Protein Alignment Clk and LOC1276689

DIOPT Version :10

• Sequence 1: NP_001014576.1
• Gene: Clk / 38872
• FlyBaseID: FBgn0023076
• Length: 1027
• Species: Drosophila melanogaster
• Sequence 2: XP_061505132.1
• Gene: LOC1276689 / 1276689
• VectorBaseID: AGAMI1_000822
• Length: 1118
• Species: Anopheles gambiae
• Alignment Length: 1071
• Identity: 211/1071 - (19%)
• Similarity: 363/1071 - (33%)
• Gaps: 321/1071 - (29%)

  Fly    17 RKSRNLSEKKRRDQFNSLVNDLSAL---ISTSSRKMDKSTVLKSTIAFLKNHNEATDRSKVFEIQ 78
            |::||.:||.|||:.|..:.:|||:   ::.|.|::||:.||               |.....::
Mosquito   225 REARNRAEKNRRDKLNGSIQELSAMVPHVAESPRRVDKTAVL---------------RFSAHGLR 274

  Fly    79 QDW-----KPAFLSNDEYTHLMLESLDGFMMVFSSMGSIFYASESITSQLGYLPQDLYNMTIYDL 138
            .|:     ||......|....:...|:||::..:..|.|...|.|:...||:...|||...:::|
Mosquito   275 VDYVFGKSKPEETVKPEAQDSLFRMLNGFLLTVTCRGQIVLVSPSVEQFLGHCQTDLYGQNLFNL 339

  Fly   139 AYEMDH---------EALLNIFMNPTPVIE----PRQTDISSSNQITFYTHLRRGGME------- 183
            .:..||         ..|:|:|.|..|...    |.   :..|.:....||...||.|
Mosquito   340 THPDDHALLKQQLIPSNLVNMFDNGGPSTSCGAPPA---LLGSGEGGSGTHGTDGGGEFQRSYDD 401

  Fly   184 ------------------------KVDANAYELVKFVGYFRNDTNTSTGSSSEVS---------N 215
                                    :.:|..||||...|.||...:...||||..|         .
Mosquito   402 EEEIDRKLRQDHRRFTIRMARAGPRSEATTYELVTIDGCFRRADSAPRGSSSSSSATKAGAAGAG 466

  Fly   216 GSNGQPAVLPRIFQQN---PNAEVD-KKLVFVGTGRVQNPQLIREMSIIDPTSNEFTSKHSMEWK 276
            |:.|...::.|:..::   |...:: ..:|.:...||.....|.: .:|:....|:.::|.::.:
Mosquito   467 GTAGSMQMIRRVRGRDDAIPLHSINGNDIVLIALARVMKVPSICD-RLIEACKYEYKTRHLIDGR 530

  Fly   277 FLFLDHRAPPIIGYMPFEVLGTSGYDYYHFDDLD-SIVACHEELRQTGEGKSCYYRFLTKGQQWI 340
            .:..|.|...:.||:..||.|.|.:.:.|.||:. .|||..:.......|:|| ||.:::...:|
Mosquito   531 IVQCDQRISIVAGYLTDEVSGLSPFTFMHRDDVRWVIVALRQMYDYNQNGESC-YRLMSRTGDFI 594

  Fly   341 WLQTDYYVSYHQFNSKPDYVVCTHKVVSYAE---VLKDSRKEGQKSGNSNSITNNGSSKVIASTG 402
            :|:|..|:............||.:.:||..|   ::::.:::.....:...:.:.....|:.:.
Mosquito   595 YLKTRGYLEVDSDTKVVQSFVCINTLVSEEEGQRLVREMKRKFSVIVDKVELPDESGEPVVENP- 658

  Fly   403 TSSKSASATTTLRDFELSSQNLDSTLLGNSLASLGTETAATSPAVDSSPMWSASAVQPSGS--CQ 465
                        :..|.:..||.:.|..:|...|    ..|.||   ||..|..:....|:  ..
Mosquito   659 ------------KQIEEAVMNLITNLQPDSEDKL----LNTMPA---SPASSIKSGYGEGAPLAI 704

  Fly   466 INPLKTSRPASSYGNISSTGISPKAKRKCYFYNNRGND-----SDSTSMSTDSVTSRQSMMTHVS 525
            :.|.|.|..::...:|:...|:.|..|:....:..|.|     .|..:.:..|.|:..|:.|.:.
Mosquito   705 VAPEKNSVKSAIVKSINVVSIAAKTMREGRCSSVSGGDWSPLGGDQQNSNGSSGTASSSVSTGMP 769

  Fly   526 SQSQRQRSHHREHHRENHHNQSHHHMQQQQQHQNQQQQHQQHQQLQQQLQHTVGTPKMVPLLPIA 590
            |.|                                          :......:|:|...|..|
Mosquito   770 SPS------------------------------------------RSAFADGIGSPPPPPPAP-- 790

  Fly   591 STQIMAGNACQFPQPAYPLASPQLVAPTF---LEPPQYLTA----------IPMQP-----VIAP 637
                        |||:......|  .||.   |:||....|          :|..|     ...|
Mosquito   791 ------------PQPSLSPGGAQ--RPTVLQKLDPPLSEEAAAVGANVEQRVPPLPNSQHYFTQP 841

  Fly   638 FPVAPVLSPLPVQSQTDMLPDTVVMTPTQSQLQDQLQRK----------------H-----DELQ 681
            |..:...:|:||.          :::|..|....:..|.                |     ....
Mosquito   842 FSPSGGTTPVPVS----------LLSPASSHYSQRSARSPYGGCGSGIASPPAGIHGGGGGGSRT 896

  Fly   682 KLILQQQNELRIVSEQLLLSRYTYLQPMMSMGFAPGNMTAAAVGNLG------ASGQRGLNFTGS 740
            ..:|::......::....|..|             |:...|..|:.|      |.|...|....|
Mosquito   897 TTVLKRTYSNSSINSLNSLDNY-------------GDGGEAGTGDSGKRARMHALGNSDLANCFS 948

  Fly   741 NAVQPQFNQYGFALNSEQMLNQQDQQMMMQQQQNLHTQHQHNLQQQHQSHSQLQQHTQQQHQQQQ 805
            :.:.|..:......||.:.|:|  ..:.|:....:...........|:|.::|.:..
Mosquito   949 DLINPGSDLTSLLPNSFEALDQ--SLLTMETTTTIIRDRVSGYSSLHESQNRLDRIV-------- 1003

  Fly   806 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQLQLQQQNDILLREDIDDIDAFLNLSPLHSLGSQSTI 870
                       ::.|:|::..|..||:.|||:|.                      :..||.: |
Mosquito  1004 -----------EEHQEQREMLQSIQQEYQLQMQS----------------------NGTGSDA-I 1034

  Fly   871 NPFNSSSNNNNQSYNGGSNLNNGNQNNNNRSSNPPQNNNEDSLLSCMQMATESSPSINFHMGISD 935
            ...|.|..      .||.:..:|...|:       .:....::.|.|..||   |.:
Mosquito  1035 GAGNGSGG------GGGGDEPDGMLCNS-------LSQRVSTITSTMAAAT---PPL-------- 1075

  Fly   936 DGSETQSEDNKMMHTSGSNLVQQQQQQQQQQ 966
                       ||.:..::.|.||||||||:
Mosquito  1076 -----------MMPSVITSSVGQQQQQQQQR 1095

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Clk	NP_001014576.1	bHLH-PAS_dCLOCK	11..86	CDD:381578	22/76 (29%)
		PAS	93..153	CDD:214512	18/68 (26%)
		PAS_11	265..368	CDD:464214	27/103 (26%)
LOC1276689	XP_061505132.1	None