Protein Alignment Clk and pasd1

DIOPT Version :9

• Sequence 1: NP_001014576.1
• Gene: Clk / 38872
• FlyBaseID: FBgn0023076
• Length: 1027
• Species: Drosophila melanogaster
• Sequence 2: XP_017951834.2
• Gene: pasd1 / 100486786
• XenbaseID: XB-GENE-1033070
• Length: 862
• Species: Xenopus tropicalis
• Alignment Length: 1059
• Identity: 336/1059 - (31%)
• Similarity: 481/1059 - (45%)
• Gaps: 262/1059 - (24%)

  Fly     1 MDDESDDKDDTKSFLCRKSRNLSEKKRRDQFNSLVNDLSALISTSSR--KMDKSTVLKSTIAFLK 63
            ||:  |:|:.||    |.|||.||||||||||.|:.:|..::....:  ||||||:|:.||.||:
 Frog     1 MDE--DEKERTK----RASRNKSEKKRRDQFNVLIKELCTMLQGHGQPLKMDKSTILQKTIDFLQ 59

  Fly    64 NHNEATDRSKVFEIQQDWKPAFLSNDEYTHLMLESLDGFMMVFSSMGSIFYASESITSQLGYLPQ 128
            ...|.|.:::..||:|||||:||||:|:|.||||:||||::..::.|.|.|.|:|::|.||:||.
 Frog    60 KQKEITAQTEACEIRQDWKPSFLSNEEFTQLMLEALDGFLIALNTDGIIIYVSDSVSSLLGHLPS 124

  Fly   129 DLYNMTIYDLAYEMDHEALLNIFMNPTPVIEPRQTD-ISSSNQITFYTHLRRGGMEKVDANAYEL 192
            |:.:..|.:...|.:...:|.:..:...:.||...: .::..|:.|..||.||.::..:...||.
 Frog   125 DMVDQNILNFLPEREQAEVLKLLASHILMTEPIIPEYFNNEKQVEFCCHLARGSLDPNEPRMYEF 189

  Fly   193 VKFVGYFRNDTNTSTGSSSEVSNGSNGQPAVLPRIFQQNPNAEVDKKLVFVGTGRVQNPQLIREM 257
            ||||..|:...|..|.|       .||..:.:.|.|:..    .::::..|.|.|:..||.::|:
 Frog   190 VKFVVDFKFCNNVPTSS-------YNGFESAVARAFRSG----TEEQICLVATVRLVTPQFLKEL 243

  Fly   258 SIIDPTSNEFTSKHSMEWKFLFLDHRAPPIIGYMPFEVLGTSGYDYYHFDDLDSIVACHEELRQT 322
            ..::....||||:||:|||||||||||||||||:||||||||||||||.|||:.:..|||.|.|.
 Frog   244 CNVEEPCEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHADDLELLARCHEHLMQC 308

  Fly   323 GEGKSCYYRFLTKGQQWIWLQTDYYVSYHQFNSKPDYVVCTHKVVSYAEVLKDSRKEGQKSGNSN 387
            |:||||||||||||||||||||.|:::|||:||||:::||||.|||||||..:.|::
 Frog   309 GKGKSCYYRFLTKGQQWIWLQTHYFITYHQWNSKPEFIVCTHTVVSYAEVRAEKRRD-------- 365

  Fly   388 SITNNGSSKVIASTGTSSKSASATTTLRDFELSSQNLDSTLLGNSLASLGTETAATSPAVDSSPM 452
                                                            ||.|.:|...:..|
 Frog   366 ------------------------------------------------LGLEESALELSETS--- 379

  Fly   453 WSASAVQPSGSCQINPLKTSRPASSYGNISSTGISPKAKRKCYFYNNRGNDSDSTSMSTDSVTSR 517
                               .:|.:::..|..|...|..:|.. ..::....|..|::| ||.::.
 Frog   380 -------------------MKPQNTFLEIRHTTQEPSRERMS-VSSHSSRISSHTALS-DSASTS 423

  Fly   518 QSMMTHVSSQSQRQRSHHREHHRENHHNQSHHHMQQQQQHQNQQQQHQQHQQLQQQLQHTVGTPK 582
            ...:|..|:.|:|                        ..:.|||:..|..
 Frog   424 SMRITEASTPSRR------------------------SLNVNQQENPQIR--------------- 449

  Fly   583 MVPLLPIASTQIMAGNACQ--FPQPAYPLASPQLVAPTFLEPPQYLTAIPMQPVIAPFPVAPVLS 645
                        ||.|:.|  .||.:....|...||.:.:.|.|.:..:...|..|.|.:.
 Frog   450 ------------MAPNSNQPGRPQVSSENLSQHHVAHSTVSPQQAIMPVYHYPNSAQFEIG---- 498

  Fly   646 PLPVQSQTDMLPDTVVMTPTQSQLQDQLQRKHDELQKLILQQQNELRIVSEQL------------ 698
                                 ..:::|||.:...||..|..||.||.::.|||
 Frog   499 ---------------------EHMKEQLQERTRMLQADIQTQQMELDVIKEQLRRMEDSNRQMPQ 542

  Fly   699 -LLSRYTYLQ---PMM----SMGFAPG---NMTAAAVGNLGASGQRGLNFTGSN-AVQPQFNQYG 751
             :...|:.||   |.|    |.| ||.   :.|..:.|.:.|.     .|..|| |||.|:  ..
 Frog   543 PIPMGYSSLQQSDPRMVSHQSSG-APRQSVDSTKKSQGMIPAK-----RFCVSNVAVQHQY--LT 599

  Fly   752 FALNSEQMLNQQDQQMMMQQQQNLHTQHQHNLQQQHQSHSQLQQHTQQQHQQQQQQQQQQQQQQQ 816
            .|.|::|.|.|...|...||.||...|.|:.||||.|  .||||..|.|.|:|||.|:||||..:
 Frog   600 PAQNTQQHLQQGPLQQQQQQPQNPLQQQQNVLQQQRQ--QQLQQKQQLQLQKQQQLQKQQQQLHK 662

  Fly   817 QQQQQQQQQQQQQQQQQQLQ-LQQQNDILLREDIDDIDAFLNL-SPLHS-----LGSQSTIN--- 871
            |||.|:|.|.|..|.|:.:: .|.|....|     .:.|..|: .||:|     ....:.:|
 Frog   663 QQQLQKQNQIQPHQHQRLIRGNQPQQTATL-----PVPAPSNIVMPLYSNTMFPQAHPTVVNSRV 722

  Fly   872 PFNSSSNNNNQSYNGGSNLNNGNQNNNNRSSNPPQNNNEDSLLSCMQMATESSPSINFHMGISDD 936
            |..:........|....:|    :.:.::...||..:.:....|.: :|.:..|:....:.|...
 Frog   723 PSETGDRQQATEYKQDRHL----RFDQDQQMRPPSLHMQPITCSTV-IAVQPPPAYTPSVMIPHS 782

  Fly   937 GSETQSEDNKMMHTSGSNLVQQQQQQQQQ-------------------QQILQQ-HQQQSNSFFS 981
            ...|| :.:..:|      |.|.||||.|                   |:|.|| |..|.::.
 Frog   783 SFSTQ-QSHASVH------VHQCQQQQVQPQHLYLQMQTQDTVQTAHSQRIFQQPHMSQQSTM-- 838

  Fly   982 SNPFLNSQNQNQNQLPNDL 1000
             ..||:.|.|||:....||
 Frog   839 -GYFLHPQQQNQSGNVTDL 856

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Clk	NP_001014576.1	HLH	16..68	CDD:238036	27/53 (51%)
		PAS	93..153	CDD:214512	22/59 (37%)
		PAS	264..366	CDD:238075	78/101 (77%)
		PAS_11	265..368	CDD:291273	79/102 (77%)
pasd1	XP_017951834.2	bHLH-PAS_PASD1	1..70	CDD:381579	35/74 (47%)
		PAS	86..>156	CDD:395786	24/69 (35%)
		PAS_11	251..354	CDD:405306	79/102 (77%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	197	1.000	Domainoid score	I3042
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	413	1.000	Inparanoid score	I1804
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002532
OrthoInspector	1	1.000	-	-		otm48926
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1900
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.050