Protein Alignment Clk and LOC1279488

DIOPT Version :10

• Sequence 1: NP_001014576.1
• Gene: Clk / 38872
• FlyBaseID: FBgn0023076
• Length: 1027
• Species: Drosophila melanogaster
• Sequence 2: XP_061513965.1
• Gene: LOC1279488 / 1279488
• VectorBaseID: AGAMI1_006591
• Length: 647
• Species: Anopheles gambiae
• Alignment Length: 629
• Identity: 131/629 - (20%)
• Similarity: 237/629 - (37%)
• Gaps: 169/629 - (26%)

  Fly    18 KSRNLSEKKRRDQFNSLVNDLSALI---STSSRKMDKSTVLKSTIAFLKNHN---------EATD 70
            ||:| :.:.||::.|....:|:.|:   |..:.::||:::::.|.::||...         ..||
Mosquito    27 KSKN-AARSRREKENVEFLELAKLLPLPSAITSQLDKASIIRLTTSYLKMRQIFPEGLGTAWGTD 90

  Fly    71 RSKVFEIQQDWKPAFLSNDEYTHLMLESLDGFMMVFSSMGSIFYASESITSQLGYLPQDLYNMTI 135
            |:.    |.:.:.|.:.  |....:|::||||:.|.:..|.|.|.||:.:..||....:|...:|
Mosquito    91 RNH----QPNGRAANIK--ELGSHLLQTLDGFIFVVAPDGKITYISETASVHLGLSQVELTGNSI 149

  Fly   136 YDLAYEMDHEALLNIFM-----NPTPVIEPR-----QTDISSSNQI------TF----------- 173
            |:..:..|.|.:.:|..     :|.....|.     .|.::|.|.:      ||
Mosquito   150 YEYIHAYDQEEMASILALQQPHHPLACSAPHNLPTSSTSLNSPNSLGTPWTGTFQVGSSATDSGY 214

  Fly   174 --------------------------------------------------------------YTH 176
                                                                          |:.
Mosquito   215 NEASSEAPVTLASCQQQQHQQQQQQQQQNHQYYVPSIPQAVKCESTQIHCQQNHHQPNHRHSYSQ 279

  Fly   177 LRRGGMEKVDANAYELVKFVGYFRNDTNTSTGSSSEVSNGSNGQPA-VLPRIFQQNPNAEVDKKL 240
            .:|..:..::.|.:..::.|...||...||:|  .:|.:.|....| |.|......|.....:.|
Mosquito   280 HQRSYVVDMERNFFLRMRCVLAKRNAGLTSSG--YKVIHCSGYLKARVFPHESLNTPGYCCVQNL 342

  Fly   241 VFVGTGRVQNPQLIREMSIIDPTSNEFTSKHSMEWKFLFLDHRAPPIIGYMPFEVLGTSGYDYYH 305
            .....|...:|....|:.:   ..|.|..:.|::.|.::||.:...:.||.|.:::..:.|.|.|
Mosquito   343 GLEAVGHSLSPSAATEVKL---QQNMFMFRASLDMKLIYLDAKVSQLTGYEPQDLIENTLYQYIH 404

  Fly   306 FDDLDSIVACHEELRQTGEGKSCYYRFLTKGQQWIWLQTDYYVSYHQFNSKPDYVVCTHKVVS-- 368
            ..|:..:...|:.|.|.|:..:.|||||||...|.|:|:...:.::..:|:|..:|..:.|:|
Mosquito   405 ASDVVQVRQTHQTLLQKGQATTMYYRFLTKAGGWRWVQSHATIVHNTRSSRPHCIVSVNYVLSDF 469

  Fly   369 YAEVLKDSRKEGQKSGNSNSITNNGSSKVIASTGTSSKSASATTTLRDFELSSQNLDSTLLGNSL 433
            .|:.|:.:..:|.||                |..:|.:..:.|.|......:|:...|....|..
Mosquito   470 EAQNLQLNESQGAKS----------------SLRSSFEMFNFTPTTHHHSAASEECMSAKAFNGN 518

  Fly   434 ASLGTETAATSPAVDSSPMWSASAVQPSGSCQ-----IN---PLKTSRPASSYGNISSTGISPKA 490
            ..|.|...:.:..:...|:  |.:::|   |:     :|   .||::         .||.|:.
Mosquito   519 QQLSTHEESLAFNLPPEPL--APSIEP---CKEIDNFLNFHHTLKSN---------ESTSIAE-- 567

  Fly   491 KRKCYFYNNRGNDSDSTSMSTDSVTSRQSMMTHVSSQSQRQRSH 534
                  .|..||  |.:.:..|....:.|..|     :|.|.|:
Mosquito   568 ------LNGSGN--DDSFLPNDLCYDQSSQFT-----TQTQLSY 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Clk	NP_001014576.1	bHLH-PAS_dCLOCK	11..86	CDD:381578	19/79 (24%)
		PAS	93..153	CDD:214512	19/64 (30%)
		PAS_11	265..368	CDD:464214	31/102 (30%)
LOC1279488	XP_061513965.1	None