Protein Alignment Mcad and ACAD9

DIOPT Version :9

• Sequence 1: NP_648149.1
• Gene: Mcad / 38864
• FlyBaseID: FBgn0035811
• Length: 419
• Species: Drosophila melanogaster
• Sequence 2: NP_054768.2
• Gene: ACAD9 / 28976
• HGNCID: 21497
• Length: 621
• Species: Homo sapiens
• Alignment Length: 437
• Identity: 142/437 - (32%)
• Similarity: 225/437 - (51%)
• Gaps: 48/437 - (10%)

  Fly     8 AAPALRQLVSQSRAYAAVSHVSPNGTSFA------------------LTEDQL----QLQELARK 50
            ||.|.|.|| .|.|...:...||...:||                  :::|:|    |......|
Human    13 AARACRGLV-VSTANRRLLRTSPPVRAFAKELFLGKIKKKEVFPFPEVSQDELNEINQFLGPVEK 76

  Fly    51 FTREEIIPVAAQYDKSGEYPWPIIKKAWELGLMNNHIPADIGGLDLDVFTTCLSAEELAYGCTGI 115
            |..||:  .:.:.|:.|:.|...::|...|||....:|.:.|||.   |:..:      |...|.
Human    77 FFTEEV--DSRKIDQEGKIPDETLEKLKSLGLFGLQVPEEYGGLG---FSNTM------YSRLGE 130

  Fly   116 MTALEAS---------GLGQTPVILSGNKEQKKKYLGRLLEEPLVAAYCVTEPGAGSDVSGIKTR 171
            :.:::.|         .:|...:||:|.:|||.|||.:|.....:||:|:|||.:|||.:.|::|
Human   131 IISMDGSITVTLAAHQAIGLKGIILAGTEEQKAKYLPKLASGEHIAAFCLTEPASGSDAASIRSR 195

  Fly   172 AEKKGDE--WVINGQKMWITNGGVANWYFVLARTN-PDPKCPPSKAFTGFIVERDSPGLTPGRKE 233
            |....|:  :::||.|:||||||:||.:.|.|:|. .|.........|.||||||..|:|.|:.|
Human   196 ATLSEDKKHYILNGSKVWITNGGLANIFTVFAKTEVVDSDGSVKDKITAFIVERDFGGVTNGKPE 260

  Fly   234 LNMGQRASDTRGITFEDVRVPKENVLIGEGAGFKIAMGTFDKTRPPVAAGAVGLAQRCLDEALKY 298
            ..:|.|.|:|..:.||:.::|.||:|...|.|||:||...:..|..:.:...||.:|.::...:|
Human   261 DKLGIRGSNTCEVHFENTKIPVENILGEVGDGFKVAMNILNSGRFSMGSVVAGLLKRLIEMTAEY 325

  Fly   299 ALERKTFGVPIAYHQAVQFMLADMAIGVETSRLAWRLSAWEIDQ-GRRN-SYYASIAKCHAADMA 361
            |..||.|...::....:|...|.||...........|:|..:|| |..: |..|::.|..:::.|
Human   326 ACTRKQFNKRLSEFGLIQEKFALMAQKAYVMESMTYLTAGMLDQPGFPDCSIEAAMVKVFSSEAA 390

  Fly   362 NKIASDAVQIFGGNGFNSEYPVEKLMRDAKIYQIYEGTSQIQRLIIS 408
            .:..|:|:||.||.|:..:||.|:::||.:|..|:|||::|.|:.|:
Human   391 WQCVSEALQILGGLGYTRDYPYERILRDTRILLIFEGTNEILRMYIA 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcad	NP_648149.1	CaiA	35..411	CDD:224871	132/410 (32%)
		MCAD	37..414	CDD:173846	130/390 (33%)
ACAD9	NP_054768.2	VLCAD	38..445	CDD:173850	132/411 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810