DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ank2 and AT1G34050

DIOPT Version :9

Sequence 1:	NP_001189070.1	Gene:	Ank2 / 38863	FlyBaseID:	FBgn0261788	Length:	13559	Species:	Drosophila melanogaster
Sequence 2:	NP_174667.1	Gene:	AT1G34050 / 840302	AraportID:	AT1G34050	Length:	573	Species:	Arabidopsis thaliana

Alignment Length:	504	Identity:	129/504 - (25%)
Similarity:	204/504 - (40%)	Gaps:	114/504 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   462 VDA-RAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMY-------TALHIAAKEGQDEVA 518
            :|| .|.:..|.|.:|.  ||:.::              ::.|       |.||:|.:.|..|:.
plant    22 IDAILANDVSTLLALAE--GNLSVL--------------RERYHWDSLGGTVLHLATELGHKEIV 70

  Fly   519 AVLIENGAALDAATK-KGFTPLHLTAKYGHIK-VAQLLLQKEADVDAQGKNGVTPLHVACHYNNQ 581
            ..:|:...:|...|. .|.||||..|::||.. |||:|....|:.......|.|...|||.|.|.
plant    71 EAIIKLCPSLVGVTNLDGDTPLHFAARWGHATIVAQILASGYAEFTPVNGRGETAFVVACRYTNP 135

  Fly   582 QVALLLLEKGASP-----HATAKNGHTPLHIAARKNQMDIATTLLE-YGALA-NAESKAGFTPLH 639
            .||.|:||:.:|.     :||...|          ...|||..:|| :..|| ||:.:.. ||||
plant   136 DVASLILEETSSITIGEFYATFVLG----------EYTDIARRMLERFPKLAWNADGELS-TPLH 189

  Fly   640 LSSQEGHAEISNLLIE-HKAAVNHPAKNGLTPMHLCAQEDNVNV-AEILEKNGANIDMATKAGYT 702
            .:....:.||:.:|:| .::......|:|.||:||.|.:.::.: .|..:|.....|:.|.|..|
plant   190 HACNANNLEITKMLLEIDESLAERVNKDGFTPLHLAAMKCSIPILKEFSDKAPRYFDILTPAKET 254

  Fly   703 PLHVASHFGQANMVRFLLQNGA--------NVDAATSIGYTPLHQTAQQGHCH--IVNLLLEHKA 757
            ..|:|:.  ..|::.|.....:        .||   ..|.|.|| ||....|:  ||::..|...
plant   255 VFHLAAE--HKNILAFYFMAESPDRNNLLHQVD---RYGNTVLH-TAVMSSCYSVIVSITYETTI 313

  Fly   758 NANAQTVNGQTPLHIARKLGYISVLDSLKTITKEDETAAAPSQAEEKYRVVAPEAMHESFMSDSE 822
            :.:|:...|               |.::..|..:||..:..|      |.:..:|.....:||..
plant   314 DLSAKNNRG---------------LKAVDLINVDDEDYSKIS------RWLRFDAKQIRSLSDPN 357

  Fly   823 EEGGEDNMLSDQPYRYLTVDEMKSLGDDSLPIDVTRDERMDSNRMTQSAEYASGVPPTIGEEVIS 887
            .:.|..||.....|:.:.:.|..|..:..:..:...:.|   |.:|..|...:.|..|.|   |:
plant   358 HQQGNKNMGVLSEYKKMQIFETPSKRESKMHAEALLNAR---NTITIVAVLIASVAFTCG---IN 416

  Fly   888 PHKTQVYGSSPKATVDGVYIANGSGHDEPPH-----VGRKLSWKSFLVS 931
            |             ..|||       .|.|:     .||.|:::.|.:|
plant   417 P-------------PGGVY-------QEGPYKGKSTAGRTLAFQVFSIS 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ank2	NP_001189070.1	ANK repeat	10..41	CDD:293786
		Ank_4	11..64	CDD:290365
		ANK	38..163	CDD:238125
		ANK repeat	43..74	CDD:293786
		Ank_2	48..135	CDD:289560
		ANK repeat	76..107	CDD:293786
		ANK repeat	109..134	CDD:293786
		Ank_4	110..163	CDD:290365
		Ank_4	172..225	CDD:290365
		ANK repeat	175..202	CDD:293786
		ANK	199..324	CDD:238125
		ANK repeat	204..235	CDD:293786
		Ank_2	209..300	CDD:289560
		ANK repeat	237..268	CDD:293786
		ANK	266..390	CDD:238125
		ANK repeat	270..300	CDD:293786
		ANK repeat	303..367	CDD:293786
		Ank_2	308..399	CDD:289560
		ANK	364..489	CDD:238125	8/27 (30%)
		ANK repeat	369..400	CDD:293786
		ANK repeat	402..433	CDD:293786
		Ank_4	403..456	CDD:290365
		ANK repeat	435..466	CDD:293786	2/4 (50%)
		Ank_2	440..530	CDD:289560	17/75 (23%)
		ANK	463..588	CDD:238125	41/134 (31%)
		ANK repeat	468..497	CDD:293786	5/28 (18%)
		ANK repeat	501..530	CDD:293786	9/35 (26%)
		Ank_2	506..597	CDD:289560	34/97 (35%)
		ANK	529..654	CDD:238125	45/133 (34%)
		ANK repeat	535..565	CDD:293786	13/30 (43%)
		ANK repeat	567..598	CDD:293786	14/35 (40%)
		Ank_2	572..661	CDD:289560	31/96 (32%)
		ANK repeat	600..630	CDD:293786	9/31 (29%)
		ANK repeat	633..662	CDD:293786	8/29 (28%)
		ANK	661..785	CDD:238125	32/134 (24%)
		ANK repeat	666..697	CDD:293786	9/31 (29%)
		Ank_2	672..762	CDD:289560	25/100 (25%)
		ANK repeat	699..730	CDD:293786	8/38 (21%)
		ANK repeat	732..762	CDD:293786	10/31 (32%)
		ZU5	927..1030	CDD:128514	2/5 (40%)
		Death_ank	1417..1497	CDD:260029
		ER-remodelling	11936..>12013	CDD:258892
AT1G34050	NP_174667.1	ANK repeat	20..51	CDD:293786	9/44 (20%)
		ANK	51..204	CDD:238125	53/163 (33%)
		ANK repeat	54..85	CDD:293786	8/30 (27%)
		Ank_2	58..150	CDD:289560	34/91 (37%)
		ANK repeat	87..119	CDD:293786	13/31 (42%)
		ANK repeat	121..181	CDD:293786	24/69 (35%)
		Ank_5	169..225	CDD:290568	19/56 (34%)
		ANK	181..304	CDD:238125	34/129 (26%)
		Ank_2	188..304	CDD:289560	32/121 (26%)
		PGG	390..499	CDD:290670	19/82 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1011028at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1009
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920