DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ank2 and AT1G07710

DIOPT Version :9

Sequence 1:	NP_001189070.1	Gene:	Ank2 / 38863	FlyBaseID:	FBgn0261788	Length:	13559	Species:	Drosophila melanogaster
Sequence 2:	NP_001318946.1	Gene:	AT1G07710 / 837285	AraportID:	AT1G07710	Length:	543	Species:	Arabidopsis thaliana

Alignment Length:	506	Identity:	130/506 - (25%)
Similarity:	214/506 - (42%)	Gaps:	116/506 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   372 TPLHIACKK-NRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVR 435
            |.||.|.:. |:.:|||:|.:       |.||.|..|     :|..|                ..
plant    29 TLLHSAVRHGNKDRVVEILTK-------TRESELNQL-----LGKQN----------------QS 65

  Fly   436 GETPLHLAARANQTDIIRILLR--NGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDAT 498
            |||.|::||.....:|::.::.  :.|.|:.:||......|||::.|::|::.:|.:..::: |.
plant    66 GETALYVAAEYGDVEIVKEMINCYDLALVEIKARNGFDAFHIAAKQGDLDVLKVLAEAHSEL-AM 129

  Fly   499 TKDM--YTALHIAAKEGQDEVAAVLIENGAALDAATK-KGFTPLHLTAKYGHIKVAQLLLQKEAD 560
            |.|:  .||||.||.:|..||...|:|.|::|....| .|.|.||..::.||:||.:.||..|..
plant   130 TVDLSNTTALHTAATQGHTEVVNFLLELGSSLAGIAKSNGKTALHSASRNGHVKVIKALLASEPA 194

  Fly   561 VDAQ-GKNGVTPLHVACHYNNQQVA--LLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLE 622
            :..: .|.|.|.||:|....|.:|.  |:..::.:...|..| |:|.|||||||.:..|...|
plant   195 IAIRMDKKGQTALHMAVKGTNVEVVEELIKADRSSINIADTK-GNTALHIAARKGRSQIVKLL-- 256

  Fly   623 YGALAN------AESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVN 681
               |||      |.:::|.|.|..:.:.|:.|::.:|.:|..    |:...:.|       ...|
plant   257 ---LANNMTDTKAVNRSGETALDTAEKIGNPEVALILQKHGV----PSAKTIKP-------SGPN 307

  Fly   682 VAEILEKNGANI--DMATKAGYTPLHVASHFGQANMVRFLLQNGAN--VDAATSIGYTPLHQTAQ 742
            .|..|::..::|  ::..:..:|.|......|.|..:..:...|.|  :::.|
plant   308 PARELKQTVSDIKHEVHNQLEHTRLTRKRVQGIAKQLNKMHTEGLNNAINSTT------------ 360

  Fly   743 QGHCHIVNLLLEHKANANAQTVNGQ----------------------TPLHIARKLGYISVLDSL 785
                 :|.:|:...|.|...||.||                      ||..|......|::..||
plant   361 -----VVAVLIATVAFAAIFTVPGQYVEDTSKIPDGHSLGEANIASTTPFIIFFIFDSIALFISL 420

  Fly   786 KTITKEDETAAAPSQAEEKYRVVAPEAM------------HESFMSDSEEE 824
            ..:..:.......|:|:::...|..:.|            ..||:...|||
plant   421 AVVVVQTSVVVIESKAKKQMMAVINKLMWLACVLISVAFLALSFVVVGEEE 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ank2	NP_001189070.1	ANK repeat	10..41	CDD:293786
		Ank_4	11..64	CDD:290365
		ANK	38..163	CDD:238125
		ANK repeat	43..74	CDD:293786
		Ank_2	48..135	CDD:289560
		ANK repeat	76..107	CDD:293786
		ANK repeat	109..134	CDD:293786
		Ank_4	110..163	CDD:290365
		Ank_4	172..225	CDD:290365
		ANK repeat	175..202	CDD:293786
		ANK	199..324	CDD:238125
		ANK repeat	204..235	CDD:293786
		Ank_2	209..300	CDD:289560
		ANK repeat	237..268	CDD:293786
		ANK	266..390	CDD:238125	8/18 (44%)
		ANK repeat	270..300	CDD:293786
		ANK repeat	303..367	CDD:293786
		Ank_2	308..399	CDD:289560	9/27 (33%)
		ANK	364..489	CDD:238125	32/119 (27%)
		ANK repeat	369..400	CDD:293786	9/28 (32%)
		ANK repeat	402..433	CDD:293786	5/30 (17%)
		Ank_4	403..456	CDD:290365	11/52 (21%)
		ANK repeat	435..466	CDD:293786	9/32 (28%)
		Ank_2	440..530	CDD:289560	30/93 (32%)
		ANK	463..588	CDD:238125	45/130 (35%)
		ANK repeat	468..497	CDD:293786	6/28 (21%)
		ANK repeat	501..530	CDD:293786	14/30 (47%)
		Ank_2	506..597	CDD:289560	32/94 (34%)
		ANK	529..654	CDD:238125	43/134 (32%)
		ANK repeat	535..565	CDD:293786	11/30 (37%)
		ANK repeat	567..598	CDD:293786	9/32 (28%)
		Ank_2	572..661	CDD:289560	30/96 (31%)
		ANK repeat	600..630	CDD:293786	14/35 (40%)
		ANK repeat	633..662	CDD:293786	7/28 (25%)
		ANK	661..785	CDD:238125	25/149 (17%)
		ANK repeat	666..697	CDD:293786	5/32 (16%)
		Ank_2	672..762	CDD:289560	15/93 (16%)
		ANK repeat	699..730	CDD:293786	6/32 (19%)
		ANK repeat	732..762	CDD:293786	4/29 (14%)
		ZU5	927..1030	CDD:128514
		Death_ank	1417..1497	CDD:260029
		ER-remodelling	11936..>12013	CDD:258892
AT1G07710	NP_001318946.1	ANK repeat	26..63	CDD:293786	15/45 (33%)
		Ank_2	31..127	CDD:372319	32/123 (26%)
		ANK repeat	65..98	CDD:293786	9/32 (28%)
		ANK repeat	100..132	CDD:293786	8/32 (25%)
		ANKYR	108..312	CDD:223738	69/221 (31%)
		ANK repeat	134..166	CDD:293786	13/31 (42%)
		ANK repeat	168..200	CDD:293786	11/31 (35%)
		ANK repeat	202..234	CDD:293786	8/31 (26%)
		ANK repeat	270..294	CDD:293786	6/23 (26%)
		PGG	349..466	CDD:372845	23/133 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1009
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910