DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8492 and SPACA5B

DIOPT Version :9

Sequence 1:	NP_648151.2	Gene:	CG8492 / 38866	FlyBaseID:	FBgn0035813	Length:	1360	Species:	Drosophila melanogaster
Sequence 2:	NP_001073369.1	Gene:	SPACA5B / 729201	HGNCID:	19142	Length:	159	Species:	Homo sapiens

Alignment Length:	136	Identity:	51/136 - (37%)
Similarity:	77/136 - (56%)	Gaps:	10/136 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   592 TPKAKIYNRCELAKELYHR--HKFPMREIPTWVCIAEHESSFNTAAVGKLNADGSEDHGLFQISD 654
            |..||||.|||||..|...  :.:....:..|:|:|.:||.|:||.|.. |.|||.::|:||::.
Human    18 TVDAKIYERCELAARLERAGLNGYKGYGVGDWLCMAHYESGFDTAFVDH-NPDGSSEYGIFQLNS 81

  Fly   655 IYWCTHDQTSGK-ACHIECDRLLDSDISDDVQCIRTIHEEHTRLSGDGFNAWTVYNGHCRNQNLA 718
            .:||.:..|..| .||::|..||:..|.||::|.:.|..     |.:|.:|||.:..||...:|:
Human    82 AWWCDNGITPTKNLCHMDCHDLLNRHILDDIRCAKQIVS-----SQNGLSAWTSWRLHCSGHDLS 141

  Fly   719 K-LSDC 723
            : |..|
Human   142 EWLKGC 147

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8492	NP_648151.2	LYZ1	18..142	CDD:238066
		LYZ1	185..312	CDD:238066
		LYZ1	439..566	CDD:238066
		LYZ1	596..723	CDD:238066	48/130 (37%)
		PARM	937..>1068	CDD:293666
SPACA5B	NP_001073369.1	LYZ_C	22..147	CDD:340383	48/130 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153986
Domainoid	1	1.000	88	1.000	Domainoid score	I7920
eggNOG	1	0.900	-	-		E1_2BPI7
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1551203at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm41688
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.750