Protein Alignment Clk and arnt2

DIOPT Version :10

• Sequence 1: NP_001014576.1
• Gene: Clk / 38872
• FlyBaseID: FBgn0023076
• Length: 1027
• Species: Drosophila melanogaster
• Sequence 2: XP_009301213.1
• Gene: arnt2 / 64277
• ZFINID: ZDB-GENE-001207-3
• Length: 738
• Species: Danio rerio
• Alignment Length: 689
• Identity: 147/689 - (21%)
• Similarity: 260/689 - (37%)
• Gaps: 189/689 - (27%)

  Fly     2 DDESDDKDDTKSFLCRKSRNLSEKKRRDQFNSLVNDLSALISTSS---RKMDKSTVLKSTIAFLK 63
            ||:....|  |....|::.:..|::||::....:.:||.::.|.|   ||.||.|:|:..::.:|
Zfish    67 DDDQIPGD--KERYARENHSEIERRRRNKMTQYITELSDMVPTCSALARKPDKLTILRMAVSHMK 129

  Fly    64 N----HNEATDRSKVFEIQQDWKPAFLSNDEYTHLMLESLDGFMMVFSS-MGSIFYASESITSQL 123
            :    .|.:||.:        :||:||:..|..||:||:.|||:.|.:: .|.:.|.|:|:|..|
Zfish   130 SMRGTGNTSTDGA--------YKPSFLTEQELKHLILEAADGFLFVVAAETGRVIYVSDSVTPVL 186

  Fly   124 GYLPQDLYNMTIYDLAYEMDHEALLNIFMNPTPVIEPRQTDISS----------------SNQIT 172
            .:...:.:..|:::..:..|.:.|..........:..|..|:.:                .::.:
Zfish   187 NHPQSEWFGSTLFEQVHPDDVDKLREQLSTSENSMTGRILDLKTGTVKKEGQQSSMRMCMGSRRS 251

  Fly   173 FYTHLRRG-----------------------GMEKVDANAYELVKFVGYFR---------NDTNT 205
            |...:|.|                       |..|.....|.:|...||.:         .|.:|
Zfish   252 FICRMRCGSAPLDHISLNRLSSMRKRYRNGLGPSKEGEAQYSVVHCTGYIKAWPPAGMTIPDEDT 316

  Fly   206 STGSSSEVSNGSNGQPAVLPRIFQQNPNAEVDKKLVFVGTGRVQ---NPQLIREMSIIDPTSNEF 267
            ..|.:|                           |...|..||:|   :|..:....:..||  ||
Zfish   317 EAGQTS---------------------------KYCLVAIGRLQVTSSPVSMDMNGLSVPT--EF 352

  Fly   268 TSKHSMEWKFLFLDHRAPPIIGYMPFEVLGTSGYDYYHFDDLDSIVACHEELRQT----GEGKSC 328
            .|:|:.:....|:|.|...:|||.|.::||....::.|.:|...:   .|..:|.    |:..|.
Zfish   353 LSRHNSDGIITFVDPRCINVIGYQPQDLLGKDILEFCHPEDQSHL---RESFQQVVKLKGQVLSV 414

  Fly   329 YYRFLTKGQQWIWLQTDYYVSYHQFNSKPDYVVCTHKVVSYAE-----VLKDSRKEGQKSGNSNS 388
            .|||..|.::|:.::|..:...:.::.:.:|::||:..|...:     .|:..:::|..:.:.:.
Zfish   415 MYRFRMKNREWMLIRTSSFTFQNPYSDEIEYIICTNTNVKQLQQQQQAELEVHQRDGLTAYDLSQ 479

  Fly   389 ITNNGSSKVIASTGTS-SKSASATTTLRD---------FELSSQNL---DSTLLGNSLASLGT-- 438
            :..:|.|..:..:|.| .|:.|..:..||         ...|.:.:   .||..|..|.|.|:
Zfish   480 VPVSGVSAGVHESGKSIDKTESLFSQERDPRFSDIYTGISTSEKKMMVPSSTSGGQQLYSQGSPF 544

  Fly   439 ----------------------ETAATSPAVDSSPM----------WSASAVQPSGSCQINPLKT 471
                                  ::.|.|...:.|.:          ||.:....||..|| |.::
Zfish   545 QPGHSGKSFSSSVIHVPGVNDIQSTAGSAGQNLSQISRQINTGQVSWSGNRPPFSGQQQI-PAQS 608

  Fly   472 SR----------------PASSYGNISSTGISPKAKRKCYFYNNRGNDSDSTSMSTDSVTSRQSM 520
            ::                ..|||..:||...|..:........||....|.:..|:.|....|..
Zfish   609 NKAQSSPFGIGSSHSYQADPSSYSPLSSPATSSPSGNAYSNLANRNTAFDVSGESSQSGGQFQGR 673

  Fly   521 MTHVSSQSQRQRSHHREHHRENHHNQS----HHHMQQQQ 555
            .:.|.||.|.|           ||:|.    |.|.|..|
Zfish   674 PSEVWSQWQSQ-----------HHSQQAGDPHPHTQASQ 701

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Clk	NP_001014576.1	bHLH-PAS_dCLOCK	11..86	CDD:381578	21/81 (26%)
		PAS	93..153	CDD:214512	17/60 (28%)
		PAS_11	265..368	CDD:464214	28/106 (26%)
arnt2	XP_009301213.1	bHLH-PAS_ARNT	75..139	CDD:381517	17/63 (27%)
		PAS	152..258	CDD:395786	21/105 (20%)
		PAS_11	351..451	CDD:464214	28/102 (27%)