DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32369 and LOC102557137

DIOPT Version :9

Sequence 1:	NP_001246660.1	Gene:	CG32369 / 38873	FlyBaseID:	FBgn0052369	Length:	1066	Species:	Drosophila melanogaster
Sequence 2:	XP_038956438.1	Gene:	LOC102557137 / 102557137	RGDID:	7505527	Length:	351	Species:	Rattus norvegicus

Alignment Length:	413	Identity:	76/413 - (18%)
Similarity:	134/413 - (32%)	Gaps:	127/413 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   664 LDKSAPSLAVSSVAGQLIDASDFDCVVCSRTLWKPVVTPCGHTYCLVCLDRCM-DYNSPCPLCMS 727
            |.|:.|           :...|..|::|...|.:|:..||.||.|..|....: ..|..||.|.|
  Rat     3 LSKAKP-----------LSLEDCQCLLCMEFLIEPITMPCNHTMCKSCFKALLRKTNLFCPFCRS 56

  Fly   728 PLVEF-----NVNASASTS-----ASQHP------NPNQNQIHLHPGSSSPV-----PFAL---- 767
            .:..:     :||:..:..     .:|:|      .|.:.:..|.....||:     |..|
  Rat    57 WISSWARYHTHVNSLINKELWERIQTQYPEECRRRTPGEERSSLVFSDHSPIRVLSNPGELRKEY 121

  Fly   768 --------AKRPVTK---------FLEAAMKRFIPDH---YEARFRQEIDQEPSVPVFICTAAFP 812
                    |:|..||         :::..:.:.:.:.   .|.|..:|.:|.........:.:.|
  Rat   122 EEQLIKMEAERQATKERQNRATEEYIKQLLAKELEEEKMWAEKRRLEEREQREEEEAKKSSTSDP 186

  Fly   813 AVPCPLFVCEPRYRLMVRRAVESGDKTFGIVQPNGGKSRYYDVGTILDIRDCVQLGDGCSILSTI 877
                   |..||.:...|:..:...| |...||....:..|:  |:.|.:            .|.
  Rat   187 -------VTSPRKKKSKRKHCDDVPK-FSPHQPQLESALLYE--TVQDSK------------KTS 229

  Fly   878 GCKRFKILARNEKDGYETAKVEYICDEPIADEQVKILAGMQGVVLAKASEWFESLSTEQKHEILQ 942
            |.|             :.||.|               ..|....|:...|..:..::..::|:..
  Rat   230 GRK-------------QEAKTE---------------ENMSAATLSTGPENPQQGTSNSRYEVFS 266

  Fly   943 SF----GQMPPLEPNWELISDGPAWAWWIIALLPLSQQLKVDILATTS-----LEKRLRAIDKTL 998
            ::    |......|.....:        |...:| |:.:|.:....||     :.|.....:.|:
  Rat   267 NYDAKVGSSEDEAPKASCSN--------IDCYVP-SKNIKPEANIHTSAQRETMSKTEETGNSTI 322

  Fly   999 DWLHDLSHPQQPAHHPMNHHQQA 1021
            :....:|||......|  |:|:|
  Rat   323 EAKEKMSHPSSGITRP--HYQKA 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32369	NP_001246660.1	RING	183..>206	CDD:302633
		TPR_11	349..412	CDD:290150
		TPR repeat	350..378	CDD:276809
		TPR_11	383..449	CDD:290150
		TPR repeat	383..413	CDD:276809
		RING	687..729	CDD:238093	15/42 (36%)
		LON	791..1005	CDD:271862	35/222 (16%)
		LON_substr_bdg	802..1001	CDD:280370	32/207 (15%)
LOC102557137	XP_038956438.1	RING_Ubox	16..55	CDD:418438	13/38 (34%)
		RING-HC finger (C3HC4-type)	16..54	CDD:319361	13/37 (35%)
		UDM1_RNF168	111..>160	CDD:409018	6/48 (13%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D458276at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010