DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ank2 and Ankdd1b

DIOPT Version :9

Sequence 1:NP_001189070.1 Gene:Ank2 / 38863 FlyBaseID:FBgn0261788 Length:13559 Species:Drosophila melanogaster
Sequence 2:XP_006517744.1 Gene:Ankdd1b / 271144 MGIID:2444730 Length:575 Species:Mus musculus


Alignment Length:510 Identity:126/510 - (24%)
Similarity:190/510 - (37%) Gaps:159/510 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 SFLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGN 78
            ||..||::.||:.:.:..:..::||..|.....|||.|.....:..|..||...|.||.|.|.|.
Mouse    64 SFQNAAKSSNLDLMEKLFEKKVNINAVNNMNRTALHFAVGRNSLSAVDFLLSHKARVDVADKHGL 128

  Fly    79 TALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDG 143
            |.:|:|:.:|..|::.:|::..|....::|.|...|::|||.|:..:|..|:             
Mouse   129 TVIHLAAWSGSFEIMLMLVKAGADQRAKNQEGMNALHLAAQNNNLHIVDYLI------------- 180

  Fly   144 FTPLAVAMQQGHDKVVAVLLESDTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTP 208
                       ||                   ||                               
Mouse   181 -----------HD-------------------LH------------------------------- 184

  Fly   209 LHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLT 273
            ||                   |:|...:....|.|:||:.|...|:..|:....:...|.:||.|
Mouse   185 LH-------------------DLNQPNERGRKPFHLAAERGHVEMIEKLIFLNLHTSEKDKDGNT 230

  Fly   274 PLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYL 338
            .||.||..||...|.:||.:.:.::...:||..|..:|..|.|.:.:|:||...:.|:......:
Mouse   231 ALHLAAMHGHSPAVQVLLTQWSEVNESNENGETPFLLAVVGGHEECSRVLLAGGSDVNIPNKLNV 295

  Fly   339 TALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESG 403
            :||..|...||..:...||..|||...:..:...|||:|...||..||..||      ||     
Mouse   296 SALQTATRNGHTALVNFLLGENADLQQQKESKEPPLHLAVINNRPAVVNSLL------SA----- 349

  Fly   404 LTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARARE 468
                                :||                                   ||...:.
Mouse   350 --------------------RHD-----------------------------------VDVLDQR 359

  Fly   469 QQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIE 523
            :|||||:|:.||||::|..||:.|..:..|.|...|||.:||:.....|..:||:
Mouse   360 RQTPLHVAADLGNVELVETLLKAGCNLKITDKQGKTALAVAARSQHSLVVDMLIK 414

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ank2NP_001189070.1 ANK repeat 10..41 CDD:293786 8/26 (31%)
Ank_4 11..64 CDD:290365 14/49 (29%)
ANK 38..163 CDD:238125 33/124 (27%)
ANK repeat 43..74 CDD:293786 10/30 (33%)
Ank_2 48..135 CDD:289560 28/86 (33%)
ANK repeat 76..107 CDD:293786 8/30 (27%)
ANK repeat 109..134 CDD:293786 8/24 (33%)
Ank_4 110..163 CDD:290365 10/52 (19%)
Ank_4 172..225 CDD:290365 4/52 (8%)
ANK repeat 175..202 CDD:293786 2/26 (8%)
ANK 199..324 CDD:238125 31/124 (25%)
ANK repeat 204..235 CDD:293786 4/30 (13%)
Ank_2 209..300 CDD:289560 24/90 (27%)
ANK repeat 237..268 CDD:293786 7/30 (23%)
ANK 266..390 CDD:238125 41/123 (33%)
ANK repeat 270..300 CDD:293786 12/29 (41%)
ANK repeat 303..367 CDD:293786 20/63 (32%)
Ank_2 308..399 CDD:289560 28/90 (31%)
ANK 364..489 CDD:238125 27/124 (22%)
ANK repeat 369..400 CDD:293786 12/30 (40%)
ANK repeat 402..433 CDD:293786 2/30 (7%)
Ank_4 403..456 CDD:290365 2/52 (4%)
ANK repeat 435..466 CDD:293786 2/30 (7%)
Ank_2 440..530 CDD:289560 26/84 (31%)
ANK 463..588 CDD:238125 25/61 (41%)
ANK repeat 468..497 CDD:293786 14/28 (50%)
ANK repeat 501..530 CDD:293786 8/23 (35%)
Ank_2 506..597 CDD:289560 6/18 (33%)
ANK 529..654 CDD:238125
ANK repeat 535..565 CDD:293786
ANK repeat 567..598 CDD:293786
Ank_2 572..661 CDD:289560
ANK repeat 600..630 CDD:293786
ANK repeat 633..662 CDD:293786
ANK 661..785 CDD:238125
ANK repeat 666..697 CDD:293786
Ank_2 672..762 CDD:289560
ANK repeat 699..730 CDD:293786
ANK repeat 732..762 CDD:293786
ZU5 927..1030 CDD:128514
Death_ank 1417..1497 CDD:260029
ER-remodelling 11936..>12013 CDD:258892
Ankdd1bXP_006517744.1 PHA02876 <63..>413 CDD:165207 124/507 (24%)
ANK repeat 93..124 CDD:293786 10/30 (33%)
ANK repeat 126..157 CDD:293786 8/30 (27%)
ANK repeat 163..192 CDD:293786 15/121 (12%)
ANK repeat 194..225 CDD:293786 7/30 (23%)
ANK repeat 227..258 CDD:293786 12/30 (40%)
ANK repeat 260..291 CDD:293786 10/30 (33%)
ANK repeat 293..321 CDD:293786 10/27 (37%)
ANK repeat 330..357 CDD:293786 16/92 (17%)
ANK repeat 359..390 CDD:293786 14/30 (47%)
DD 466..>508 CDD:387368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4177
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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