DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment exex and Hoxb2

DIOPT Version :9

Sequence 1:	NP_648164.1	Gene:	exex / 38884	FlyBaseID:	FBgn0041156	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_598793.2	Gene:	Hoxb2 / 103889	MGIID:	96183	Length:	354	Species:	Mus musculus

Alignment Length:	190	Identity:	67/190 - (35%)
Similarity:	84/190 - (44%)	Gaps:	43/190 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   355 IPPHSPIRPQDFP-LYAGGHPYQLLAQGGSAFHRPLDPSGKPIPI-PMGHNF----------MPS 407
            |||..|:. |.|| |..|....|.......|...|...|..|:|: |....|          .||
Mouse    43 IPPPPPLE-QTFPSLQLGASTLQRPGSQKQAGDGPALRSPPPLPVAPPAPEFPWMKEKKSTKKPS 106

  Fly   408 QLQFEFLARAGMLHHR----------IPELAAYPHHAILGKTRRPRTAFTSQQLLELEKQFKQNK 462
            |........|..:...          :||...       ..:||.|||:|:.|||||||:|..||
Mouse   107 QSAASPSPAASSVRASEVGSPSDGPGLPECGG-------SGSRRLRTAYTNTQLLELEKEFHFNK 164

  Fly   463 YLSRPKRFEVASGLMLSETQVKIWFQNRRMKWKRSKK-------------AQQEAKERAK 509
            ||.||:|.|:|:.|.|:|.|||:||||||||.||..:             ||.:|.|.|:
Mouse   165 YLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQHREPPEGEPGGPSAQDDAGEPAE 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
exex	NP_648164.1	Homeobox	442..495	CDD:278475	35/52 (67%)
Hoxb2	NP_598793.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	39..143		23/107 (21%)
		Antp-type hexapeptide	92..97		1/4 (25%)
		Homeobox	145..197	CDD:278475	35/51 (69%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	193..231		10/32 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	246..295
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810