Protein Alignment CG32369 and LOC1270179

DIOPT Version :10

• Sequence 1: NP_729296.1
• Gene: CG32369 / 38873
• FlyBaseID: FBgn0052369
• Length: 1066
• Species: Drosophila melanogaster
• Sequence 2: XP_308856.4
• Gene: LOC1270179 / 1270179
• VectorBaseID: AGAMI1_010800
• Length: 1009
• Species: Anopheles gambiae
• Alignment Length: 968
• Identity: 375/968 - (38%)
• Similarity: 503/968 - (51%)
• Gaps: 243/968 - (25%)

  Fly   179 DPLMCPLCSDILRCPVTTNCGHTFCRQCCETITQCNICQVRFPRIQASSPGPPVCALTTTTASGA 243
            |.|.||:|..:||.|||..||||||||||....:|.:|..|||.: |.:|          .||.:
Mosquito   147 DGLCCPICEGVLRYPVTATCGHTFCRQCCFGHGRCTVCGQRFPSV-AGAP----------AASSS 200

  Fly   244 GSSLFTAPSNHNANLSLISFPVGYGVQLSSSVQRLAAPPMTVTTTTVASTTATATTTMASTSA-- 306
            ...:||                             :.|..:|::.:.:|::::||.|..|..|
Mosquito   201 APVVFT-----------------------------STPSASVSSASGSSSSSSATVTSGSFRALP 236

  Fly   307 AAALGLSAYPSAHGGGIGSTAMKFMPDVLVRRLVEKWWGPDLQAKKISEKASSCMHLNLLDDALK 371
            |...|....|:|..|        |..|:|:|||||:||.|:|:|..:.|:|...:..|.||:||:
Mosquito   237 APEEGSELAPAASVG--------FELDILIRRLVERWWAPELKAADLHEEAQRHLEDNSLDEALR 293

  Fly   372 FCNASLEKSPANFKSLCLRAEVLLKLSHYQSSLADIENALRTRCTSPKAHYLRALALSGLGRLEE 436
            .||.|||..|.:.|.|.||:|||.:|.||||:|||.::||:...||.||||.||.:||.||:.||
Mosquito   294 CCNQSLEHVPNSAKGLQLRSEVLHRLHHYQSALADADSALKCLPTSHKAHYCRAKSLSALGKYEE 358

  Fly   437 ALYNGFLAICLDKKTNLSNSEIFQHDLAKILQRLL---AHMPKNRTSLSSATVP----------- 487
            |:....|:|.||:::....|.| :.:|.:.||:||   |.:..:|.:|:....|
Mosquito   359 AIIARCLSIFLDRQSQAVPSGI-KSELMQDLQQLLFEPASVAGSRGALTDYHSPSEPDDPLGLML 422

  Fly   488 ---------VFQQQHR--NFATSRAPYPLLWEQVRRRRKQQHHHHHHHHHHHVHLDDVEDEFGHY 541
                     ..:::||  ..||.|          |:.:||         ...:...|.:::...|
Mosquito   423 DHSYDLIAGCRKRRHRCDPLATQR----------RKSKKQ---------FLTLRQGDFDEDHSDY 468

  Fly   542 NNYIMAGDDMEEEVEVEVEGGEPGSLHLDGDFLFPSALDFMDHHRHQRHVFEQKQFDLQP----- 601
                 .|||                 :|..:.||    |:||      ..|.::.. |.|
Mosquito   469 -----GGDD-----------------YLSSELLF----DYMD------DPFSEESL-LGPVPTRN 500

  Fly   602 -RRHANRKHCKRKWSVAMESMGGKDLEEEDVDRAHAAGESQ-------------------RCSRL 646
             |:|  |.|.:|:.......:...||..|...|.|...::|                   :.|..
Mosquito   501 QRQH--RSHHRRRRKSGSALLLQSDLRLEQHLRDHQYHQAQYQAPHLVEPKQEQCDSIIPQASAR 563

  Fly   647 FAGVLDRTQQELQRLKKLDKSAPSLAVSSVAGQLIDASDFDCVVCSRTLWKPVVTPCGHTYCLVC 711
            ...:|:|...|||..:.||.:...|||:.   .||:.||||||:|.||||:|||||||||||.||
Mosquito   564 LKSLLERLDGELQSARWLDTTPVRLAVNP---SLIEPSDFDCVLCCRTLWRPVVTPCGHTYCWVC 625

  Fly   712 LDRCMDYNSPCPLCMSPLVEFNVNASASTSASQHPNPNQNQIHLHPGSSSPVP------------ 764
            |||||||:|.|||||:||||                  |.:.|| |||::..|
Mosquito   626 LDRCMDYSSSCPLCMAPLVE------------------QFRNHL-PGSAATPPEAAAAGPASPST 671

  Fly   765 --FALAKRPVTKFLEAAMKRFIPDHYEARFRQEIDQEPSVPVFICTAAFPAVPCPLFVCEPRYRL 827
              .:||||.:|:|::.||:||||:.||.|.:||.|:||:|||||||.|||:|||||||.|.||||
Mosquito   672 NLISLAKRKMTRFVDLAMQRFIPEAYERRQQQEQDREPTVPVFICTTAFPSVPCPLFVYEQRYRL 736

  Fly   828 MVRRAVESGDKTFGIVQP-NGGKSRYYDVGTILDIRDCVQLGDGCSILSTIGCKRFKILARNEKD 891
            |||||:|||::.|||..| ..|:.||.:.||:||||||||||||||||||:|.:||::|.|:|:|
Mosquito   737 MVRRAIESGERRFGIALPAQNGRQRYVEYGTMLDIRDCVQLGDGCSILSTVGGRRFRVLTRHERD 801

  Fly   892 GYETAKVEYICDEPI------ADEQVKILAGMQGVVLAKASEWFESLSTEQKHEILQSFGQMPPL 950
            ||:||.||:..||.|      |||:::::..:...||.||.||.:||....:.||.:|||:||.|
Mosquito   802 GYDTAHVEFFEDEKIHGGSTEADERLQLVRDLHEKVLLKAIEWHQSLPESIRCEIFKSFGKMPDL 866

  Fly   951 EPNWELISDGPAWAWWIIALLPLSQQLKVDILATTSLEKRLRAIDKTLD---------------- 999
            |.|||.::|||||||||||:|||:.:||||||:||||:||||||||||:
Mosquito   867 EENWEDVTDGPAWAWWIIAILPLNDKLKVDILSTTSLKKRLRAIDKTLNLESAQQKRQRSVCVMA 931

  Fly  1000 -----WLHDLSHPQQ------------------PAHHPMNHHQQAPQSP----QQAHH 1030
                 ....||..||                  ..|||  ||....||.    |..||
Mosquito   932 GASSACCEGLSSTQQCQAIDCCLRERTTSSVHNHHHHP--HHDSDRQSDSTQHQHLHH 987

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32369	NP_729296.1	RING_Ubox	179..222	CDD:473075	24/42 (57%)
		TPR repeat	350..378	CDD:276809	11/27 (41%)
		TPR	357..>438	CDD:440225	43/80 (54%)
		Spy	363..>517	CDD:443119	65/178 (37%)
		TPR repeat	383..413	CDD:276809	17/29 (59%)
		RING-HC_LONFs_rpt2	685..729	CDD:438177	36/43 (84%)
		LON/PUA	811..999	CDD:442054	121/194 (62%)
LOC1270179	XP_308856.4	None