DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ank2 and AT3G09550

DIOPT Version :9

Sequence 1:	NP_001189070.1	Gene:	Ank2 / 38863	FlyBaseID:	FBgn0261788	Length:	13559	Species:	Drosophila melanogaster
Sequence 2:	NP_001325606.1	Gene:	AT3G09550 / 820112	AraportID:	AT3G09550	Length:	614	Species:	Arabidopsis thaliana

Alignment Length:	591	Identity:	136/591 - (23%)
Similarity:	224/591 - (37%)	Gaps:	146/591 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   380 KNRL---KVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLH 441
            |.|:   |.:|..:..|.:...|:.:|.|   ||               |.|| .||.|....|.
plant     9 KKRIEEEKELEPGMEKGLATDPTSPTGST---VA---------------DLSP-TPTPRKTLVLS 54

  Fly   442 LAARA----NQTDIIRILLRNGAQVD----------ARAREQQTPLHIASRLGNV-DIVMLLLQH 491
            .:.:|    |.:..:. |..:|.:.|          ...|...|.||:|::.|:: .:..:|...
plant    55 NSGKALMVSNSSKSLG-LSNSGKRFDPTGKKKYVKQVTGRHNDTELHLAAQRGDLASVKQILSDI 118

  Fly   492 GAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQ 556
            .:|:..|         |...:..||||.::.   :.::...:.|.|||...|:.|:|.|.:.||.
plant   119 DSQITGT---------ITGADFDDEVAQIMT---SVVNEVNELGETPLFTAAEKGNIDVVKELLP 171

  Fly   557 KEADVDAQGKN--GVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATT 619
            .........||  |...||:||...::.:..||||            |.|
plant   172 YTTIESLMQKNLSGFDALHIACSQGHRSIVQLLLE------------HEP--------------- 209

  Fly   620 LLEYGALANAESKAGFTPLHLSSQEGHAEISN-LLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVA 683
                 .|:...:::..|||..::..||:|:.| ||.:..:.:.....||...:||.|::.:|::.
plant   210 -----QLSKTVAQSNATPLVSAATRGHSEVVNELLAKDSSLLEISRSNGKNALHLAARQGHVDIV 269

  Fly   684 E-ILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQ-NGANVDAATSIGYTPLHQTAQQGHC 746
            . :|:|:........|.|.|.||:|.....:.:||.||: :.|.|......|.|.||...::...
plant   270 RTLLDKDPQLARRTDKKGQTSLHMAVKGVSSQVVRLLLRADPAIVMLPDKFGNTVLHIATRKKRA 334

  Fly   747 HIVNLLLE-HKANANAQTVNGQTPLHIARKLGYISVLDSLKTITKEDETAAAPSQAEEKYRVVAP 810
            .|||.||: ...|.||.|.:.:|...||..|            |..:|||
plant   335 EIVNELLQLPDTNVNALTRDHKTAYDIAEGL------------THSEETA--------------- 372

  Fly   811 EAMHESFMSDSEEEGGEDNMLSDQPYRYLTVDEMKSLGDDSLPIDVTR--DERMDSNRMTQSAEY 873
             .:.|........:..|.|...|:..:  ||.|:|.  |....::.||  ::.:|.
plant   373 -EIKEILSRCGALKANELNQPRDELRK--TVTEIKK--DVHTQLEQTRKTNKNVDG--------- 423

  Fly   874 ASGVPPTIGEEVISPHKTQVYGSSPKATVDGVYIANGS--------GHDEPPHVGRKLSWKSFLV 930
                   |.:|:...|:..:..::...||..|..|..:        |.|:...|...:...||.:
plant   424 -------IAKELRKLHRAGINNATNSVTVVAVLFATVAFAAIFTVPGGDDDHGVAVMVHATSFKI 481

  Fly   931 SFLVDA 936
            .|:.:|
plant   482 FFIFNA 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ank2	NP_001189070.1	ANK repeat	10..41	CDD:293786
		Ank_4	11..64	CDD:290365
		ANK	38..163	CDD:238125
		ANK repeat	43..74	CDD:293786
		Ank_2	48..135	CDD:289560
		ANK repeat	76..107	CDD:293786
		ANK repeat	109..134	CDD:293786
		Ank_4	110..163	CDD:290365
		Ank_4	172..225	CDD:290365
		ANK repeat	175..202	CDD:293786
		ANK	199..324	CDD:238125
		ANK repeat	204..235	CDD:293786
		Ank_2	209..300	CDD:289560
		ANK repeat	237..268	CDD:293786
		ANK	266..390	CDD:238125	4/12 (33%)
		ANK repeat	270..300	CDD:293786
		ANK repeat	303..367	CDD:293786
		Ank_2	308..399	CDD:289560	5/21 (24%)
		ANK	364..489	CDD:238125	28/126 (22%)
		ANK repeat	369..400	CDD:293786	5/22 (23%)
		ANK repeat	402..433	CDD:293786	7/30 (23%)
		Ank_4	403..456	CDD:290365	13/56 (23%)
		ANK repeat	435..466	CDD:293786	7/44 (16%)
		Ank_2	440..530	CDD:289560	20/104 (19%)
		ANK	463..588	CDD:238125	33/137 (24%)
		ANK repeat	468..497	CDD:293786	7/29 (24%)
		ANK repeat	501..530	CDD:293786	5/28 (18%)
		Ank_2	506..597	CDD:289560	26/92 (28%)
		ANK	529..654	CDD:238125	32/127 (25%)
		ANK repeat	535..565	CDD:293786	10/29 (34%)
		ANK repeat	567..598	CDD:293786	10/32 (31%)
		Ank_2	572..661	CDD:289560	20/89 (22%)
		ANK repeat	600..630	CDD:293786	3/29 (10%)
		ANK repeat	633..662	CDD:293786	9/29 (31%)
		ANK	661..785	CDD:238125	37/126 (29%)
		ANK repeat	666..697	CDD:293786	8/31 (26%)
		Ank_2	672..762	CDD:289560	29/92 (32%)
		ANK repeat	699..730	CDD:293786	11/31 (35%)
		ANK repeat	732..762	CDD:293786	11/30 (37%)
		ZU5	927..1030	CDD:128514	4/10 (40%)
		Death_ank	1417..1497	CDD:260029
		ER-remodelling	11936..>12013	CDD:258892
AT3G09550	NP_001325606.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1009
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910