DRSC/TRiP Functional Genomics Resources

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Protein Alignment GBP7 and LOC100488013

DIOPT Version :10

Sequence 1:NP_997281.2 Gene:GBP7 / 388646 HGNCID:29606 Length:638 Species:Homo sapiens
Sequence 2:XP_012823014.1 Gene:LOC100488013 / 100488013 XenbaseID:XB-GENE-29079035 Length:657 Species:Xenopus tropicalis


Alignment Length:98 Identity:22/98 - (22%)
Similarity:36/98 - (36%) Gaps:27/98 - (27%)


- Green bases have known domain annotations that are detailed below.


Human    12 LCEEWPVDETKRGRDLGAYLRQRVAQAFREGENTQIAEPEACDQMYESLARLHSNYYKHKYPRPR 76
            :.|:..||..|.|.||..|           |...|..:|...|...|....|.:||.     :..
 Frog   223 ILEDDLVDSCKSGDDLTIY-----------GIVMQRWKPFQQDVRCEVEIVLKANYI-----QVN 271

Human    77 DTSFSGLSVEEYKLILSTDTLEEFQEMNKSMWK 109
            :...||:.::|       :..:||::    .|:
 Frog   272 NEQSSGIIMDE-------EVQKEFED----FWE 293

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GBP7NP_997281.2 GTPase domain (Globular). /evidence=ECO:0000250|UniProtKB:P32455 1..310 22/98 (22%)
GBP 18..281 CDD:460516 21/92 (23%)
GBP_C 283..579 CDD:460721
Interaction with the CYBA-CYBB complex. /evidence=ECO:0000250|UniProtKB:Q91Z40 311..638
C-terminal tail, required for its localization to cytoplasmic vesicle. /evidence=ECO:0000250|UniProtKB:Q91Z40 590..638
LOC100488013XP_012823014.1 GBP 47..312 CDD:460516 22/98 (22%)
GBP_C 314..601 CDD:460721
Blue background indicates that the domain is not in the aligned region.

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