Protein Alignment KRT81 and Krt81

DIOPT Version :10

• Sequence 1: NP_002272.2
• Gene: KRT81 / 3887
• HGNCID: 6458
• Length: 505
• Species: Homo sapiens
• Sequence 2: NP_001008814.2
• Gene: Krt81 / 407761
• RGDID: 1303316
• Length: 481
• Species: Rattus norvegicus
• Alignment Length: 479
• Identity: 428/479 - (89%)
• Similarity: 456/479 - (95%)
• Gaps: 1/479 - (0%)

Human     1 MTCGSGFGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSFGY 65
            |||||||.||||||.||||||||||||||||||||||||||:|||||.||||.||:|||||||||
  Rat     1 MTCGSGFCGRAFSCASACGPRPGRCCITAAPYRGISCYRGLSGGFGSRSVCGAFRSGSCGRSFGY 65

Human    66 RSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQ 130
            ||||||||||||||||||||||||||||||||||||||.|||||||.||||||||||||||||||
  Rat    66 RSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKHEEKEQIKCLNSRFAAFIDKVRFLEQQ 130

Human   131 NKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYE 195
            |||||||.||:|||:||:||:||||||||||||||||||||||||||:||||.||.:|||||:||
  Rat   131 NKLLETKWQFFQNRKCCESNVEPLFEGYIETLRREAECVEADSGRLAAELNHAQEAMEGYKKRYE 195

Human   196 EEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEILILQSHISDTSVV 260
            |||||||||||||||||||||||||||||||||.|||.|||||||||||||..||.:|||||||:
  Rat   196 EEVSLRATAENEFVALKKDVDCAYLRKSDLEANTEALTQEIDFLRRLYEEETRILHAHISDTSVI 260

Human   261 VKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINEL 325
            ||:||||||||||:|||||||||||.:|||||||||||:||||:||||||||||||||:||||||
  Rat   261 VKMDNSRDLNMDCVIAEIKAQYDDIASRSRAEAESWYRTKCEEIKATVIRHGETLRRTREEINEL 325

Human   326 NRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQ 390
            ||:|||||||:|||||||:||||||.||||||||||:||||||||||.||||||||||||::|||
  Rat   326 NRIIQRLTAEIENAKCQNTKLEAAVTQSEQQGEAALTDARCKLAELEAALQKAKQDMACLLKEYQ 390

Human   391 EVMNSKLGLDIEIATYRRLLEGEEQRLCEGIGAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSA 455
            |||||||||||||||||.||||||||||||:||||||||||||||||||||||||||||||.|||
  Rat   391 EVMNSKLGLDIEIATYRHLLEGEEQRLCEGVGAVNVCVSSSRGGVVCGDLCVSGSRPVTGSACSA 455

Human   456 PCNGNVAVSTGLCAPCGQLNTTCG 479
            ||:||:||:||||||||.. .:||
  Rat   456 PCSGNLAVNTGLCAPCGSA-VSCG 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KRT81	NP_002272.2	Head	1..106		97/104 (93%)
		Keratin_2_head	<4..102	CDD:465068	91/97 (94%)
		Filament	105..416	CDD:459643	276/310 (89%)
		Coil 1A	107..141		31/33 (94%)
		Linker 1	142..151		6/8 (75%)
		Coil 1B	152..252		90/99 (91%)
		Linker 12	253..269		13/15 (87%)
		Coil 2	270..413		127/142 (89%)
		Tail	414..505		56/66 (85%)
Krt81	NP_001008814.2	Keratin_2_head	<3..102	CDD:465068	92/98 (94%)
		Filament	105..416	CDD:459643	276/310 (89%)