DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8492 and LALBA

DIOPT Version :9

Sequence 1:	NP_648151.2	Gene:	CG8492 / 38866	FlyBaseID:	FBgn0035813	Length:	1360	Species:	Drosophila melanogaster
Sequence 2:	NP_001371279.1	Gene:	LALBA / 3906	HGNCID:	6480	Length:	142	Species:	Homo sapiens

Alignment Length:	139	Identity:	44/139 - (31%)
Similarity:	67/139 - (48%)	Gaps:	12/139 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VVCLLLPLLATAKIFDRCELANLLQHRFGLPAAQVATLVCIAQHSSDFNTAAFGGGVGLGGGSHG 70
            :|.:|.|.: .||.|.:|||:.||:...|.....:..|:|...|:|.::|.|.  ........:|
Human     9 LVGILFPAI-LAKQFTKCELSQLLKDIDGYGGIALPELICTMFHTSGYDTQAI--VENNESTEYG 70

  Fly    71 LFQISDVYWCSP---PGQGKGCGLSCSRLRDDDIADDVLCVRKIYAEHQRISGDGFTAWQAYDAY 132
            |||||:..||..   |.....|.:||.:..||||.||::|.:||      :...|...|.|:.|.
Human    71 LFQISNKLWCKSSQVPQSRNICDISCDKFLDDDITDDIMCAKKI------LDIKGIDYWLAHKAL 129

  Fly   133 CRQDANSYV 141
            |.:....::
Human   130 CTEKLEQWL 138

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8492	NP_648151.2	LYZ1	18..142	CDD:238066	40/127 (31%)
		LYZ1	185..312	CDD:238066
		LYZ1	439..566	CDD:238066
		LYZ1	596..723	CDD:238066
		PARM	937..>1068	CDD:293666
LALBA	NP_001371279.1	Lys	20..138	CDD:395016	40/125 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153985
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2BPI7
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1551203at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	5	4.710