DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8492 and LYZ

DIOPT Version :9

Sequence 1:	NP_648151.2	Gene:	CG8492 / 38866	FlyBaseID:	FBgn0035813	Length:	1360	Species:	Drosophila melanogaster
Sequence 2:	NP_000230.1	Gene:	LYZ / 4069	HGNCID:	6740	Length:	148	Species:	Homo sapiens

Alignment Length:	144	Identity:	53/144 - (36%)
Similarity:	76/144 - (52%)	Gaps:	13/144 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LLLPLLATAKIFDRCELANLLQHRFGLP---AAQVATLVCIAQHSSDFNTAAFGGGVGLGGGSHG 70
            :||.:....|:|:|||||..|: |.|:.   ...:|..:|:|:..|.:||.|.....|.....:|
Human    10 VLLSVTVQGKVFERCELARTLK-RLGMDGYRGISLANWMCLAKWESGYNTRATNYNAGDRSTDYG 73

  Fly    71 LFQISDVYWCS---PPGQGKGCGLSCSRLRDDDIADDVLCVRKIYAEHQRISGDGFTAWQAYDAY 132
            :|||:..|||:   .||....|.||||.|..|:|||.|.|.:::..:.|     |..||.|:...
Human    74 IFQINSRYWCNDGKTPGAVNACHLSCSALLQDNIADAVACAKRVVRDPQ-----GIRAWVAWRNR 133

  Fly   133 CR-QDANSYVAGCG 145
            |: :|...||.|||
Human   134 CQNRDVRQYVQGCG 147

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8492	NP_648151.2	LYZ1	18..142	CDD:238066	47/130 (36%)
		LYZ1	185..312	CDD:238066
		LYZ1	439..566	CDD:238066
		LYZ1	596..723	CDD:238066
		PARM	937..>1068	CDD:293666
LYZ	NP_000230.1	LYZ1	19..147	CDD:197612	49/133 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2BPI7
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1551203at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm41688
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820