Protein Alignment CG32369 and lonrf3

DIOPT Version :10

• Sequence 1: NP_729296.1
• Gene: CG32369 / 38873
• FlyBaseID: FBgn0052369
• Length: 1066
• Species: Drosophila melanogaster
• Sequence 2: XP_002934588.3
• Gene: lonrf3 / 100486178
• XenbaseID: XB-GENE-985290
• Length: 738
• Species: Xenopus tropicalis
• Alignment Length: 916
• Identity: 223/916 - (24%)
• Similarity: 352/916 - (38%)
• Gaps: 273/916 - (29%)

  Fly   112 SPRISERLDMMPWSRYHHQGKQNQAEQGEFLRGVGESMDEAGDSPLDMHSPTRELRVPSPLQDLE 176
            |.|:.:..|:...:..|   |:..||..|.|           .|.|..|..|:| .:|.|.|.:.
 Frog    58 SGRLQDACDLFQRAAMH---KKVCAEDLEAL-----------VSCLADHIRTKE-GLPPPDQRVA 107

  Fly   177 DFDPLMCPLCSDILRCPVTTNCGHTFCRQCCE----TITQCNICQVRFPRIQASSPGPPVCALTT 237
            ....|.|..|......|||..||||||::|.|    :.::|.:|:|
 Frog   108 KSAVLTCRQCQGFFFEPVTLLCGHTFCKKCLECQGGSKSECKVCRV------------------- 153

  Fly   238 TTASGAGSSLFTAPSNHNANLSLISFPVGYGVQLSSSVQRLAAPPMTVTTTTVASTTATATTTMA 302
                                                                             
 Frog   154 ----------------------------------------------------------------- 153

  Fly   303 STSAAAALGLSAYPSAHGGGIGSTAMKFMPDVLVRRLVEKWWGPDLQAKKISEKASSCMHLNLLD 367
                                  ||...|..:||:..::.||:...::|.::.::.::.......:
 Frog   154 ----------------------STEHPFRVNVLLSNILSKWFPSQVKAVRLRQEGNALYKDCKWE 196

  Fly   368 DALKFCNASLEKSPANFKSLCLRAEVLLKLSHYQSSLADIENALRTRCTSPKAHYLRALALSGLG 432
            :||...|.::..:|.:......||.:...|..|..:|.|.|...:.:....|.|..:|.:|..||
 Frog   197 EALARYNEAISIAPQDHLLYSNRAMIHFSLKSYGCALQDAETTCKLQPYWLKGHLRKAQSLVNLG 261

  Fly   433 RLEEALYNGFLAICLDKKT------------NLSNSEIFQHDLAKILQRLLAHMPKNRTSLSSAT 485
            |.|::|......:.|:.:.            ||.:.:..|.||.:|||.:...:......|:|.:
 Frog   262 RSEDSLKEFLFCLALETENRTAKCEAQKLLLNLLSLQNNQGDLPEILQTMSHPLRLKGNVLNSLS 326

  Fly   486 VPVFQQQHRNFATSRAPYPLLWEQVRRRRKQQHHHHHHHHHHHVHLDDVEDEFGHYNNYIMAGDD 550
            .|......:..           :.|....|:           .|.:.|..|..|:.:.::: ...
 Frog   327 TPTPSSNMQRL-----------KMVNMDIKK-----------GVTISDDTDPKGNSSMWLL-HQT 368

  Fly   551 MEEEVE----VEVEGGEPGSLHLDGDFLFPSALDFMDHHRHQRHVFEQKQFDLQPRRHANRKHCK 611
            .|.|:.    .:....||.:       |.|||.:.:                       .||.|.
 Frog   369 RESELSCSEMTKAFTPEPAA-------LVPSACNTL-----------------------KRKACS 403

  Fly   612 RKWSVAMESMGGKDLEEEDVDRAHAAGESQRCSRLFAGVLDRTQQELQRLKKLDKSAPSLAVSSV 676
            ::...:.|.:..|.|:.:      ||         ..|.|..           |.|:.|
 Frog   404 KETECSSEHIPCKALKRD------AA---------VTGTLGN-----------DHSSAS------ 436

  Fly   677 AGQLIDASDFDCVVCSRTLWKPVVTPCGHTYCLVCLDRCMDYNSPCPLCMSPLVEFNVNASASTS 741
               .:|.||.||.:|.|.|::||.|||||||||.||:||:|:|..||||...|.|:
 Frog   437 ---CVDLSDLDCSLCMRLLYEPVTTPCGHTYCLKCLERCLDHNPKCPLCKEDLCEY--------- 489

  Fly   742 ASQHPNPNQNQIHLHPGSSSPVPFALAKRPV--TKFLEAAMKRFIPDHYEAR---FRQEIDQ--- 798
                                     ||.|..  |:.:|..:..:.||..:.|   :.:||.:
 Frog   490 -------------------------LAIRTFCKTELMEDLIASYFPDELKDRKTVYEEEIAELSN 529

  Fly   799 -EPSVPVFICTAAFPAVPCPLFVCEPRYRLMVRRAVESGDKTFGIVQPNGGKSRYYDVGTILDIR 862
             ..:||:|:||.|:|.|||||.:.||.||||:||.:|:|.|.||:...:..|. :.|.|.:|:||
 Frog   530 LNKNVPIFVCTMAYPTVPCPLHIFEPCYRLMIRRCMETGTKQFGMCIGDSVKG-FADYGCMLEIR 593

  Fly   863 DCVQLGDGCSILSTIGCKRFKILARNEKDGYETAKVEYICDEPIADEQVKILAGMQGVVLAKASE 927
            :.....||.|::.:||.:|||::..:::|||.||.:|||.|.....::...|..:...|..:|..
 Frog   594 NVEFFADGRSVVDSIGKRRFKVIRHSQRDGYNTADIEYIEDHKAQGQEYDDLLTLHNAVYDQAFN 658

  Fly   928 WFESLSTEQKHEILQSFGQMPPLEPNWELISDGPAWAWWIIALLPLSQQLKVDILATTSLEKRLR 992
            ||.:|....|..||..||.||..:.:.:...:||||.|||:|:|||..:.::..||.|||:.||.
 Frog   659 WFSTLKPALKSRILSHFGPMPANDCDIQANPNGPAWCWWILAVLPLESRAQLPFLAMTSLKDRLT 723

  Fly   993 AIDKTL 998
            .|.:.|
 Frog   724 GIRRVL 729

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32369	NP_729296.1	RING_Ubox	179..222	CDD:473075	17/46 (37%)
		TPR repeat	350..378	CDD:276809	4/27 (15%)
		TPR	357..>438	CDD:440225	19/80 (24%)
		Spy	363..>517	CDD:443119	34/165 (21%)
		TPR repeat	383..413	CDD:276809	7/29 (24%)
		RING-HC_LONFs_rpt2	685..729	CDD:438177	27/43 (63%)
		LON/PUA	811..999	CDD:442054	75/188 (40%)
lonrf3	XP_002934588.3	RING-HC_LONFs_rpt1	111..155	CDD:438176	17/149 (11%)
		TPR repeat	179..207	CDD:276809	4/27 (15%)
		TPR	186..>283	CDD:440225	21/96 (22%)
		TPR repeat	212..242	CDD:276809	7/29 (24%)
		TPR repeat	247..270	CDD:276809	9/22 (41%)
		RING-HC_LONFs_rpt2	442..486	CDD:438177	27/43 (63%)
		LON/PUA	543..729	CDD:442054	74/186 (40%)