Protein Alignment Mcad and acdh-2

DIOPT Version :10

• Sequence 1: NP_648149.1
• Gene: Mcad / 38864
• FlyBaseID: FBgn0035811
• Length: 419
• Species: Drosophila melanogaster
• Sequence 2: NP_001343623.1
• Gene: acdh-2 / 173940
• WormBaseID: WBGene00015894
• Length: 386
• Species: Caenorhabditis elegans
• Alignment Length: 403
• Identity: 117/403 - (29%)
• Similarity: 190/403 - (47%)
• Gaps: 53/403 - (13%)

  Fly    23 AAVSHVSPNGTSFA-----------LTEDQLQLQELARKFTREEIIPVAAQYDKSGEYPWPIIKK 76
            :|:|..|..|:..|           |.|::.:|.|..:.|.:..:.|:..:.|:.......::||
 Worm    11 SAISTFSTTGSISAQQQPRVFPLQHLNENEKKLVEKVKNFAQSSVKPLVREMDRDARINKQLLKK 75

  Fly    77 AWELGLMNNHIPADIGGLDLDVFTTCLSAEELAYGCTGIMTALEASGLGQTPVILS-GNKEQKKK 140
            |::|.||...|....||..:..|...|:.|||:.....|...:........|:|.. ||:|.|:|
 Worm    76 AFDLKLMGLKIDPKYGGSGVSFFELVLAVEELSKIDPAIALIMHLQNALVAPLIEEFGNEELKEK 140

  Fly   141 YLGRLLEEPLVAAYCVTEPGAGSDVSGIKTRAEKKGDEWVINGQKMWITNGGVANWYFVLARTNP 205
            ||.:|.::. |.|:.::|..:|||...::|.|:|.||.:::||.|..|:|..:|:::.|||..:|
 Worm   141 YLKKLCKDS-VGAFALSEVVSGSDAFAMQTVAKKDGDHFILNGSKWGISNAPIADFFLVLANADP 204

  Fly   206 DPKCPPSKAFTG---FIVERDSPGLTPGRKELNMGQRASDTRGITFEDVRVPKENVLIGE-GAGF 266
            :      |.:.|   |||:||..|:..|.::.|:|.||.....:....|||||.:: :|| |.|:
 Worm   205 E------KGYRGVTCFIVDRDHEGVVLGEQDDNLGMRAGTIAQVHLNSVRVPKTSI-VGEYGKGY 262

  Fly   267 KIAMGTFDKTRPPVAAGAVGLAQRCLDEALKYALERKTFGVPIAYHQAVQFMLADMAIGVETSRL 331
            |.|:...:.:|                             :.|.....:|..:|.:...:|.:||
 Worm   263 KYAIEVLNASR-----------------------------IVIGAQMGLQHQIAKIQTEIEAARL 298

  Fly   332 AWRLSAWEIDQGRRNSYYASIAKCHAADMANKIASDAVQIFGGNGFNSEYPVEKLMRDAKIYQIY 396
            .....|...|.|......||:||.:|.::|.|.....::..||.||...:..||..|||.:..||
 Worm   299 MVYNCARMKDCGMPFVKEASMAKYYAPEVACKTTKQCIEWLGGVGFTKNFMAEKFYRDAVVGGIY 363

  Fly   397 EGTSQIQRLIISR 409
            ||||.||...|::
 Worm   364 EGTSNIQLNTIAK 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcad	NP_648149.1	MCAD	37..414	CDD:173846	112/378 (30%)
acdh-2	NP_001343623.1	ACAD	38..379	CDD:447864	111/376 (30%)