DRSC/TRiP Functional Genomics Resources

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Protein Alignment Mcad and Arc42

DIOPT Version :10

Sequence 1:NP_648149.1 Gene:Mcad / 38864 FlyBaseID:FBgn0035811 Length:419 Species:Drosophila melanogaster
Sequence 2:XP_321112.6 Gene:Arc42 / 1281174 VectorBaseID:AGAMI1_013418 Length:404 Species:Anopheles gambiae


Alignment Length:412 Identity:162/412 - (39%)
Similarity:237/412 - (57%) Gaps:21/412 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MAFLNKLAAPALRQLVSQSRAYAAVSHVSPNGTSFALTEDQLQLQELARKFTREEIIPVAAQYDK 65
            |.|..::|: .:.|.| :||:.|::|         ||.:....||:..|.|...|::|.||::|:
Mosquito     1 MMFAVRIAS-RMGQRV-RSRSIASLS---------ALPDTHQMLQKTCRDFADNELVPNAARFDR 54

  Fly    66 SGEYPWPIIKKAWELGLMNNHIPADIGGLDLDVFTTCLSAEELAYGCTG---IMTALEASGLGQT 127
            ...||...|:|..|||||...:..:.||..||.....::.||::.||..   ||:...:..||  
Mosquito    55 EHLYPAEQIRKMGELGLMAISVKEEYGGTGLDYVAYAIAMEEISRGCASAGVIMSVNNSLYLG-- 117

  Fly   128 PVILSGNKEQKKKYLGRLLEEPLVAAYCVTEPGAGSDVSGIKTRAEKKGDEWVINGQKMWITNGG 192
            |:...||::|::||:....:...|..:.::|||.|||.....|.|..|||.||:||.|.|||||.
Mosquito   118 PLTHFGNEQQQQKYVAEYTDGSRVGCFALSEPGNGSDAGAASTTATLKGDHWVLNGTKCWITNGY 182

  Fly   193 VANWYFVLARTNPDPKCPPSKAFTGFIVERDSPGLTPGRKELNMGQRASDTRGITFEDVRVPKEN 257
            .|....|.|.|:...|   .|..:.|||.:::||.:.|:||..:|.|.|.|..:.|||..:|:||
Mosquito   183 EAGAAVVFATTDKSLK---HKGISAFIVPKETPGFSLGKKEDKLGIRGSSTCSLIFEDCAIPREN 244

  Fly   258 VLIGEGAGFKIAMGTFDKTRPPVAAGAVGLAQRCLDEALKYALERKTFGVPIAYHQAVQFMLADM 322
            :|...|.||||||.|.|..|..:|:.|:|:||..|:.|:.||.:|..||.|||..||:|..:|||
Mosquito   245 LLGEPGFGFKIAMQTLDAGRIGIASQALGIAQASLECAVDYANKRIAFGKPIAKLQAIQTKIADM 309

  Fly   323 AIGVETSR-LAWRLSAWEIDQGRRNSYYASIAKCHAADMANKIASDAVQIFGGNGFNSEYPVEKL 386
            |..:|.:| |.|| :||..|..:..:..|:.||..|::.|...|..::|:.||.|:.|:.|.|:.
Mosquito   310 ATRLEAARLLTWR-AAWLKDNKKPFTKEAAQAKLAASEAATYCAHQSIQVLGGMGYVSDMPAERH 373

  Fly   387 MRDAKIYQIYEGTSQIQRLIIS 408
            .|||:|.:||||||:||||:|:
Mosquito   374 YRDARITEIYEGTSEIQRLVIA 395

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
McadNP_648149.1 MCAD 37..414 CDD:173846 152/376 (40%)
Arc42XP_321112.6 None

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