Protein Alignment Snmp2 and SCARB1

DIOPT Version :10

• Sequence 1: NP_001163372.1
• Gene: Snmp2 / 38868
• FlyBaseID: FBgn0035815
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_001354910.1
• Gene: SCARB1 / 949
• HGNCID: 1664
• Length: 552
• Species: Homo sapiens
• Alignment Length: 549
• Identity: 140/549 - (25%)
• Similarity: 232/549 - (42%)
• Gaps: 104/549 - (18%)

  Fly     4 WSLIVSALGVC---VAVLGGYCGWILFPNMVHKKVEQSVVIQDGSEQFKRFVNLPQPLNFKVYIF 65
            |:  ..||||.   .||||... .::.|:::.::|.::|.|...|..|..:..:|.|....||.|
Human     9 WA--AGALGVAGLLCAVLGAVM-IVMVPSLIKQQVLKNVRIDPSSLSFNMWKEIPIPFYLSVYFF 70

  Fly    66 NVTNSDRIQQGAIPIVEEIGPYVYKQFRQKKVKHFSRDGSKISYVQNVHFDFDAVASAPYTQDDR 130
            :|.|...|.:|..|.|.|.|||||::||.|....|:.:.: :|:::...|.|.. :.:..::.|.
Human    71 DVMNPSEILKGEKPQVRERGPYVYREFRHKSNITFNNNDT-VSFLEYRTFQFQP-SKSHGSESDY 133

  Fly   131 IVALNMHMNAFLQVFEREITDIFQGFANRLNSRLNQTPGVRVLKRLMERIRGKRKSVLQISENDP 195
            ||                                  .|.:.||            ....:.||.|
Human   134 IV----------------------------------MPNILVL------------GAAVMMENKP 152

  Fly   196 GLALLLVHLNANLKAVFNDPRSMFVSTSVREYLFDGVRFCINPQGIAKAICNQIKE--SGSKTIR 258
            ....|::.|     |........|::.:|.|.::          |....:.|.|.:  .|....:
Human   153 MTLKLIMTL-----AFTTLGERAFMNRTVGEIMW----------GYKDPLVNLINKYFPGMFPFK 202

  Fly   259 EKSDGSLAFSFFGHKNGSGHEVYEVHTGKGDPMRVLEIQKLDDSHNLQVWLNASSEGETSVCNQI 323
            :|      |..|...|.|...::.|.||..:..|:..:.|.:....:..|       .:..||.|
Human   203 DK------FGLFAELNNSDSGLFTVFTGVQNISRIHLVDKWNGLSKVDFW-------HSDQCNMI 254

  Fly   324 NGTDASAYPPFRQRGDSMYIFSADICRSVQLFYQTDIQYQGIPGYRYSIGEN-FIN-DIGPEHDN 386
            |||....:|||.....|:..:|.:.|||::|.|:....::|||.||:...:. |.| .|.|  .|
Human   255 NGTSGQMWPPFMTPESSLEFYSPEACRSMKLMYKESGVFEGIPTYRFVAPKTLFANGSIYP--PN 317

  Fly   387 ECFCVDKLANVIKRKNGCLYAGALDLTTC-LDAPVILTLPHMLGASNEYRKMIRGLKPDAKKHQT 450
            |.||            .||.:|..:::|| ..||:.|:.||.|.|.....:.:.||.|:.:.|..
Human   318 EGFC------------PCLESGIQNVSTCRFSAPLFLSHPHFLNADPVLAEAVTGLHPNQEAHSL 370

  Fly   451 FVDVQSLTGTPLQGGKRVQFNMFLKSINRIGITENLPTVLMPAIWVEEGIQLNGEMVAFFKKKLI 515
            |:|:..:||.|:....::|.::::||:..||.|..:..|::|.:|..|...:.||.:..|..:|:
Human   371 FLDIHPVTGIPMNCSVKLQLSLYMKSVAGIGQTGKIEPVVLPLLWFAESGAMEGETLHTFYTQLV 435

  Fly   516 NTLKTLNIVHWATL---CGGIGVAVACLI 541
            ...|.::...:..|   |..:.|.|.|.|
Human   436 LMPKVMHYAQYVLLALGCVLLLVPVICQI 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Snmp2	NP_001163372.1	CD36	10..543	CDD:460076	139/543 (26%)
SCARB1	NP_001354910.1	CD36	16..446	CDD:460076	130/520 (25%)