DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7457 and SPIK

DIOPT Version :9

Sequence 1:	NP_001303376.1	Gene:	CG7457 / 38865	FlyBaseID:	FBgn0035812	Length:	1405	Species:	Drosophila melanogaster
Sequence 2:	NP_180131.3	Gene:	SPIK / 817099	AraportID:	AT2G25600	Length:	888	Species:	Arabidopsis thaliana

Alignment Length:	322	Identity:	75/322 - (23%)
Similarity:	117/322 - (36%)	Gaps:	99/322 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   384 LNQDAPSEAFTTLCTIAEIC------------EQQSHPFWTVHDVYQKALRQADKAGSCSDKLVK 436
            |..:||::.:..:....:|.            .|:.|.|..|..:..:.               :
plant   427 LQNEAPTDFYILVTGAVDIIARVNGVEQVVSEAQRGHVFGEVGVLCYRP---------------Q 476

  Fly   437 IAMVRLRRL--MLKHNMQVLVENLEADATAKGIDLDQEESVGDDEEESDGGGTAVQ----QNTPD 495
            :..||.:||  :|:.|..||:..::|             :|||        |..:.    |:..|
plant   477 LFTVRTKRLSQLLRLNRTVLLNLVQA-------------NVGD--------GAIIMNNLLQHLKD 520

  Fly   496 WDDDFDLATLTDSDASDLDETEKPRP----------------QRTTRGNRTLVIKKNNKGETQLH 544
            .:|......|.|::.. |.:.:...|                |...||:....:.|:  |.|.||
plant   521 SEDPVMKGVLADTEHM-LAQGKMDLPLSLCFAAARGDDLLLHQLLRRGSSPNEMDKD--GRTALH 582

  Fly   545 QACISGNLELVRRLIDQGHTVNVRDHAGWLPLHEACNHGYREIVELLLDKGA------------- 596
            .|...|:...|..|::.|...|:||..|.:||.||....:|||.:||.:.||
plant   583 IAASKGSHYCVVLLLEHGADPNIRDSEGNVPLWEAIIGRHREIAKLLAENGAKLSLDSVSYFSGL 647

  Fly   597 ------ASAIND---KGG----TSCDGITPLFDACSNGFLDVAELLLDRGADATVRTDYNET 645
                  ..|:.|   .||    ...:|.|.|..|.|.|.|::.:.|||:|||......|..|
plant   648 AVEKNCLDALKDIIKYGGDVTLPDGNGTTALHRAVSEGHLEIVKFLLDQGADLDWPDSYGWT 709

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7457	NP_001303376.1	TPR_12	21..95	CDD:290160
		TPR	68..387	CDD:223533	1/2 (50%)
		TPR repeat	163..191	CDD:276809
		TPR repeat	196..233	CDD:276809
		TPR repeat	238..273	CDD:276809
		TPR repeat	316..342	CDD:276809
		TPR repeat	347..384	CDD:276809	75/322 (23%)
		TPR repeat	389..422	CDD:276809	6/44 (14%)
		ANK	535..647	CDD:238125	44/137 (32%)
		ANK repeat	539..569	CDD:293786	10/29 (34%)
		Ank_2	543..639	CDD:289560	39/121 (32%)
		ANK repeat	571..604	CDD:293786	14/54 (26%)
		ANK repeat	609..639	CDD:293786	13/29 (45%)
		LRR_RI	1063..1360	CDD:238064
		leucine-rich repeat	1088..1115	CDD:275381
		leucine-rich repeat	1116..1170	CDD:275381
		leucine-rich repeat	1199..1225	CDD:275381
		leucine-rich repeat	1226..1261	CDD:275381
		leucine-rich repeat	1262..1289	CDD:275381
		leucine-rich repeat	1290..1315	CDD:275381
SPIK	NP_180131.3	PLN03192	38..888	CDD:215625	75/322 (23%)
		ANK repeat	548..574	CDD:293786	3/25 (12%)
		ANK repeat	576..607	CDD:293786	10/32 (31%)
		ANK repeat	609..671	CDD:293786	16/61 (26%)
		ANK repeat	673..704	CDD:293786	13/30 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000