DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment exex and hoxc3

DIOPT Version :9

Sequence 1:	NP_648164.1	Gene:	exex / 38884	FlyBaseID:	FBgn0041156	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	XP_002936696.1	Gene:	hoxc3 / 100190990	XenbaseID:	XB-GENE-5997986	Length:	394	Species:	Xenopus tropicalis

Alignment Length:	244	Identity:	68/244 - (27%)
Similarity:	103/244 - (42%)	Gaps:	77/244 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   266 SNAAAAAQAAASAAG------GISEQEALQRIRDSREYDSPSPDGMSRSESPTSSHRSSPPISPG 324
            :|.:|:.:...|..|      .:|||....:..:|   |||.|...| ::|.||...:.|..|..
Frog    51 ANGSASHKGEHSIKGIDFHLSEVSEQAQQPKSPNS---DSPLPKSAS-TQSCTSKKSTGPVSSDV 111

  Fly   325 CEDQQQPHGALHPQHLS--MRMSDFHDEFKKPIPPHSPIRPQDFPLYAGGHPYQLLAQGGSAFHR 387
            ....::..|:..|:.:.  |:.:..:.:.||..||.:...|
Frog   112 TSPNKKSKGSNMPKQIFPWMKETRQNSKQKKQAPPPADDAP------------------------ 152

  Fly   388 PLDPSGKPIPIPMGHNFMPSQLQFEFLARAGMLHHRIPELAAYPHHAILGKTRRPRTAFTSQQLL 452
            .:|.|                    ||:.|                     ::|.|||:|:.||:
Frog   153 AVDSS--------------------FLSSA---------------------SKRARTAYTNSQLV 176

  Fly   453 ELEKQFKQNKYLSRPKRFEVASGLMLSETQVKIWFQNRRMKWKRSKKAQ 501
            ||||:|..|:||.||:|.|:|..|.|||.|:||||||||||:|:..|.:
Frog   177 ELEKEFHFNRYLCRPRRLEMAKLLNLSERQIKIWFQNRRMKFKKDHKGK 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
exex	NP_648164.1	Homeobox	442..495	CDD:278475	34/52 (65%)
hoxc3	XP_002936696.1	Homeobox	167..220	CDD:395001	34/52 (65%)
hoxc3	XP_002936696.1	DUF4074	335..392	CDD:404218
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910