DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Mcad and Acox1

DIOPT Version :9

Sequence 1:	NP_648149.1	Gene:	Mcad / 38864	FlyBaseID:	FBgn0035811	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_059036.1	Gene:	Acox1 / 50681	RGDID:	619757	Length:	661	Species:	Rattus norvegicus

Alignment Length:	344	Identity:	82/344 - (23%)
Similarity:	139/344 - (40%)	Gaps:	88/344 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 PALRQLVSQSRAYAA-----VSHV---SPNGT-------SFALTEDQLQLQELARKFTREEIIPV 59
            |.||    :.||.|.     ::|:   ||..|       :..|.:...|.::. ...||.:...|
  Rat     3 PDLR----KERASATFNPELITHILDGSPENTRRRREIENLILNDPDFQHEDY-NFLTRSQRYEV 62

  Fly    60 AAQYDKSGEYPWPIIKKAWELGLMNNHIPADIGGLDLDVFTTCLSAEELAYGCTGIMTALEASGL 124
            |.:  ||.    .::||..|.|:.:   |.:|                :.:....:...:|..||
  Rat    63 AVK--KSA----TMVKKMREYGISD---PEEI----------------MWFKKLYLANFVEPVGL 102

  Fly   125 GQT---PVILS-GNKEQKKKYLGRLLEEPLVAAYCVTEPGAGSDVSGIKTRA--EKKGDEWVING 183
            ..:   |.:|: |...|::|::....|..::..|..||.|.|:.:.|::|.|  :.|..|:::|.
  Rat   103 NYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNS 167

  Fly   184 Q-----KMWITNGGV---ANWYFVLARTNPDPKCPPSKAFTGFIVE----RDSPGLTPGRKELNM 236
            .     |.|  .||:   :|...|||:.....:|....||...|.|    :..||:|.|......
  Rat   168 PTVTSIKWW--PGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKF 230

  Fly   237 GQRASDTRGITFEDVRVPKENVLIGEGAGFKIAM----GTFDK---------TRPPVAAGAVGLA 288
            |....|...:..::.|:|:||:|:      |.|.    ||:.|         |...|.:..||.|
  Rat   231 GYEEMDNGYLKMDNYRIPRENMLM------KYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNA 289

  Fly   289 QRCLDE----ALKYALERK 303
            .:.|.:    |::|:..|:
  Rat   290 AQSLSKACTIAIRYSAVRR 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mcad	NP_648149.1	CaiA	35..411	CDD:224871	72/304 (24%)
Mcad	NP_648149.1	MCAD	37..414	CDD:173846	72/302 (24%)
Acox1	NP_059036.1	AXO	3..638	CDD:173839	82/344 (24%)
Acox1	NP_059036.1	Microbody targeting signal	659..661
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900