DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment eIF4E5 and ife-1

DIOPT Version :9

Sequence 1:	NP_648160.2	Gene:	eIF4E5 / 38878	FlyBaseID:	FBgn0035823	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_001255196.1	Gene:	ife-1 / 176755	WormBaseID:	WBGene00002059	Length:	231	Species:	Caenorhabditis elegans

Alignment Length:	211	Identity:	77/211 - (36%)
Similarity:	119/211 - (56%)	Gaps:	20/211 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 EGVPLESNSPEPIDEEIYQVEYKHPLEHVWTLWYLENDRTKHWKDMLNEITEIDSVETFWSLYHT 96
            ||:.....:..||          :||:..||.|||.::|.|.|:|.|.::...::|..||:||..
Worm    18 EGMTETEQTTAPI----------YPLKRNWTWWYLNDERNKSWEDRLKKVYTFNTVSEFWALYDA 72

  Fly    97 IKTPAELKIGCDYSVFKKGIKPMWEDEANIKGGRWLVTVSKSAKAEL-DQIWLDILLLMVGQNF- 159
            |:.|:.|...|||:||:..|:||||...|..|||||:.:.|....|: |.|||:||:.:||:.|
Worm    73 IRPPSGLNALCDYNVFRDDIQPMWEVPENSNGGRWLIVIDKGKTPEMVDAIWLEILMALVGEQFG 137

  Fly   160 EYSDEICGAVINIRNKSNKISVWTANGSNEMAILEIG--QKLKILLHLQSHS------LQYQLHS 216
            :..:.|||.|.|:|.|.:||||||.:.:::...:.||  .|.|::...:.||      ::|:.|.
Worm   138 KDMESICGLVCNVRGKGSKISVWTKDCNDDETNMRIGVVLKEKLMAASKDHSKPLFDVIRYEDHE 202

  Fly   217 DAMSKFNSGVKSVYTL 232
            ....|.:|.||:..:|
Worm   203 SCQKKTSSVVKAKLSL 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF4E5	NP_648160.2	IF4E	59..212	CDD:279921	64/162 (40%)
ife-1	NP_001255196.1	IF4E	37..181	CDD:279921	61/143 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156168
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54586
OrthoDB	1	1.010	-	-		D1394271at2759
OrthoFinder	1	1.000	-	-		FOG0000666
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11960
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X406
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.960