DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mcad and acadsb

DIOPT Version :9

Sequence 1:	NP_648149.1	Gene:	Mcad / 38864	FlyBaseID:	FBgn0035811	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	XP_031760846.1	Gene:	acadsb / 448259	XenbaseID:	XB-GENE-1005696	Length:	429	Species:	Xenopus tropicalis

Alignment Length:	422	Identity:	141/422 - (33%)
Similarity:	224/422 - (53%)	Gaps:	26/422 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KLAAPALRQLVSQSRAYAAVSH------VSP------NGTSFA----LTEDQLQLQELARKFTRE 54
            :|...::||.:..|:   ||||      ..|      .|..:|    .||::..::|:.:|:.:|
Frog    10 QLLGRSIRQSICGSQ---AVSHRWQSSVADPLDQALREGAIYAPLQTFTEEETMIKEMVKKYAQE 71

  Fly    55 EIIPVAAQYDKSGEYPWPIIKKAWELGLMNNHIPADIGGLDLDVFTTCLSAEELAY--GCTGIMT 117
            .|.|:....|.:.:....:|:..:|||||...:....||.....|::.|..||||.  ....:|.
Frog    72 RIAPLVKTMDANSKMDNSVIEGLFELGLMGVEVDPKYGGTGASFFSSILVIEELARVDPSVSVMC 136

  Fly   118 ALEASGLGQTPVILSGNKEQKKKYLGRLLEEPLVAAYCVTEPGAGSDVSGIKTRAEKKGDEWVIN 182
            .:: :.|..|.....|.::||:.||.||..: .|.::|::|..:|||...::|.|:|..|.::||
Frog   137 DIQ-NTLINTLFQRLGTEQQKETYLPRLCRD-TVGSFCLSEAESGSDAFSLRTSAQKHKDYYIIN 199

  Fly   183 GQKMWITNGGVANWYFVLARTNPDPKCPPSKAFTGFIVERDSPGLTPGRKELNMGQRASDTRGIT 247
            |.||||:|...|..:.|:|..||.   ...|..|.|||.:|:.|...|:||..:|.|||.|..:|
Frog   200 GSKMWISNSEQAGVFLVMANANPS---AGYKGITCFIVPKDTEGFHIGKKEDKLGLRASSTCSLT 261

  Fly   248 FEDVRVPKENVLIGEGAGFKIAMGTFDKTRPPVAAGAVGLAQRCLDEALKYALERKTFGVPIAYH 312
            |::|:||:.|:|...|.|:|.|:|..::.|..::|..:||||.|.|..:.|..:|..||..|...
Frog   262 FDNVKVPESNILGQLGHGYKYAIGMLNEGRIGISAQMLGLAQGCFDHTIPYTKQRVQFGKRIFDF 326

  Fly   313 QAVQFMLADMAIGVETSRLAWRLSAWEIDQGRRNSYYASIAKCHAADMANKIASDAVQIFGGNGF 377
            |.:|..::.:|..:|.:||....:|...:.||.....|.:||..::::|....|..::..||.|:
Frog   327 QGMQHQISHVATQLEATRLLTYNAARLKEAGRDFKKEACMAKYFSSEVACLTTSKCIEWMGGVGY 391

  Fly   378 NSEYPVEKLMRDAKIYQIYEGTSQIQRLIISR 409
            ..:||:||..|||||..||||||.||...|::
Frog   392 TKDYPIEKYYRDAKIGTIYEGTSNIQLSTIAK 423

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mcad	NP_648149.1	CaiA	35..411	CDD:224871	131/381 (34%)
Mcad	NP_648149.1	MCAD	37..414	CDD:173846	130/375 (35%)
acadsb	XP_031760846.1	SCAD_SBCAD	56..425	CDD:173847	129/373 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D589058at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010