Protein Alignment pbl and rad4

DIOPT Version :9

• Sequence 1: NP_523965.2
• Gene: pbl / 38879
• FlyBaseID: FBgn0003041
• Length: 1311
• Species: Drosophila melanogaster
• Sequence 2: NP_593190.1
• Gene: rad4 / 2543281
• PomBaseID: SPAC23C4.18c
• Length: 648
• Species: Schizosaccharomyces pombe
• Alignment Length: 651
• Identity: 129/651 - (19%)
• Similarity: 222/651 - (34%)
• Gaps: 204/651 - (31%)

  Fly   120 CFTGIRKKDELTKLVNLIHSMGGCIKKDLNTKTTHLICNHSGGEKYQYAKTFRLTVVRPAWVFAA 184
            |.|.| .:.|.:::.|.:...||....||....||||...|.|.||:||..:::.||...|::.:
pombe   108 CLTNI-GQPERSRIENYVLKHGGTFCPDLTRDVTHLIAGTSSGRKYEYALKWKINVVCVEWLWQS 171

  Fly   185 WADRNSLEFDATQENFTKTHRLKAFEGQKICFFGFPVEEHQHMVDVLLENGGVCA--ELDDPECS 247
             ..||::                             :|.....:|:..|..|:.|  .||
pombe   172 -IQRNAV-----------------------------LEPQYFQLDMPAEKIGLGAYVRLD----- 201

  Fly   248 HVVMPNTGAVFTSTSTSTDTNPSTLINPPESQVPGSSSASQAGEEEQRKAEHLEQAEIKKMEYSH 312
                ||     |:.:.|...|.....|..:|   |.|.|:.|.|.:      ||...:|:
pombe   202 ----PN-----TTEAKSYSENQKISKNKEKS---GQSLAALAEEAD------LEPVIMKR----- 243

  Fly   313 AETDNGMSLDIDQEQKENQGIEDEDDIHFDERLFVEAADIINHGEDQLPESDEED--LEEEQKPK 375
                               |.:.:..|.::|         :|:|:.:.....||:  |.::..|:
pombe   244 -------------------GKKRDRSILWEE---------LNNGKFEFSSRSEENSVLLDDFTPE 280

  Fly   376 VEEVLKEQEVEEDV-----------------QASTPKTSKIRTSLKAATPLSSPEMDGIALDFES 423
            ..:.|:|.|::.::                 :....|.|::...|.        :..|...:|.|
pombe   281 TVQPLEENELDTELNIENEAKLFKNLTFYLYEFPNTKVSRLHKCLS--------DNGGQISEFLS 337

  Fly   424 TTQN--ISPILKAIDECDLETDDLP----PSENDLKRKRESFDNVSLMSVDSFALPASTKKPKLI 482
            :|.:  :.|....:||       ||    |:.|:...:|..:.. .:..:|..||.....:|.|:
pombe   338 STIDFVVIPHYFPVDE-------LPIFSFPTVNEWWIERCLYYK-KIFGIDEHALAKPFFRPSLV 394

  Fly   483 R--TG-SISRTLRRSVSFVAEPLMKTLRPRRSSVADASSFVGSEAADNSICSLASSINLTLNDSI 544
            .  .| ||..|     .|..|.|        |.:..|.:.:|  |..:....:..||.|.   :.
pombe   395 PYFNGLSIHLT-----GFKGEEL--------SHLKKALTILG--AVVHEFLGVQRSILLV---NT 441

  Fly   545 RKPVKEKLRSFCGRITRSSSRRHDRGVDGTPECTTLLDSG-FKTPKAPKLRSTATPKTAKRLFGP 608
            .:|...|.|......|..:.|     |.|......::.|| |....:|........:..|:.
pombe   442 NEPFSMKTRFKIQHATEWNVR-----VVGVAWLWNIIQSGKFIDQVSPWAIDKKENQEIKKF--- 498

  Fly   609 VSGVVSALTLTNPSTPTPNPNPNTNCTATLDVNDTSIHTFAFCAAAVTPAMPPSSSSSSSSPIL- 672
                               .|.|.....|.| .||.:..       .....|...|:..:||.|
pombe   499 -------------------TNQNNMVFPTSD-RDTRLQN-------SLAQQPIGHSTPHNSPSLL 536

  Fly   673 ------STSIAVHSSVQVIKSPEEST--TRRNSPAPIEEPMAMVVDE--HTTLTKPE-PKNNHTH 726
                  :..|..::.:|:..:.::||  .||:...|.::     :|.  .:::|||| |.:...|
pombe   537 SVKKRQNNHIRSNTLIQLNSNSKDSTIFPRRSVTVPGDK-----IDTVWKSSVTKPETPTSPQEH 596

  Fly   727 I 727
            :
pombe   597 V 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pbl	NP_523965.2	PTCB-BRCT	117..180	CDD:289507	21/59 (36%)
		RhoGEF	852..1032	CDD:279015
		PH_Ect2	1023..1186	CDD:269936
rad4	NP_593190.1	BRCT	4..75	CDD:214602
		PTCB-BRCT	105..167	CDD:289507	21/59 (36%)
		BRCT	301..371	CDD:214602	15/84 (18%)
		BRCT	395..473	CDD:278934	21/100 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	42	1.000	Domainoid score	I3668
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm47399
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000