Protein Alignment NOTCH2NLA and eys

DIOPT Version :10

• Sequence 1: NP_001382160.1
• Gene: NOTCH2NLA / 388677
• HGNCID: 31862
• Length: 286
• Species: Homo sapiens
• Sequence 2: NP_001429711.1
• Gene: eys / 557044
• ZFINID: ZDB-GENE-130530-959
• Length: 2904
• Species: Danio rerio
• Alignment Length: 250
• Identity: 84/250 - (33%)
• Similarity: 128/250 - (51%)
• Gaps: 39/250 - (15%)

Human     2 CRDGY--------------EPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQ-HRDPCEKNRCQNGG 51
            |..||              .||::|.:|:....|.. |.|..||.|::|: :.|.|:.|.|:|.|
Zfish  1286 CVPGYFGPHCNLDVNECDSSPCLHESVCINKPGGFA-CVCSAGFSGKWCELNVDECKSNPCRNNG 1349

Human    52 TCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC 116
            :|:..  |....|.|:.||.|:.|:.:|.. | .|.||::|.....:  |.:.|.|:||:||..|
Zfish  1350 SCIDG--LNGYQCVCSRGFMGDHCERNTDE-C-SSGPCVHGSCLDEI--DAFSCQCEVGWTGHRC 1408

Human   117 QWT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNEC-------DIPGHCQHGGTCL 173
            |.. :.|.:|||.||.:|..:.::::|.|..||||:.|:.|.|.|       .:   |.:||||:
Zfish  1409 QININECEAHPCLNGGSCVDLLDKYACICADGFTGKNCDIDQNVCLQTSLNFSL---CFNGGTCV 1470

Human   174 NLPG-SYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQ--TGDFTFECNCLPG 225
            :.|| ::.|.|..||.|.:|:.....|...||.||..|:.  .|   ::|:|.||
Zfish  1471 DGPGVNFTCSCRPGFMGDFCEVEMNECCSEPCFNGAICQDLING---YQCHCRPG 1522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NOTCH2NLA	NP_001382160.1	EGF_CA	83..117	CDD:238011	12/33 (36%)
		EGF_CA	120..154	CDD:238011	13/33 (39%)
		EGF_CA	156..192	CDD:238011	15/43 (35%)
eys	NP_001429711.1	None