Protein Alignment Hn and tph2

DIOPT Version :9

• Sequence 1: NP_001261542.1
• Gene: Hn / 38871
• FlyBaseID: FBgn0001208
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: XP_002940217.3
• Gene: tph2 / 100486097
• XenbaseID: XB-GENE-958329
• Length: 485
• Species: Xenopus tropicalis
• Alignment Length: 462
• Identity: 228/462 - (49%)
• Similarity: 317/462 - (68%)
• Gaps: 39/462 - (8%)

  Fly     5 QVSFDKPTRVEDSAYIVEGVDIKEARNTCLLFSPKDSSLSSGALANILAIFKKHDINLVHIESRS 69
            ::..:|.::.|.:|         |...|.::.:.|:   ..|.|...|.|||:..:|::|||||.
 Frog    41 RIDENKCSKTEATA---------ETERTAVILTMKN---EVGGLLQNLKIFKEKYVNIIHIESRK 93

  Fly    70 SL-RVPGYEFFVEADGKSGALGKAIEDVKEQCSYF-------------NIISRDYK--DNATAVP 118
            |. .....:.:||           .|..|::|...             |.:.|.::  :....|.
 Frog    94 SKGNKSEVDMYVE-----------FECTKKKCQELQHLLKLQSGIISVNPVERIWRKDEELEGVL 147

  Fly   119 WFPRRIRDLDRFANQILSYGSELDADHPGFTDPEYRKRRKYFADIAYNYKHGEPLPHVDYTKEEI 183
            ||||:|.:||:.:|::|.||||||||||||.|..||:|||||.|:|.:||:|:|:|.|:||.|||
 Frog   148 WFPRKISELDKCSNRVLMYGSELDADHPGFKDNVYRQRRKYFVDVAMDYKYGQPIPRVEYTAEEI 212

  Fly   184 ETWGIIFRNLTKLYKTHACREYNHVFPLLVDNCGFREDNIPQLEDVSNFLRDCTGFTLRPVAGLL 248
            :|||.:|:.|||||.||||:||....|||...||:||||:||||||:.||::.:|||:|||||.|
 Frog   213 KTWGTVFKELTKLYPTHACKEYLKNLPLLTKYCGYREDNVPQLEDVAIFLKERSGFTVRPVAGYL 277

  Fly   249 SSRDFLAGLAFRVFHSTQYIRHPSKPMYTPEPDVCHELMGHVPLFADPAFAQFSQEIGLASLGAP 313
            |.||||||||:||||.||||||.|.|:||||||.||||:|||||.|||.|||||||||||||||.
 Frog   278 SPRDFLAGLAYRVFHCTQYIRHGSDPLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGAS 342

  Fly   314 DDYIEKLSTIFWFTVEYGVCRQEGELKAYGAGLLSSYGELEYCLTDKPQLKDFEPEVTGVTKYPI 378
            |:.::||:|.::||:|:|:|:|:|:|:|||||||||.|||::.|:||..:|.|:|:.|.:.:..|
 Frog   343 DEDVQKLATCYFFTIEFGLCKQDGQLRAYGAGLLSSIGELKHALSDKAIVKTFDPKTTCLQECII 407

  Fly   379 TQFQPLYYVADSFETAKEKTIKFANSIPRPFGVRYNAYTQSVEVLDSKPQISNLMDNINSEFQIL 443
            |.||..|:|::||:.||||..:||.||.|||.|.:|.||||:|:|::...|.|::.::.|:...:
 Frog   408 TTFQDSYFVSESFDEAKEKMREFAKSINRPFSVYFNPYTQSIEILNNTRSIENVIQDLRSDLNTV 472

  Fly   444 QNAVAKL 450
            .:|:||:
 Frog   473 SDALAKM 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hn	NP_001261542.1	Phe4hydrox_tetr	15..451	CDD:130335	227/452 (50%)
		ACT_AAAH	32..107	CDD:153176	21/88 (24%)
		Biopterin_H	118..447	CDD:278766	198/328 (60%)
tph2	XP_002940217.3	ACT	59..132	CDD:415594	20/86 (23%)
		Biopterin_H	148..476	CDD:395280	198/327 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54212
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000587
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920