Protein Alignment Clk and Arntl

DIOPT Version :9

• Sequence 1: NP_001014576.1
• Gene: Clk / 38872
• FlyBaseID: FBgn0023076
• Length: 1027
• Species: Drosophila melanogaster
• Sequence 2: XP_006507308.1
• Gene: Arntl / 11865
• MGIID: 1096381
• Length: 638
• Species: Mus musculus
• Alignment Length: 611
• Identity: 154/611 - (25%)
• Similarity: 246/611 - (40%)
• Gaps: 167/611 - (27%)

  Fly     7 DKDDTKSFL-----------CRKSRNLSEKKRRDQFNSLVNDLSALIST---SSRKMDKSTVLKS 57
            ||||....|           .|::.:..||:|||:.||.:::|::|:.|   .|||:||.|||:.
Mouse    60 DKDDPHGRLEYAEHQGRIKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKLTVLRM 124

  Fly    58 TIAFLKNHNEATDRSKVFEIQQDWKPAFLSNDEYTHLMLESLDGFMMVFS-SMGSIFYASESITS 121
            .:..:|....||:.    ..:.::||.|||:||..||:|.:.|||:.|.. ..|.|.:.|||:..
Mouse   125 AVQHMKTLRGATNP----YTEANYKPTFLSDDELKHLILRAADGFLFVVGCDRGKILFVSESVFK 185

  Fly   122 QLGYLPQDLYNMTIYDLAYEMD---------------HEALLNIFMNPTPV---IEPRQTDISSS 168
            .|.|...||...:::|..:..|               .|.|::. ....||   |.|..:.:.|.
Mouse   186 ILNYSQNDLIGQSLFDYLHPKDIAKVKEQLSSSDTAPRERLIDA-KTGLPVKTDITPGPSRLCSG 249

  Fly   169 NQITFYTHLRRG---------------GMEKVDANAYELVKFVGYFRNDTNTSTGSSSEVSNGSN 218
            .:.:|:..::..               ..:|.|..::..:...||.::...|..|...:
Mouse   250 ARRSFFCRMKCNRPSVKVEDKDFASTCSKKKADRKSFCTIHSTGYLKSWPPTKMGLDED------ 308

  Fly   219 GQPAVLPRIFQQNPNAEVDKKLVFVGTGRVQN---PQLIR-EMSIIDPTSNEFTSKHSMEWKFLF 279
                       ..|:.|.......|..||:.:   ||... |:.:   .|.|:.|:|:::.||:|
Mouse   309 -----------NEPDNEGCNLSCLVAIGRLHSHMVPQPANGEIRV---KSMEYVSRHAIDGKFVF 359

  Fly   280 LDHRAPPIIGYMPFEVLGTSGYDYYHFDDLDSIVACHEELRQTGE--GKSCYYRFLTKGQQWIWL 342
            :|.||..|:.|:|.|:||||.|:|:|.||:..:..||.::.||.|  ..:| |:|..|...:|.|
Mouse   360 VDQRATAILAYLPQELLGTSCYEYFHQDDIGHLAECHRQVLQTREKITTNC-YKFKIKDGSFITL 423

  Fly   343 QTDYYVSYHQFNSKPDYVVCTHKVVSYAEVLKDSRKEGQKSGNSNSITNNGSSKVIASTGTSSKS 407
            ::.::...:.:..:.:|:|.|:.|| .|.||     ||
Mouse   424 RSRWFSFMNPWTKEVEYIVSTNTVV-LANVL-----EG--------------------------- 455

  Fly   408 ASATTTLRDFELSSQNLDSTL-LGNSLASLG--TETAATSPAVDSSPMWSASAV----------- 458
              ...|.........::||.| .|.....:|  ..|..|.|.:.......|..:
Mouse   456 --GDPTFPQLTAPPHSMDSMLPSGEDSFVVGGPKRTHPTVPGIPGGTRAGAGKIGRMIAEEIMEI 518

  Fly   459 ------QPSGSCQINPLK-TSRP---ASSYG----------NISSTGISPKAKRKC--YFYNNRG 501
                  .|| ||..:||. ||.|   |||.|          :|.|||:.|...::.  |.|::..
Mouse   519 HRIRGSSPS-SCGSSPLNITSTPPPDASSPGGKKILNGGTPDIPSTGLLPGQAQETPGYPYSDSS 582

  Fly   502 ---------------NDSDSTSMSTD 512
                           ||..|:|.|.|
Mouse   583 SILGENPHIGIDMIDNDQGSSSPSND 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Clk	NP_001014576.1	HLH	16..68	CDD:238036	20/54 (37%)
		PAS	93..153	CDD:214512	20/75 (27%)
		PAS	264..366	CDD:238075	37/103 (36%)
		PAS_11	265..368	CDD:291273	37/104 (36%)
Arntl	XP_006507308.1	bHLH-PAS_ARNTL_PASD3	74..137	CDD:381444	21/62 (34%)
		PAS	153..260	CDD:366402	27/107 (25%)
		PAS_11	346..448	CDD:373151	36/102 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3561
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810