DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32369 and Bfar

DIOPT Version :9

Sequence 1:	NP_001246660.1	Gene:	CG32369 / 38873	FlyBaseID:	FBgn0052369	Length:	1066	Species:	Drosophila melanogaster
Sequence 2:	NP_001013143.1	Gene:	Bfar / 304709	RGDID:	1304791	Length:	450	Species:	Rattus norvegicus

Alignment Length:	333	Identity:	70/333 - (21%)
Similarity:	110/333 - (33%)	Gaps:	99/333 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 MDEAGDSPLDMHSPTRE--LRVPSPLQDLEDFDPLMCPLCSDILRCPVTTNCGHTFCRQC----- 206
            |:|...:.|.|.....:  :|...|...:.:|.   |..|.|.|..|.|.||||:|||.|
  Rat     1 MEEPQKNDLSMRGQEEDHPVRSSGPQISVSEFS---CHCCYDTLVNPTTLNCGHSFCRHCLALWW 62

  Fly   207 -CETITQCNICQVR---FPRIQASSPGPPVCALTTTTASGAGSSLFTAPSNHNANLSLISFPVGY 267
             ....|:|..|:.:   ||::             ......|...||.         ..|...|..
  Rat    63 MSSKKTECPECREKWEGFPKV-------------NILLRDAIEKLFP---------DAIKMRVED 105

  Fly   268 GVQLSSSVQRLAA--------PPMTVTTTTV--------ASTTATATTTMASTSAAAALGLSAY- 315
            ..|.:..||.|||        .|:..:|..|        .|...||.|       ..|:.|..|
  Rat   106 IQQNNDVVQSLAAFQKYGNDQNPLAPSTGRVNQQRGGGFFSGVLTALT-------GVAVILLVYH 163

  Fly   316 ----PSAHGGGIGSTAMKFMPDVLVRRLVEKW--------------WGPDLQAKKISEKASSCMH 362
                .|.||             :||.:.|:||              |....:.:.:||:.:..:.
  Rat   164 WRSRESEHG-------------LLVHKAVDKWTTEEVVLWLEQLGPWASLYRDRFLSERVNGRLL 215

  Fly   363 LNLLDDALKFCNASLEKSPANFKSLCLRAEVLLKLSHYQS-SLADIENALRTRCTSPKAHYLRAL 426
            |.|.::       ...::|...::...|..:|::|...:: .:...:|....:..:|........
  Rat   216 LTLTEE-------EFSRAPYTIENSSHRRVILMELERVRALGVKPPQNLWEYKAVNPGRSLFLLY 273

  Fly   427 ALSGLGRL 434
            ||....||
  Rat   274 ALKSSPRL 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32369	NP_001246660.1	RING	183..>206	CDD:302633	13/22 (59%)
		TPR_11	349..412	CDD:290150	9/63 (14%)
		TPR repeat	350..378	CDD:276809	4/27 (15%)
		TPR_11	383..449	CDD:290150	9/53 (17%)
		TPR repeat	383..413	CDD:276809	4/30 (13%)
		RING	687..729	CDD:238093
		LON	791..1005	CDD:271862
		LON_substr_bdg	802..1001	CDD:280370
Bfar	NP_001013143.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..24		5/22 (23%)
		RING-HC_BAR	32..77	CDD:319411	18/47 (38%)
		SAM_BAR	179..249	CDD:188912	12/76 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2802
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900