:|:.:|.:
Mouse   202 AQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGK 254

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
exexNP_648164.1 Homeobox 442..495 CDD:278475 34/52 (65%)
Hoxa3NP_034582.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 74..151 41/156 (26%)
Antp-type hexapeptide 156..161 0/4 (0%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 163..197 10/149 (7%)
COG5576 <182..309 CDD:227863 39/175 (22%)
Homeobox 196..249 CDD:365835 34/52 (65%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 248..354 2/7 (29%)
DUF4074 378..441 CDD:372548
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 401..443
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0489
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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