Protein Alignment eIF4E5 and eIF4E1

DIOPT Version :10

• Sequence 1: NP_648160.2
• Gene: eIF4E5 / 38878
• FlyBaseID: FBgn0035823
• Length: 232
• Species: Drosophila melanogaster
• Sequence 2: NP_524829.1
• Gene: eIF4E1 / 45525
• FlyBaseID: FBgn0015218
• Length: 259
• Species: Drosophila melanogaster
• Alignment Length: 236
• Identity: 127/236 - (53%)
• Similarity: 171/236 - (72%)
• Gaps: 17/236 - (7%)

  Fly     2 ASAQVQSFDIMKQQDQQHQLNSIHKHHHHHEGVPL--ESNSPEPIDEEIYQVE--YKHPLEHVWT 62
            |:|..::.|:..::|.|            ..|.|.  .:.:..|..::..:.|  |||||.:|||
  Fly    36 AAAPAEAKDVKPKEDPQ------------ETGEPAGNTATTTAPAGDDAVRTEHLYKHPLMNVWT 88

  Fly    63 LWYLENDRTKHWKDMLNEITEIDSVETFWSLYHTIKTPAELKIGCDYSVFKKGIKPMWEDEANIK 127
            ||||||||:|.|:||.||||..|:||.|||||:.||.|:|:|:|.|||:|||.|:|||||.||.:
  Fly    89 LWYLENDRSKSWEDMQNEITSFDTVEDFWSLYNHIKPPSEIKLGSDYSLFKKNIRPMWEDAANKQ 153

  Fly   128 GGRWLVTVSKSAKAELDQIWLDILLLMVGQNFEYSDEICGAVINIRNKSNKISVWTANGSNEMAI 192
            ||||::|::||:|.:||.:|||:||.::|:.|::||:|||||||||.||||||:|||:|:||.|.
  Fly   154 GGRWVITLNKSSKTDLDNLWLDVLLCLIGEAFDHSDQICGAVINIRGKSNKISIWTADGNNEEAA 218

  Fly   193 LEIGQKLKILLHL-QSHSLQYQLHSDAMSKFNSGVKSVYTL 232
            ||||.||:..|.| :::|||||||.|.|.|..|.|||:|||
  Fly   219 LEIGHKLRDALRLGRNNSLQYQLHKDTMVKQGSNVKSIYTL 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4E5	NP_648160.2	IF4E	56..212	CDD:460281	100/156 (64%)
eIF4E1	NP_524829.1	IF4E	82..239	CDD:460281	100/156 (64%)