DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ank2 and AT5G54710

DIOPT Version :9

Sequence 1:	NP_001189070.1	Gene:	Ank2 / 38863	FlyBaseID:	FBgn0261788	Length:	13559	Species:	Drosophila melanogaster
Sequence 2:	NP_001332664.1	Gene:	AT5G54710 / 835560	AraportID:	AT5G54710	Length:	643	Species:	Arabidopsis thaliana

Alignment Length:	648	Identity:	144/648 - (22%)
Similarity:	256/648 - (39%)	Gaps:	156/648 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   383 LKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTV--RGETPLHLAAR 445
            :|:::|.   .:.:|.|...|.||||:||.:|..:|:..:|:...: |...:  :|:|...||..
plant     1 MKIIDLC---PSLVSVTNVDGNTPLHLAAEIGNESILWKMLRCGRA-DCMKINKQGQTAFILACL 61

  Fly   446 ANQTDIIRILLRN-----GAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTA 505
            .|..|....|:.|     ..::||....|| |:.|...|.....::|      .||   ::..|.
plant    62 NNHLDAALTLVENMRSMTMVELDAAFTGQQ-PVIIDKMLEKFPSLVL------DVD---EEQSTL 116

  Fly   506 LHIAAKEGQDEVAAVLIENGAALDAATK-KGFTPLHLTAKYGHIKVAQLLLQK-EADVDAQGKNG 568
            ||.|..:..:|.|..:|:...:|.:.|. .|.|||||.|:.|:|.:...:|:. ||:.....|.|
plant   117 LHKAVTQRNEEYATKVIDLCPSLVSVTNVDGNTPLHLAAEIGNINILWKMLETGEAECMKINKQG 181

  Fly   569 VTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEY--GALANAES 631
            .|...:||..||...|.:|:|      .|:......|:.|..:.|..|..::||.  ..:.:|:.
plant   182 QTAFILACLNNNVNSARILVE------GTSSMTMVELNAAFSEQQQVIIDSILEKFPNLILDADE 240

  Fly   632 KAGFTPLHLSSQEGHAEISNLLIE---HKAAVNHPAKNGLTPMHLCAQEDNVNV-AEILEKNGAN 692
            :.. |.||.:.:.|:.|::..|::   ::.......|:||||:|......:|.: .|.|.|..::
plant   241 EQS-TLLHKACKSGNLEMARTLLDVDVNQEIAEKVDKDGLTPLHRAVINGSVEILKEFLCKAPSS 304

  Fly   693 IDMATKAGY-TPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHK 756
            .::.|:... |..|:|:.:.:.....|:.|:                       .:|..||....
plant   305 FNITTQGTIETVFHLAAKYQKTKAFIFMAQS-----------------------ANIRQLLYSLD 346

  Fly   757 ANANAQTVNGQTPLHIARKLGYISVLDSLKTITKEDETAAAPSQAEEKYRVVAPEAMHESFMSDS 821
            |..|       |.||:|..:...|::..:.:.|..|.|      .:.|....|.:.:
plant   347 AEDN-------TVLHVAASVDSTSLVRHILSETTIDVT------LKNKKGFAAVDLI-------- 390

  Fly   822 EEEGGEDNMLS----------DQPYRYL-----------TVDEMKSLGDDSLPIDVTRDERMDSN 865
            ::||.:..:||          .:|.||:           ..:..:.|..:|..:|:.|:.|...|
plant   391 DKEGVDFPLLSLWFRDEAEKIQRPARYVKFAHEPVELIRNTNNGEKLSSESRAMDLLREGRDPRN 455

  Fly   866 RMTQSAEYASGVPPTIGEEVISPHKTQVYGSSPKATVDGVYIAN----------GSGHDEPPHV- 919
            :..:.                  |...:..:....|:..|.||:          |..|.:.|.:
plant   456 KEREM------------------HSESLQNARNTITIVAVLIASVAFTCGINPPGGVHQDGPFIG 502

  Fly   920 ----GRKLSWKSF-----------------LVSFLVDARGGAMRGC---RHSGVRMIIPSRST 958
                ||.|::|.|                 ||| ::..|..|::.|   .|..:.:.:.|.:|
plant   503 KATAGRTLAFKIFSVANNIALFTSLSIVTLLVS-IISYRTKALKMCVVIAHKMMWLAVASMAT 564

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ank2	NP_001189070.1	ANK repeat	10..41	CDD:293786
		Ank_4	11..64	CDD:290365
		ANK	38..163	CDD:238125
		ANK repeat	43..74	CDD:293786
		Ank_2	48..135	CDD:289560
		ANK repeat	76..107	CDD:293786
		ANK repeat	109..134	CDD:293786
		Ank_4	110..163	CDD:290365
		Ank_4	172..225	CDD:290365
		ANK repeat	175..202	CDD:293786
		ANK	199..324	CDD:238125
		ANK repeat	204..235	CDD:293786
		Ank_2	209..300	CDD:289560
		ANK repeat	237..268	CDD:293786
		ANK	266..390	CDD:238125	2/6 (33%)
		ANK repeat	270..300	CDD:293786
		ANK repeat	303..367	CDD:293786
		Ank_2	308..399	CDD:289560	3/15 (20%)
		ANK	364..489	CDD:238125	31/112 (28%)
		ANK repeat	369..400	CDD:293786	3/16 (19%)
		ANK repeat	402..433	CDD:293786	11/30 (37%)
		Ank_4	403..456	CDD:290365	17/54 (31%)
		ANK repeat	435..466	CDD:293786	10/35 (29%)
		Ank_2	440..530	CDD:289560	24/94 (26%)
		ANK	463..588	CDD:238125	39/126 (31%)
		ANK repeat	468..497	CDD:293786	7/28 (25%)
		ANK repeat	501..530	CDD:293786	8/28 (29%)
		Ank_2	506..597	CDD:289560	30/92 (33%)
		ANK	529..654	CDD:238125	36/128 (28%)
		ANK repeat	535..565	CDD:293786	12/30 (40%)
		ANK repeat	567..598	CDD:293786	9/30 (30%)
		Ank_2	572..661	CDD:289560	21/93 (23%)
		ANK repeat	600..630	CDD:293786	6/31 (19%)
		ANK repeat	633..662	CDD:293786	6/31 (19%)
		ANK	661..785	CDD:238125	26/125 (21%)
		ANK repeat	666..697	CDD:293786	9/31 (29%)
		Ank_2	672..762	CDD:289560	16/91 (18%)
		ANK repeat	699..730	CDD:293786	5/31 (16%)
		ANK repeat	732..762	CDD:293786	5/29 (17%)
		ZU5	927..1030	CDD:128514	10/52 (19%)
		Death_ank	1417..1497	CDD:260029
		ER-remodelling	11936..>12013	CDD:258892
AT5G54710	NP_001332664.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1011028at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1009
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920