DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Ank2 and CG3104

DIOPT Version :9

Sequence 1:NP_001189070.1 Gene:Ank2 / 38863 FlyBaseID:FBgn0261788 Length:13559 Species:Drosophila melanogaster
Sequence 2:NP_001259969.1 Gene:CG3104 / 33486 FlyBaseID:FBgn0031473 Length:321 Species:Drosophila melanogaster


Alignment Length:335 Identity:107/335 - (31%)
Similarity:159/335 - (47%) Gaps:42/335 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly   289 MLLERGAPISAKTKNGLAPLHMAA-QGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRV 352
            |.|::..|...:       ||||| :|:.|...|:|...:..||....|..|.|.:||..||...
  Fly     1 MSLKKETPSDVQ-------LHMAAMRGDEVALLRVLDSGKVHVDCKDEDGTTPLILAAAGGHTYC 58

  Fly   353 AKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMN 417
            ...|||:.||.|:|.|.|.|||..|.:...|.||::|::.|||:                     
  Fly    59 VMELLDQGADPNSRRLTGTTPLFFAAQGGHLDVVKILIKAGASV--------------------- 102

  Fly   418 IVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNV 482
                        |.|:..|.|||.:|.:.....|:|.||..||.|:|..:::.||:.|:::.|:.
  Fly   103 ------------DTPSADGGTPLFVACQGGHVKIVRELLDCGANVNAHMKDRATPVFISAQNGHR 155

  Fly   483 DIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGH 547
            .::.||:|.||::|....|..|.|.|||:.|||.:..||::|||.:|.....|.|||...|..||
  Fly   156 TVLSLLIQAGAEIDIKRIDGATPLWIAAQMGQDHICKVLLQNGANVDTVRCDGATPLFKAAHKGH 220

  Fly   548 IKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKN 612
            ..|..:||:...:: .|..||.:.||.|..:.:..|...|:..|:.......:|.|.|.:|.::.
  Fly   221 AAVITVLLKYRPNL-GQLPNGESALHAAAMFGHMTVCKQLVAAGSDVLLKNHDGLTALQLAHQQK 284

  Fly   613 QMDIATTLLE 622
            ...|...|.|
  Fly   285 YTSICDYLQE 294

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ank2NP_001189070.1 ANK repeat 10..41 CDD:293786
Ank_4 11..64 CDD:290365
ANK 38..163 CDD:238125
ANK repeat 43..74 CDD:293786
Ank_2 48..135 CDD:289560
ANK repeat 76..107 CDD:293786
ANK repeat 109..134 CDD:293786
Ank_4 110..163 CDD:290365
Ank_4 172..225 CDD:290365
ANK repeat 175..202 CDD:293786
ANK 199..324 CDD:238125 11/35 (31%)
ANK repeat 204..235 CDD:293786
Ank_2 209..300 CDD:289560 3/10 (30%)
ANK repeat 237..268 CDD:293786
ANK 266..390 CDD:238125 37/101 (37%)
ANK repeat 270..300 CDD:293786 3/10 (30%)
ANK repeat 303..367 CDD:293786 24/64 (38%)
Ank_2 308..399 CDD:289560 38/91 (42%)
ANK 364..489 CDD:238125 35/124 (28%)
ANK repeat 369..400 CDD:293786 12/30 (40%)
ANK repeat 402..433 CDD:293786 1/30 (3%)
Ank_4 403..456 CDD:290365 9/52 (17%)
ANK repeat 435..466 CDD:293786 13/30 (43%)
Ank_2 440..530 CDD:289560 34/89 (38%)
ANK 463..588 CDD:238125 43/124 (35%)
ANK repeat 468..497 CDD:293786 9/28 (32%)
ANK repeat 501..530 CDD:293786 14/28 (50%)
Ank_2 506..597 CDD:289560 32/90 (36%)
ANK 529..654 CDD:238125 27/94 (29%)
ANK repeat 535..565 CDD:293786 10/29 (34%)
ANK repeat 567..598 CDD:293786 8/30 (27%)
Ank_2 572..661 CDD:289560 13/51 (25%)
ANK repeat 600..630 CDD:293786 7/23 (30%)
ANK repeat 633..662 CDD:293786
ANK 661..785 CDD:238125
ANK repeat 666..697 CDD:293786
Ank_2 672..762 CDD:289560
ANK repeat 699..730 CDD:293786
ANK repeat 732..762 CDD:293786
ZU5 927..1030 CDD:128514
Death_ank 1417..1497 CDD:260029
ER-remodelling 11936..>12013 CDD:258892
CG3104NP_001259969.1 Ank_2 <13..72 CDD:289560 24/58 (41%)
ANK repeat 13..40 CDD:293786 11/26 (42%)
ANK 37..162 CDD:238125 48/157 (31%)
ANK repeat 42..73 CDD:293786 13/30 (43%)
Ank_2 47..137 CDD:289560 39/122 (32%)
ANK repeat 75..106 CDD:293786 13/63 (21%)
ANK 103..228 CDD:238125 48/124 (39%)
ANK repeat 108..137 CDD:293786 12/28 (43%)
Ank_2 113..202 CDD:289560 34/88 (39%)
ANK repeat 141..171 CDD:293786 10/29 (34%)
ANK 169..292 CDD:238125 40/123 (33%)
ANK repeat 174..204 CDD:293786 15/29 (52%)
Ank_2 179..270 CDD:289560 32/91 (35%)
ANK repeat 207..237 CDD:293786 10/30 (33%)
ANK repeat 239..270 CDD:293786 8/30 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4177
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - otm3248
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
32.810

Return to query results.
Submit another query.