DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8492 and LYZL6

DIOPT Version :9

Sequence 1:	NP_648151.2	Gene:	CG8492 / 38866	FlyBaseID:	FBgn0035813	Length:	1360	Species:	Drosophila melanogaster
Sequence 2:	NP_001186880.1	Gene:	LYZL6 / 57151	HGNCID:	29614	Length:	148	Species:	Homo sapiens

Alignment Length:	128	Identity:	44/128 - (34%)
Similarity:	69/128 - (53%)	Gaps:	11/128 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   594 KAKIYNRCELAK--ELYHRHKFPMREIPTWVCIAEHESSFNTAAVGKLNADGSEDHGLFQISDIY 656
            :|.:.:||:||:  :|.....|....:..|:|:|..||.||.:.:.: |||||.|:|||||:..|
Human    18 QASLISRCDLAQVLQLEDLDGFEGYSLSDWLCLAFVESKFNISKINE-NADGSFDYGLFQINSHY 81

  Fly   657 WCT-HDQTSGKACHIECDRLLDSDISDDVQCIRTIHEEHTRLSG-DGFNAWTVYNGHCRNQNL 717
            ||. :...|...||::|..||:.::...:.|.:.|      :|| .|.|.|..:..||..:.|
Human    82 WCNDYKSYSENLCHVDCQDLLNPNLLAGIHCAKRI------VSGARGMNNWVEWRLHCSGRPL 138

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8492	NP_648151.2	LYZ1	18..142	CDD:238066
		LYZ1	185..312	CDD:238066
		LYZ1	439..566	CDD:238066
		LYZ1	596..723	CDD:238066	43/126 (34%)
		PARM	937..>1068	CDD:293666
LYZL6	NP_001186880.1	LYZ1	22..142	CDD:238066	43/124 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153925
Domainoid	1	1.000	88	1.000	Domainoid score	I7920
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1551203at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm41688
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850