Protein Alignment Mcad and ACADM

DIOPT Version :10

• Sequence 1: NP_648149.1
• Gene: Mcad / 38864
• FlyBaseID: FBgn0035811
• Length: 419
• Species: Drosophila melanogaster
• Sequence 2: NP_001272972.1
• Gene: ACADM / 34
• HGNCID: 89
• Length: 454
• Species: Homo sapiens
• Alignment Length: 444
• Identity: 286/444 - (64%)
• Similarity: 338/444 - (76%)
• Gaps: 40/444 - (9%)

  Fly    13 RQLVSQSRAYAAVSHVSPN-------GTSFALTEDQLQLQELARKFTREEIIPVAAQYDKSGEYP 70
            |.|.|.||.:....|...|       |.||..||.|.:.|..||||.|||||||||:|||:||||
Human    10 RVLRSISRFHWRSQHTKANRQREPGLGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYP 74

  Fly    71 WPIIKKAWELGLMNNHIP---------------------------------ADIGGLDLDVFTTC 102
            .|:|::||||||||.|||                                 .::|||.|..|..|
Human    75 VPLIRRAWELGLMNTHIPENCDYSVCPLLEACTLYLDAFFLLLTGSNLNLHLNLGGLGLGTFDAC 139

  Fly   103 LSAEELAYGCTGIMTALEASGLGQTPVILSGNKEQKKKYLGRLLEEPLVAAYCVTEPGAGSDVSG 167
            |.:|||||||||:.||:|.:.|||.|:|::||.:||||||||:.||||:.|||||||||||||:|
Human   140 LISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAG 204

  Fly   168 IKTRAEKKGDEWVINGQKMWITNGGVANWYFVLARTNPDPKCPPSKAFTGFIVERDSPGLTPGRK 232
            |||:|||||||::||||||||||||.|||||:|||::||||.|.:|||||||||.|:||:..|||
Human   205 IKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRK 269

  Fly   233 ELNMGQRASDTRGITFEDVRVPKENVLIGEGAGFKIAMGTFDKTRPPVAAGAVGLAQRCLDEALK 297
            |||||||.||||||.||||:|||||||||:|||||:|||.||||||.|||||||||||.||||.|
Human   270 ELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATK 334

  Fly   298 YALERKTFGVPIAYHQAVQFMLADMAIGVETSRLAWRLSAWEIDQGRRNSYYASIAKCHAADMAN 362
            |||||||||..:..|||:.||||:||:.||.:|::::.:|||:|.||||:|||||||..|.|:||
Human   335 YALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIAN 399

  Fly   363 KIASDAVQIFGGNGFNSEYPVEKLMRDAKIYQIYEGTSQIQRLIISRNMYEAAK 416
            ::|:|||||.||||||:|||||||||||||||||||||||||||::|...:..|
Human   400 QLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHIDKYK 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcad	NP_648149.1	MCAD	37..414	CDD:173846	275/409 (67%)
ACADM	NP_001272972.1	MCAD	41..451	CDD:173846	275/409 (67%)