Protein Alignment Clk and aha-1

DIOPT Version :9

• Sequence 1: NP_001014576.1
• Gene: Clk / 38872
• FlyBaseID: FBgn0023076
• Length: 1027
• Species: Drosophila melanogaster
• Sequence 2: NP_001251327.1
• Gene: aha-1 / 172889
• WormBaseID: WBGene00000095
• Length: 453
• Species: Caenorhabditis elegans
• Alignment Length: 463
• Identity: 99/463 - (21%)
• Similarity: 181/463 - (39%)
• Gaps: 122/463 - (26%)

  Fly     1 MDDE------------SDDKDDTKSFLCRKSRNLSEKKRRDQFNSLVNDLSALI---STSSRKMD 50
            |:||            .|:..:.|....|::.:..|::||::....:|:|:.::   ::..||.|
 Worm    18 MEDEDMGMPSGKYARMEDEMGENKERFARENHSEIERRRRNKMTHYINELAEMVPQCASLGRKPD 82

  Fly    51 KSTVLKSTIAFLKNHNEATDRSKVFEIQQDWKPAFLSNDEYTHLMLESLDGFM-MVFSSMGSIFY 114
            |.|:|:..::.:|.     .|....:.:..:||:||::.|..||:||:.:||: :|....|.:.|
 Worm    83 KLTILRMAVSHMKG-----IRGHTAQDETSYKPSFLTDQELKHLILEAANGFLFVVCCQTGKVLY 142

  Fly   115 ASESITSQLGYLPQDLYNMTIYDLAYEMDHEALLN------IFMNPTPVI-------EPRQTDIS 166
            .::|||..|....:|.....:.:|.:..|.:.:.:      :.:|....:       |...|.:.
 Worm   143 VADSITPVLNLKQEDWLQRNLNELIHPDDQDKIRDQLCGSEVSVNKVLDLKSGSVKREGASTRVH 207

  Fly   167 SSNQITFYTHLRRGGMEKVD------------ANAYELVKFVGYFRNDTNTSTGSSSEVSNGSNG 219
            .|.:..|...:|.|.:|.:.            ...|.::...||.:                 |.
 Worm   208 MSCRRGFICRMRVGALEPLHRLRNRRPLFQHAGQNYVVMHCTGYIK-----------------NA 255

  Fly   220 QPAVLPRIFQQNPNAEVDKKLVFVGTGRVQNPQLIREMSI-IDPTS-NEFTSKHSMEWKFLFLDH 282
            .|        |..||.....||.:  .|:|    :..|.: .|||| |:|:.:.|.:.|..|:|.
 Worm   256 PP--------QGINAPASSCLVAI--ARLQ----VASMPVCADPTSTNQFSVRVSEDGKMTFIDA 306

  Fly   283 RAPPIIGYMPFEVLGTSGYDYYHFDD----LDSIVACHEELRQTGEGKSCYYRFLTKGQQW---- 339
            |...:||....:::|...::..|..|    .||.||                  |...|..
 Worm   307 RVSDLIGLSSDQLIGRYWWNLAHPADEKTLQDSFVA------------------LLSDQPMRINI 353

  Fly   340 -IWLQTDY-------YVSYHQFNSKPDYVVCTHKV---------VSYAEVLKDSRKEGQKSGNSN 387
             :...|||       |...:.::.:.:|||.||::         |:...|.:....|..:.|.:.
 Worm   354 RVRTSTDYIPCTVSAYKFMNPYSEQFEYVVATHQIAPQEDINNWVTAPTVPQPQASEFGELGGAP 418

  Fly   388 SITNNGSS 395
            |..:.|.|
 Worm   419 SAVDYGQS 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Clk	NP_001014576.1	HLH	16..68	CDD:238036	13/54 (24%)
		PAS	93..153	CDD:214512	16/66 (24%)
		PAS	264..366	CDD:238075	28/118 (24%)
		PAS_11	265..368	CDD:291273	27/127 (21%)
aha-1	NP_001251327.1	HLH	46..98	CDD:278439	13/56 (23%)
		PAS	117..219	CDD:279347	22/101 (22%)
		PAS	120..179	CDD:214512	16/58 (28%)
		PAS	288..388	CDD:238075	27/117 (23%)
		PAS_11	289..393	CDD:291273	27/121 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910