DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8492 and LYZL1

DIOPT Version :9

Sequence 1:	NP_648151.2	Gene:	CG8492 / 38866	FlyBaseID:	FBgn0035813	Length:	1360	Species:	Drosophila melanogaster
Sequence 2:	XP_005252684.1	Gene:	LYZL1 / 84569	HGNCID:	30502	Length:	185	Species:	Homo sapiens

Alignment Length:	133	Identity:	45/133 - (33%)
Similarity:	66/133 - (49%)	Gaps:	33/133 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   439 KVYNRCELAQ-------ELYFSHKFPMQDLATWVCIAEHESSFNTTAVGRLNADGSADHGLFQIS 496
            |:|.||:||:       :.|:..     .|..|:|:|.:||.:||||...|: |||.|:|:|||:
Human    66 KIYTRCKLAKIFSRAGLDNYWGF-----SLGNWICMAYYESGYNTTAQTVLD-DGSIDYGIFQIN 124

  Fly   497 DLYWCTHNDGGGK-----GCHIDCNRLLDSDITDDVKCVRTIHEEHTRISGDGFTAWTV------ 550
            ...||..    ||     .||:.|:.|:..|:||.:.|.|.|.:|     ..|...|::
Human   125 SFAWCRR----GKLKENNHCHVACSALITDDLTDAIICARKIVKE-----TQGMNYWSLLLRIPN 180

  Fly   551 YNG 553
            |.|
Human   181 YKG 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8492	NP_648151.2	LYZ1	18..142	CDD:238066
		LYZ1	185..312	CDD:238066
		LYZ1	439..566	CDD:238066	45/133 (34%)
		LYZ1	596..723	CDD:238066
		PARM	937..>1068	CDD:293666
LYZL1	XP_005252684.1	LYZ1	66..172	CDD:238066	42/120 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1551203at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm41688
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.920