DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ank2 and pyx

DIOPT Version :9

Sequence 1:NP_001189070.1 Gene:Ank2 / 38863 FlyBaseID:FBgn0261788 Length:13559 Species:Drosophila melanogaster
Sequence 2:NP_612015.1 Gene:pyx / 38037 FlyBaseID:FBgn0035113 Length:956 Species:Drosophila melanogaster


Alignment Length:442 Identity:120/442 - (27%)
Similarity:188/442 - (42%) Gaps:67/442 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly   287 VDMLLERGAPISAKTKNGL----APLHMAAQGEH-----VDAARILLYHRAPVDEVTVD------ 336
            ||:||::.:..|.....|:    |....|.|.::     :|..:..| ..:|..:..||      
  Fly    25 VDLLLDKRSISSEANSAGVFSDEAHEIFARQQQNQILWDLDEVKETL-TESPGGKHVVDMVQSGC 88

  Fly   337 YLTALHVAAHC----------GHVRVAKLLLDR-NADANARALNGFTPLHIACKKNRLKVVELLL 390
            :|..:..:|.|          |.|.....||.. |||.|.....|.||||.||.:....:.::||
  Fly    89 FLELMTDSADCNLALICCSVFGSVENTLFLLKHYNADPNVADSRGRTPLHFACCRANAPIAKVLL 153

  Fly   391 RHGASISA-TTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRI 454
            ..||..:. .....:|.||.||....:..::.||:..||.:: .:...:.||.|...|..|.:.|
  Fly   154 DFGADPNRWDARKEVTSLHCAASSKSVECILLLLRRKASINI-GIEKRSALHYAIDVNAVDCVEI 217

  Fly   455 LLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAA 519
            ||:.||..:......:||||.||..|....|.|||.|.|.|             .::.|:.:|  
  Fly   218 LLKYGADPNTPQVYTETPLHTASAAGFAKCVQLLLSHNADV-------------RSQFGEGKV-- 267

  Fly   520 VLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVA 584
                             |.|||.|:..:::.|:|||:..|:||.:..:..||||:||...:....
  Fly   268 -----------------TALHLAAENDYVECARLLLEHRAEVDCRNASHQTPLHLACLSQSIGTV 315

  Fly   585 LLLLEKGASPHATAKNGHTPLH--IAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHA 647
            .||:..||:.:|..::|.|.||  |..:...:|....||:.||..|.....|:||||:::....:
  Fly   316 DLLISYGANVNAVYRDGRTALHAAIVKQSRSLDCCNALLKAGADVNKADNYGYTPLHIAALNEFS 380

  Fly   648 EISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKA 699
            ......|||.|.:.......::.:....:    ...||:.|....:|.:.||
  Fly   381 SCVYTFIEHGADITARTDGRVSALSFIVR----RTPEIIPKLMQKLDSSIKA 428

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ank2NP_001189070.1 ANK repeat 10..41 CDD:293786
Ank_4 11..64 CDD:290365
ANK 38..163 CDD:238125
ANK repeat 43..74 CDD:293786
Ank_2 48..135 CDD:289560
ANK repeat 76..107 CDD:293786
ANK repeat 109..134 CDD:293786
Ank_4 110..163 CDD:290365
Ank_4 172..225 CDD:290365
ANK repeat 175..202 CDD:293786
ANK 199..324 CDD:238125 10/45 (22%)
ANK repeat 204..235 CDD:293786
Ank_2 209..300 CDD:289560 5/12 (42%)
ANK repeat 237..268 CDD:293786
ANK 266..390 CDD:238125 32/128 (25%)
ANK repeat 270..300 CDD:293786 5/12 (42%)
ANK repeat 303..367 CDD:293786 20/89 (22%)
Ank_2 308..399 CDD:289560 29/113 (26%)
ANK 364..489 CDD:238125 40/125 (32%)
ANK repeat 369..400 CDD:293786 11/31 (35%)
ANK repeat 402..433 CDD:293786 9/30 (30%)
Ank_4 403..456 CDD:290365 15/52 (29%)
ANK repeat 435..466 CDD:293786 10/30 (33%)
Ank_2 440..530 CDD:289560 26/89 (29%)
ANK 463..588 CDD:238125 35/124 (28%)
ANK repeat 468..497 CDD:293786 14/28 (50%)
ANK repeat 501..530 CDD:293786 2/28 (7%)
Ank_2 506..597 CDD:289560 24/90 (27%)
ANK 529..654 CDD:238125 39/126 (31%)
ANK repeat 535..565 CDD:293786 12/29 (41%)
ANK repeat 567..598 CDD:293786 11/30 (37%)
Ank_2 572..661 CDD:289560 29/90 (32%)
ANK repeat 600..630 CDD:293786 11/31 (35%)
ANK repeat 633..662 CDD:293786 9/28 (32%)
ANK 661..785 CDD:238125 6/39 (15%)
ANK repeat 666..697 CDD:293786 4/30 (13%)
Ank_2 672..762 CDD:289560 6/28 (21%)
ANK repeat 699..730 CDD:293786 1/1 (100%)
ANK repeat 732..762 CDD:293786
ZU5 927..1030 CDD:128514
Death_ank 1417..1497 CDD:260029
ER-remodelling 11936..>12013 CDD:258892
pyxNP_612015.1 Ank_4 99..153 CDD:290365 16/53 (30%)
ANK repeat 102..130 CDD:293786 8/27 (30%)
ANK 127..252 CDD:238125 40/125 (32%)
ANK repeat 132..163 CDD:293786 11/30 (37%)
Ank_2 137..226 CDD:289560 27/89 (30%)
ANK repeat 166..196 CDD:293786 9/30 (30%)
ANK 198..319 CDD:238125 45/152 (30%)
ANK repeat 200..229 CDD:293786 10/28 (36%)
Ank_2 203..296 CDD:289560 38/124 (31%)
ANK repeat 231..262 CDD:293786 14/43 (33%)
ANK 268..387 CDD:238125 39/118 (33%)
ANK repeat 268..296 CDD:293786 12/27 (44%)
Ank_2 270..364 CDD:289560 33/93 (35%)
ANK repeat 298..329 CDD:293786 11/30 (37%)
ANK repeat 331..364 CDD:293786 11/32 (34%)
Ank_5 353..404 CDD:290568 14/50 (28%)
ANK repeat 366..396 CDD:293786 9/29 (31%)
Ion_trans 556..734 CDD:278921
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2336
SonicParanoid 00.000 Not matched by this tool.
21.940

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