DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ank2 and Ankrd61

DIOPT Version :9

Sequence 1:NP_001189070.1 Gene:Ank2 / 38863 FlyBaseID:FBgn0261788 Length:13559 Species:Drosophila melanogaster
Sequence 2:NP_001037762.1 Gene:Ankrd61 / 689907 RGDID:1586393 Length:418 Species:Rattus norvegicus


Alignment Length:351 Identity:102/351 - (29%)
Similarity:153/351 - (43%) Gaps:73/351 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   339 TALH-------VAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASI 396
            ||||       :...|..:|.    |.||...|       .||.:.......:.          :
  Rat    26 TALHSRLYEAIIKEDCDTIRT----LLRNHPVN-------QPLTLLASSTGYRF----------L 69

  Fly   397 SATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHL---------------AARA 446
            |..|:. :.|:|:||.......::.||||.|.|:|...:|.|.|||               :.|.
  Rat    70 SQQTQP-IFPIHLAAEYRKPQSLLCLLQHGADPEVRDAQGLTTLHLMLLNWPVTSTTWTKPSTRI 133

  Fly   447 NQ--TDI-------IRILLRNGAQVDARA--REQQTPLHIASRLGNVDIVMLLLQHGAQVDATTK 500
            .:  |||       :|||..:||||:||.  ..:.:|||:|...|...::..|.|:||||:|..:
  Rat   134 QKILTDIQNNAVLCLRILCDHGAQVNARVDNSNKHSPLHLAITYGTYPVLSFLAQNGAQVNAINE 198

  Fly   501 DMYTALHIAAKEGQDEVAAVLIENGAALDAA-TKKGFTPLHL-----TAKYGHIKVA-----QLL 554
            ...|.||:||......:...||..||.::.| :..|.|.|.|     ::|.|.:..|     :||
  Rat   199 SSMTPLHMAADILNKNMIETLIACGANVNCAISSTGNTALKLAVCTASSKAGRLLAAGVGCIRLL 263

  Fly   555 LQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATT 619
            |...|.|:||...|.|.||.||....:.:..||||..|:.:...:||.:|:::..:::......|
  Rat   264 LNHGAQVNAQDHEGQTALHEACFGGREVIINLLLEFEANVNILTRNGESPIYMYLQRSSNIRDVT 328

  Fly   620 LLEYGALANAESKAGFTPLHLSSQEG 645
            ||       |.......||.||:::|
  Rat   329 LL-------ARLLYRTYPLRLSNKQG 347

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ank2NP_001189070.1 ANK repeat 10..41 CDD:293786
Ank_4 11..64 CDD:290365
ANK 38..163 CDD:238125
ANK repeat 43..74 CDD:293786
Ank_2 48..135 CDD:289560
ANK repeat 76..107 CDD:293786
ANK repeat 109..134 CDD:293786
Ank_4 110..163 CDD:290365
Ank_4 172..225 CDD:290365
ANK repeat 175..202 CDD:293786
ANK 199..324 CDD:238125
ANK repeat 204..235 CDD:293786
Ank_2 209..300 CDD:289560
ANK repeat 237..268 CDD:293786
ANK 266..390 CDD:238125 12/57 (21%)
ANK repeat 270..300 CDD:293786
ANK repeat 303..367 CDD:293786 10/34 (29%)
Ank_2 308..399 CDD:289560 13/66 (20%)
ANK 364..489 CDD:238125 39/150 (26%)
ANK repeat 369..400 CDD:293786 3/30 (10%)
ANK repeat 402..433 CDD:293786 11/30 (37%)
Ank_4 403..456 CDD:290365 22/76 (29%)
ANK repeat 435..466 CDD:293786 17/54 (31%)
Ank_2 440..530 CDD:289560 37/115 (32%)
ANK 463..588 CDD:238125 45/137 (33%)
ANK repeat 468..497 CDD:293786 11/28 (39%)
ANK repeat 501..530 CDD:293786 9/28 (32%)
Ank_2 506..597 CDD:289560 34/101 (34%)
ANK 529..654 CDD:238125 38/128 (30%)
ANK repeat 535..565 CDD:293786 13/39 (33%)
ANK repeat 567..598 CDD:293786 11/30 (37%)
Ank_2 572..661 CDD:289560 21/74 (28%)
ANK repeat 600..630 CDD:293786 6/29 (21%)
ANK repeat 633..662 CDD:293786 5/13 (38%)
ANK 661..785 CDD:238125
ANK repeat 666..697 CDD:293786
Ank_2 672..762 CDD:289560
ANK repeat 699..730 CDD:293786
ANK repeat 732..762 CDD:293786
ZU5 927..1030 CDD:128514
Death_ank 1417..1497 CDD:260029
ER-remodelling 11936..>12013 CDD:258892
Ankrd61NP_001037762.1 ANK 1 27..57 9/40 (23%)
ANK 29..114 CDD:238125 25/106 (24%)
ANK 2 74..103 10/29 (34%)
ANK 78..220 CDD:238125 46/141 (33%)
ANK repeat 78..105 CDD:293786 11/26 (42%)
Ank_2 79..197 CDD:289560 40/117 (34%)
ANK repeat 107..164 CDD:293786 18/56 (32%)
ANK 3 131..160 11/28 (39%)
ANK 164..297 CDD:238125 43/132 (33%)
ANK 4 166..195 11/28 (39%)
ANK repeat 168..197 CDD:293786 12/28 (43%)
Ank_2 171..274 CDD:289560 34/102 (33%)
ANK repeat 199..274 CDD:293786 23/74 (31%)
ANK 5 199..228 9/28 (32%)
ANK 6 233..272 12/38 (32%)
Ank_5 263..316 CDD:290568 20/52 (38%)
ANK repeat 276..305 CDD:293786 11/28 (39%)
ANK 7 276..305 11/28 (39%)
ANK 8 309..342 9/39 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4177
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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