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Protein Alignment Mcad and Ivd

DIOPT Version :9

Sequence 1:	NP_648149.1	Gene:	Mcad / 38864	FlyBaseID:	FBgn0035811	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_062800.1	Gene:	Ivd / 56357	MGIID:	1929242	Length:	424	Species:	Mus musculus

Alignment Length:	402	Identity:	137/402 - (34%)
Similarity:	205/402 - (50%)	Gaps:	48/402 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 NGTSFALTEDQLQLQELARKFTREEIIPVAAQYDKSGEYP-----WPIIKKAWELGLMNNHIPAD 90
            ||    |.|:|.||:....||.:|.:.|.|.:.|::.::.     |   |:...||::....|..
Mouse    41 NG----LNEEQKQLRHTISKFLQENLAPKAQEIDQTNDFKNLREFW---KQLGSLGVLGITAPVQ 98

  Fly    91 IGGLDLDVFTTCLSAEEL--AYGCTGIMTALEASGLGQTPVILSGNKEQKKKYLGRLLEEPLVAA 153
            .||..|......|..||:  |.|..|:..... |.|....::.:||:.||:|||.:|:....:.|
Mouse    99 YGGSGLGYLEHVLVMEEISRASGAVGLSYGAH-SNLCVNQIVRNGNEAQKEKYLPKLISGEFIGA 162

  Fly   154 YCVTEPGAGSDVSGIKTRAEKKGDEWVINGQKMWITNGGVANWYFVLARTNPDPKCPPSKAFTGF 218
            ..::||.|||||..:|.:||||||.:|:||.|.|||||..|:...|.|:|:. ...|.|:..|.|
Mouse   163 LAMSEPNAGSDVVSMKLKAEKKGDHYVLNGNKFWITNGPDADILVVYAKTDL-TAVPASRGITAF 226

  Fly   219 IVERDSPGLTPGRKELNMGQRASDTRGITFEDVRVPKENVLIGEGAGFKIAMGTFDKTRPPVAAG 283
            |||:..||.:..:|...:|.|.|:|..:.|||.:||..|||..|..|..:.|...|..|..:|.|
Mouse   227 IVEKGMPGFSTSKKLDKLGMRGSNTCELVFEDCKVPAANVLSQESKGVYVLMSGLDLERLVLAGG 291

  Fly   284 AVGLAQRCLDEALKYALERKTFGVPIAYHQAVQFMLADMAIGVETSRLAWRLSAWEIDQGRRNSY 348
            .:|:.|..||..:.|...|:.||..|...|.:|..:|||...:..||                .|
Mouse   292 PLGIMQAVLDHTIPYLHVREAFGQKIGQFQLMQGKMADMYTRLMASR----------------QY 340

  Fly   349 YASIAKC----------------HAADMANKIASDAVQIFGGNGFNSEYPVEKLMRDAKIYQIYE 397
            ..::||.                :||:.|.::|.|.:|..||||:.:::|:.:.:||||:|:|..
Mouse   341 VYNVAKACDEGHIIPKDCAGVILYAAECATQVALDGIQCLGGNGYINDFPMGRFLRDAKLYEIGA 405

  Fly   398 GTSQIQRLIISR 409
            |||:::||:|.|
Mouse   406 GTSEVRRLVIGR 417

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.