Protein Alignment Ank2 and Ank3

DIOPT Version :9

• Sequence 1: NP_001189070.1
• Gene: Ank2 / 38863
• FlyBaseID: FBgn0261788
• Length: 13559
• Species: Drosophila melanogaster
• Sequence 2: XP_036011414.1
• Gene: Ank3 / 11735
• MGIID: 88026
• Length: 4691
• Species: Mus musculus
• Alignment Length: 6011
• Identity: 1660/6011 - (27%)
• Similarity: 2442/6011 - (40%)
• Gaps: 1773/6011 - (29%)

  Fly     8 QGDGNTSFLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDS 72
            :.|.|.|:|||||||:||:.|:::||.:|:|..|.|||||||||||:||:.||||||:|.|.||:
Mouse    38 KSDANASYLRAARAGHLEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDA 102

  Fly    73 ATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQS 137
            |||||||||||||||||.||||:|:.:.|:||.|||||||||||||||||..|||.||.|||:||
Mouse   103 ATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQS 167

  Fly   138 LATEDGFTPLAVAMQQGHDKVVAVLLESDTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTS 202
            |||||||||||||:|||||:||::|||:||:||||||||||||:|||.|||.|||.||.|.||.|
Mouse   168 LATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVES 232

  Fly   203 K--------SGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLE 259
            |        |||||||||:||||.|:|.||:.:.|.|:::|:::|:|||||:|.|..|||.|||:
Mouse   233 KMVVNRATESGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLD 297

  Fly   260 KGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILL 324
            :|..|:||||||||||||.|||||||||:|||:|.|||.:||||||:|||||.||:|::..::||
Mouse   298 RGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLL 362

  Fly   325 YHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELL 389
            .|..|||:||.||||||||||||||.:|||:|||:.|..||:||||||||||||||||::|:|||
Mouse   363 QHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELL 427

  Fly   390 LRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRI 454
            |:|||||.|.|||||||:|||||||.:|||..|:.|.|||:...|||||.||:|||:.|.:::|.
Mouse   428 LKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRY 492

  Fly   455 LLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAA 519
            |:::||||:|:|::.||||||::|||..|||..|||.||..:|.|...||.||:||:||.::|||
Mouse   493 LVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAA 557

  Fly   520 VLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVA 584
            .|:::||:|...|||||||||:.||||.::||.|||||.|..||.||:|:||||||.||:||:||
Mouse   558 FLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVA 622

  Fly   585 LLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEI 649
            ||||::||||||.||||:|||||||:||||||||:||||||.|||.::.|...:||::||||.::
Mouse   623 LLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDM 687

  Fly   650 SNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQAN 714
            .:||:...|.||...|:||||:||.||||.|||||:|...||::|..||.|||||||..|:|...
Mouse   688 VSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIK 752

  Fly   715 MVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYI 779
            :|.||||:.|.|:|.|..|||.|||.|||||.||:|:||::.|:.|..||||.|.|.|||:||||
Mouse   753 IVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIARRLGYI 817

  Fly   780 SVLDSLKTITKEDETAAAPSQAEEKYRVVAPEAMHESF-MSDSE-------------------EE 824
            ||:|:||.:|:|..|.   :...||:::..||.|:|.. |||.|                   ||
Mouse   818 SVVDTLKVVTEEIMTT---TTITEKHKMNVPETMNEVLDMSDDEVRKASAPEKLSDGEYISDGEE 879

  Fly   825 G-----------------GEDNMLSDQPYRYLTVDEMKSLGDDSLPID---------------VT 857
            |                 .||.:..|.. :||...::|.|||||||.:               ::
Mouse   880 GDKCTWFKIPKVQEVLVKSEDAITGDTD-KYLGPQDLKELGDDSLPAEGYVGFSLGARSASPKIS 943

  Fly   858 RDERMDSNRMTQSAEYASGVPPTIGEEVISPHKTQ-------------VYGSSPKATVDGVYIAN 909
            .|.....||.:.:.:      ..:.||::.|.|.|             .:.|....|:|.|.:.:
Mouse   944 SDRSYTLNRSSYARD------SMMIEELLVPSKEQHLTFTREFDSDSLRHYSWAADTLDNVNLVS 1002

  Fly   910 GSGHDE-----PPHVGRKLSWKSFLVSFLVDARGGAMRGCRHSGVRMIIPSRSTCQPTRVTCRYV 969
            ...|..     |.:..|      |||||:||||||:|||.||.|:|:|||.|....|||:|||.|
Mouse  1003 SPVHSGCSSPLPQYDSR------FLVSFMVDARGGSMRGSRHHGMRIIIPPRKCTAPTRITCRLV 1061

  Fly   970 KPQR---------------------------------TMHPPQLMEGEALASRVLELGPCSTKFI 1001
            |..:                                 ..|||.:.|||:|.||:|:|||..||||
Mouse  1062 KRHKLANPPPMVEGEGLASRLVEMGPAGAQFLGKLHLPTHPPPVNEGESLVSRILQLGPQGTKFI 1126

  Fly  1002 GPVVMEVPHFASLRGKEREIIILRSDNGETWREHTIDNSEEIIHDVLQQCFEPEEIAQLEEQAGN 1066
            |||::|:|||.|:||||||:|:|||:|||||:||..|:..|.:.::|...  .||:...||....
Mouse  1127 GPVIVEIPHFGSMRGKERELIVLRSENGETWKEHQFDSKNEDLAELLNGM--DEELDSPEELGTK 1189

  Fly  1067 HVCRFVTYDFPQYFAVVSRIRQEVHAIGPEGGMVSSTVVPQVQAVFPQGALTKKIKVGLQAQPVD 1131
            .:||.:|.||||||||||||:||.:.||||||::|||.||.|||.||:|||||:|:||||||||.
Mouse  1190 RICRIITKDFPQYFAVVSRIKQESNQIGPEGGILSSTTVPLVQASFPEGALTKRIRVGLQAQPVP 1254

  Fly  1132 PDLTAKLLGRGVAVSPIVTVEPRRRKFHKAITLSMPAPKAHSQGMINQYSGN-TPTLRLLCSITG 1195
            .:...|:||.....|||||||||||||||.||:::|.|....:|:.|.|.|: ||.|||||||||
Mouse  1255 EETVKKILGNKATFSPIVTVEPRRRKFHKPITMTIPVPPPSGEGVSNGYKGDATPNLRLLCSITG 1319

  Fly  1196 GPSRAQWEDVTGSTPLTFVNDCVSFTTTVSARFWLMDCRNISDATKMATELYKEVIHVPFIAKFV 1260
            |.|.|||||:||:|||||:.|||||||.|||||||.||..:.:...:|::||:|:|.||::||||
Mouse  1320 GTSPAQWEDITGTTPLTFIKDCVSFTTNVSARFWLADCHQVLETVGLASQLYRELICVPYMAKFV 1384

  Fly  1261 VFAKKVEPFEAKLRVFCMTDDREDKTLEKHELYTEVAKSRDVEVLEGKPQYIEMAGNLVPVTKSG 1325
            ||||..:|.|:.||.|||||||.|||||:.|.:.|||:|:|:|||||||.|::..|||.|:||.|
Mouse  1385 VFAKTNDPVESSLRCFCMTDDRVDKTLEQQENFEEVARSKDIEVLEGKPIYVDCYGNLAPLTKGG 1449

  Fly  1326 DQLQVQFKAFRENRLPFTVRVKDQHADIVGRTLFMKEPKVAKGEPPQQPICILNIVLPEAVIPDS 1390
            .||...|.:|:||||||:::::|...:..||..|:||||..|| .||..:|.|||.||
Mouse  1450 QQLVFNFYSFKENRLPFSIKIRDTSQEPCGRLSFLKEPKTTKG-LPQTAVCNLNITLP------- 1506

  Fly  1391 TTAFSDRVTSAYRTSMFSLSKHQNDHYIGDIRIVDLSNLLGKDWIQLAPEIGINGEEIDEIINQN 1455
                                                                             
Mouse  1507 ----------------------------------------------------------------- 1506

  Fly  1456 TDSIARQAQSMIRLYKDKPNYDILSLETALKNIGRDDIMKKCKSGRLSHSREFDEADLMKNSESV 1520
                                                           :|.:|
Mouse  1507 -----------------------------------------------AHKKE------------- 1511

  Fly  1521 EELVRRESKRIQQINEREEVKYSAEEKEVEESESDEEAAKRTVAERREKIVKRLSIERSIPASTQ 1585
                                         .||:.|:||.|   |:||:.... |::.:.....|:
Mouse  1512 -----------------------------TESDQDDEAEK---ADRRQSFAS-LALRKRYSYLTE 1543

  Fly  1586 KKEITREITEIKRKSLIEDKKAHHESEILMQLPADNVIIKTTTVPDQVIKMKMGKMDSTEVSKSE 1650
            ....|.|.:....:||   ...:.........|..:......|||...
Mouse  1544 PSMKTVERSSGTARSL---PTTYSHKPFFSTRPYQSWTTAPITVPGPA----------------- 1588

  Fly  1651 FDKELTHKFKTSGRSSEEEDQPSYPDQTDKIVQDISAAEKKEKDGVTFSRVTTITRQEARDITED 1715
                     |:...||...:.||....  |.:..:|          |.|.:
Mouse  1589 ---------KSGSLSSSPSNTPSASPL--KSIWSVS----------TPSPI-------------- 1618

  Fly  1716 FLEIEKRSQLPATSTTATVHEKFVEEIKEKTSPLASVPQETVKEVQQVISEVTEIASKKVENIIS 1780
                  :|.|.|::|::      |:.|.:..||:.|.  .||              |..::.::|
Mouse  1619 ------KSTLGASTTSS------VKSISDVASPIRSF--RTV--------------SSPIKTVVS 1655

  Fly  1781 SFESSKSVDATTVLPTQPSVESTKVSETIKNLEDAKAVSAEQVKTVHVVESSSIEETIAEFEAKK 1845
            ....:..|.:.|:.......|:|    .||.|......|:   :|..|..:.|:.|.
Mouse  1656 PSPYNPQVASGTLGRVPTITEAT----PIKGLAPNSTFSS---RTSPVTTAGSLLER-------- 1705

  Fly  1846 VKYDFHGGEPKTQIPKFTRKPSDDSMKPTAAPRATVESETESVLETKAEKPISKIPVKTIPTEAQ 1910
                                 |..:|.|.|:|::.:...:            |.:|.|:|.|.|
Mouse  1706 ---------------------SSITMTPPASPKSNITMYS------------SSLPFKSIITSA- 1736

  Fly  1911 KVSEVDARKITQDFLQGEKLAAEPKPSPAASKIPKVEPRKSVDKQVDRESKILDDVVASTATIMT 1975
                                      :|..|     .|.|||..    .:|...||:::....|.
Mouse  1737 --------------------------TPLIS-----SPLKSVVS----PTKSAADVISTAKATMA 1766

  Fly  1976 AGLGDEQLKDQLVDHSEIIAKSETVAE-------------KVTELLDTFHKIEEKVTKSEKTSEI 2027
            :.| ...|| |:..|:|:...:.:|:.             |.|..|      ::|:  |..|:.:
Mouse  1767 SSL-SSPLK-QMSGHAEVALVNGSVSPLKYPSSSALINGCKATATL------QDKI--STATNAV 1821

  Fly  2028 SSKVEELVKIEEKPLSQVQPKEDKVAEKVAEVIETFHKIEEKITTADARELTRDFLSMEQQNQLP 2092
            ||.|.......||.||                          .|||......|.::|     ..|
Mouse  1822 SSVVSAASDTVEKALS--------------------------TTTAMPFSPLRSYVS-----AAP 1855

  Fly  2093 SMPQAAEKP--------LESSLTSTSASEPESIVTVK--------PSPPASKIPVVEPRKIVFDE 2141
            |..|:...|        |.||:.:|::|...||:||.        |.|...|:|....    |.:
Mouse  1856 SAFQSLRTPSASALYTSLGSSIAATTSSVTSSIITVPVYSVVNVLPEPALKKLPDSNS----FTK 1916

  Fly  2142 STKPLIEPEPVKTTEKKPLNERQLTADFLSMEQQTQLVSEPAKSLVEEVMKSAEQMVEQPKQQKS 2206
            |...|:.|....|||.:|......|:.  .::....|.|...|..|...:.|::::::...:.|
Mouse  1917 SAAALLSPIKTLTTETRPQPHFNRTSS--PVKSSLFLASSALKPSVPSSLSSSQEILKDVAEMK- 1978

  Fly  2207 LNERQLTEDFLLMEQ--QTQLPSDIVKPTDKLIDGIESAAPVGDEASPFHT--PKLTTSVVTQEP 2267
                   ||.:.|..  ||.:|                      |..||.|  |:
Mouse  1979 -------EDLMRMTAILQTDVP----------------------EEKPFQTDLPR---------- 2004

  Fly  2268 QQLASEYDSDTFGKQATIPLGDSKIDQGLIAPVSMEPRKSLTDAEFCKSVGETITKKMSVGVIEI 2332
                                 :.:||       ..||.|              |.:|:...::::
Mouse  2005 ---------------------EGRID-------DEEPFK--------------IVEKVKEDLVKV 2027

  Fly  2333 SDELKK---IESEIPHSQTPPPTPSDNKTDKQNEEPELISLERDYLADTVTTLHTTTESTLERV- 2393
            |:.|||   :|     |:.||.:|..:|.....::....|.|....|......|  ..|..|||
Mouse  2028 SEILKKDVCVE-----SKGPPKSPKSDKGHSPEDDWTEFSSEEIREARQAAASH--APSLPERVH 2085

  Fly  2394 --SAITKIEHFSVHNVKSETFTRT-----------DEPDKLL---------HSVVAPPDIQKLYS 2436
              :.:|::..:..:::.|.:.|..           :|..|.:         |.:..||
Mouse  2086 GKANLTRVIDYLTNDIGSSSLTNLKYKFEEAKKDGEERQKRILKPAMALQEHKLKMPP------- 2143

  Fly  2437 QDTTSFTEMSTSSQTPKMTTTTTMTAQIDRTKVDLTIPGQDQQKQKDLKEQSAVVVDAKAET--E 2499
               .|....::..:..||..:.        ...|..:...|...|.|  :..:.:.|:..||  |
Mouse  2144 ---ASMRPSTSEKELCKMADSF--------FGADAILESPDDFSQHD--QDKSPLSDSGFETRSE 2195

  Fly  2500 KTASDREYLEQIMGCGDVRRKIMRLESSCSTESLESVGKSSTVTPKYIGDNVPV----------V 2554
            ||.|                         :.:|.||.|      ||.:...||:          |
Mouse  2196 KTPS-------------------------APQSAESTG------PKPLFHEVPIPPVITETRTEV 2229

  Fly  2555 REVVQSMEDKICSTVVSAIPFTVQKRKPHDDDKEPNIVELEKQILTPADLALEKIFKCEPPSEVV 2619
            ..|::|.|..     ...||.: |...|......|..:|||.:..|.:.....|.|:.:..||..
Mouse  2230 VHVIRSYEPS-----SGEIPQS-QPEDPVSPKPSPTFMELEPKPTTSSIKEKVKAFQMKASSEEE 2288

  Fly  2620 KISPIEAMSLGLKEIDEEVCEKVCEKRKSFVVAEDLCETEKTLTEQVIDLNRQVDQVPARVFTET 2684
            ..|.:.:..:.:||                       ||..|.|.:::..:....:..:....||
Mouse  2289 DHSRVLSKGMRVKE-----------------------ETHITTTTRMVYHSPPGGECASERIEET 2330

  Fly  2685 IERHLDLEDRDVIEALPKVREVVQDIERKYPAASLEAKPFSPRKRVTPDRKVDVSSLEQQILTDA 2749
            :..|      |:::|....|:         |:..| |..|..:..::||
Mouse  2331 MSVH------DIMKAFQSGRD---------PSKEL-AGLFEHKSAMSPD---------------- 2363

  Fly  2750 DLILDGLGSKCVPEQKVQSPIFSSNKASSSTENLEDICEKKCSKRTISDMTKVF--ERQEDPTTM 2812
                       |.:...::....:.|.|.....||.|.|....|...::.|:|.  |.::.|...
Mouse  2364 -----------VAKSAAETSAQHAEKDSQMKPKLERIIEVHIEKGNQAEPTEVIIRETKKHPEKE 2417

  Fly  2813 PSI--KDVKS---TTAKFLESESGKFAITESIQHFNAKGSINKEVAGIEKGQIRFLKDCDTQEFP 2872
            .|:  ||:..   ....||..:...|...|                  |:||      .:.:|..
Mouse  2418 VSVYQKDLSRGNINLRDFLPEKHDAFPCPE------------------EQGQ------QEEEELA 2458

  Fly  2873 IETNLDTKLVEFPKITHTLERLHSISKTDIADTKKVVHESSEFKSKLDKLVHKTEQTDNQNPDKF 2937
            .|.:|.:.|                             |||...:       ...|.::..|...
Mouse  2459 AEESLPSYL-----------------------------ESSRVNT-------PGSQEEDSRPSSA 2487

  Fly  2938 KFPTQDNFDELQTQKSLTSELVTMTD-------SSEYKFPPEGKSILGKEPIESESDEELDNLNK 2995
            :..:.|::   :|.|.|:...|...|       ...|:|..  |.:|.::...|.||.|
Mouse  2488 QLLSDDSY---KTLKLLSQHSVEYHDDELSDLRGESYRFAE--KMLLSEKLDVSHSDTE------ 2541

  Fly  2996 ICKLQLLSKIEQSSFIDTTEIANTEKREITKFPTTNDSHSDLFSK----------SRATLKTQSG 3050
                   ..:...:...::|:..::||...|..|.  ...::.||          .|.: |.:..
Mouse  2542 -------ESVTDHAGPPSSELQGSDKRSREKVATA--PPKEILSKIYKDVSENGLGRVS-KDEHF 2596

  Fly  3051 EKTHCTHFTETISDKNYNSFSDTSFLLNSVTASADKSPLHPEEKTKSPEKKDEKVLAQPDDNFKS 3115
            ||....|::..:|...:..:..    |:.......:..|..|::.....|:.|:.|.:....|:.
Mouse  2597 EKLTVLHYSGNVSGPKHAMWMH----LSEDRLDRGREKLMYEDRVDRTVKEAEEKLTEVSQFFRD 2657

  Fly  3116 VIETDKPSPKEYSDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPVKIDEEVLAKP 3180
              :|:|     .:||::.|:...:|.:           |.|.|  .......||.|:..|:||
Mouse  2658 --KTEK-----LNDELQSPEKKPRPKN-----------GKDYS--SQSSTSSSPEKVLTELLA-- 2700

  Fly  3181 GGSSKSVVETDKPSPKEYSDDETEDEIDFPKPQDKPFKEATPSVTPVSTIPDVKAIDFVSFKAEE 3245
              |:...|:..:..|...|..:.||.           |..:.|.:|.:.:|..::.|  ....||
Mouse  2701 --SNDEWVKARQRGPDGQSVPQAEDR-----------KAPSRSNSPENRVPTQQSED--DQPPEE 2750

  Fly  3246 CSTTI----------QTNIKLASTSLTTKDTKIVQPIDSLSNLKDDKFPTSVGDKAKSPRESVKP 3300
            ...|:          |:..:|       |.:|       ||::: .||......|:|.|     |
Mouse  2751 AKRTVVAQSRGQEGPQSGFQL-------KQSK-------LSSIR-LKFEQGARAKSKDP-----P 2795

  Fly  3301 NLKEYSDKEEKPDSHPVSLVTSVTGSGDKSPLHP----EEKPKSPEKKDEKILAKPDDSSKSVVK 3361
            :.:::.|   .|...||......     |.|.||    |::.|:.:..:|::   |..:..:|.|
Mouse  2796 HEEKHLD---GPSRIPVKKTQET-----KLPTHPGFAREKQQKAVDPLEERV---PVQNDVTVFK 2849

  Fly  3362 TDKPSPKEYSDDEIEDEIEIPKPLDKPISHPTSLVTSVTGSGDKSPLHPEEKPKSPEKKDEKVLA 3426
            .|.....|                         :|||.:|||
Mouse  2850 ADHAQSNE-------------------------IVTSKSGSG----------------------- 2866

  Fly  3427 KPDDSSKSVVKTDKPSPKEYSDDETED-------EIEIPKPLDKPISHPTSLVTGVTFGGDKSPL 3484
              :..|.......|..|..:.:.:.||       ::|...|.|:.:..     |..:.|.:.:..
Mouse  2867 --NGKSHRTEMLSKAMPDFFPEQQVEDSACPITSDLETKGPWDRKVFR-----TWESSGANNTKA 2924

  Fly  3485 HPEEKLKSPEKKD--EKVLAKPDDSSKSVVK------TDKPSPKEYSDDETE-DEIEIPKPLDKP 3540
            . :|:|......|  |....:||||.....|      |::......:...:| .|:.:..| .|.
Mouse  2925 Q-KEQLSHVLVHDIRENHAGRPDDSENGDPKSGFMYVTEREHKMLTNGSLSEIKEMSVKSP-SKK 2987

  Fly  3541 ISHPTSLVTGVTFGGDKSPLHPEEKLKSPEKKDEKVLAKPDDSSKSVVKTDKPS------PKEYS 3599
            :.:...:|.      |..|  |...|..|.::.|..||    |...:..||:..      |..:.
Mouse  2988 VLYREYIVK------DGDP--PSSALNHPPRRSESSLA----SHIPIRVTDERRMLSSNIPDGFC 3040

  Fly  3600 DDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDGSSKSVV 3664
            :..|..:.|:...:.:|     |:..||.           |........||||      :...:.
Mouse  3041 EQSTFPKQELSPRVSRP-----SMSEGVV-----------ESQHFNSVDDEKV------TYSEIS 3083

  Fly  3665 KTDKPSPKEY-SDDETE-------DEIEIPKPLDKPISHPTSLVTGVTFGGDGSPLHREEKPKSP 3721
            |..|  .:.| :.||||       |.:|.....|.|.|       .|...|....|.:.|..|
Mouse  3084 KVSK--HQSYLALDETETSPTKSPDSLEFSPGKDSPSS-------DVFDHGSVDGLEKTEGGK-- 3137

  Fly  3722 EKKDEKVLAKPDDSSKSVVKTDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLV---TGVTYGG 3783
            |.|...|..       |.|:..|...||..          |..:.|.||.....|   .|..|
Mouse  3138 EIKTLPVYV-------SFVQVGKQYEKELQ----------PGGVKKIISQECKTVQEARGTFY-- 3183

  Fly  3784 DGSPLHPEEKPKSPEKKDE----KVLAKSDDSSKSVVKTDKPSPKEYSDDETEDEIEIPKPLDKP 3844
               ....:::|.||:...|    :.::..|.|.||.:..:.||.:|.|.:.|.
Mouse  3184 ---TARQQKQPPSPQGSPEDDTLEQVSFLDSSGKSPLTPETPSSEEVSYEFTS------------ 3233

  Fly  3845 ISHPTSLVTGVTFGGDGSPLHPEEKPKSPEKKDEKVLAKPDGSSKSVVETDKPSPKEYSDDETED 3909
             ..|.||:..:.  |..||:        ||..:|....:|..:....|..:|.:.::.|.|..:.
Mouse  3234 -KTPDSLIAFIP--GQPSPI--------PEVSEESEEEEPKSAPLRQVTVEKETDRDVSKDSIQR 3287

  Fly  3910 E-------IEIPKPLDKPISHPTSLVTGVTFGGDGSPLHPEEKPK-SPEKK-DEKVLAKPDDSSK 3965
            .       ||.|.|  .|:              |...:..::|.: .||:: |...::..|:|.|
Mouse  3288 PKCNRVAYIEFPPP--PPL--------------DADQMESDKKHQYLPEREVDMMEVSLQDESDK 3336

  Fly  3966 -----SVVKTDKPSP----KEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEK 4021
                 .|::...|||    .|.||...::.:..|.|:.|           .||           |
Mouse  3337 YQLAEPVIRVQPPSPVPPGAEASDSSDDESLYQPVPVKK-----------YTF-----------K 3379

  Fly  4022 LKSPEKKDEKVLAKPDDSSKSVVKTDKPS-PKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTF 4085
            ||..::..:       |::||.....|.| .||...:..|.|    ..||.|
Mouse  3380 LKEVDEGQK-------DTAKSKTAATKASNQKEADGNGREGE----SGLDSP------------- 3420

  Fly  4086 GGDKSPLHPEEKPKSPEKKDEKVLAKPDGSSKSVVETDKPSPKEYSDDETEDEIEIPKPLDKPIS 4150
                                :...|:...:.:||.|....:..|:|.|....||:
Mouse  3421 --------------------QNETAQNGNNDQSVTECSIATTAEFSHDTDATEID---------- 3455

  Fly  4151 HPTSLVTGVTFGGDGSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTD--KPSPKEYSDDE--- 4210
               ||        ||..|..|:...:  :.|.|:.::..|:.|.|....  ||:.:.:|..:
Mouse  3456 ---SL--------DGYDLQDEDDGLT--ESDSKLPSQTIDTKKDVWTEGILKPADRSFSQSKLEV 3507

  Fly  4211 -TEDEIEIPKPLDKPISHPTSLVTGVTFGGDGSPLHPEEKPKSPEKKDEKVLAK--------PDD 4266
             .|:|.::....:||                 ||.......::|||.|.|..|:        ||
Mouse  3508 IEEEEGKVGLDEEKP-----------------SPSKSPSSDRTPEKADPKSGAQFFTLEGRHPD- 3554

  Fly  4267 SSKSVVKTDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEK 4331
              :||:      |..|...:.::|...|        ..|....|:.|           .|....:
Mouse  3555 --RSVL------PDTYFSYKVDEEFATP--------FKTVATKGLDF-----------DPWPNNR 3592

  Fly  4332 KDEKVLAKPDGSSKSVVETDKP---SPKEYSDDETEDEIEIPKPLDK--PISHPTSLVTGVTFGG 4391
            .|.:|.   ||.|:.  :..||   :..:.|...|.|......|.|:  |.|.|...
Mouse  3593 GDNEVF---DGKSRE--DDTKPFGLAVDDRSPATTPDTTPARTPTDESTPTSEPNPF-------- 3644

  Fly  4392 DGSPLHP--------------------EEKPKSPEKKDEKVLAKPGGSSKSVVETDKPSPKEYSD 4436
               |.|.                    ||:.:..:..:.....|.|...:..:.||.|.|:  |.
Mouse  3645 ---PFHEGKMFEMTRSGAIDMSKRDFVEERLQFFQIGEHTPEGKSGAQGEGDMVTDTPQPQ--SG 3704

  Fly  4437 DETEDEIEIPKPLDKPISHPTSLVTGVTFGVDKSPLHPEEKPNSPEKKDEKVLAKPDDSSKSVVK 4501
            |.:.|     ..|::.:..|:         ||.:|    ..|::.|.::....:...:.|.:...
Mouse  3705 DTSVD-----TNLERDVVAPS---------VDPNP----SIPSNGECQEGTACSGSLEKSAAATN 3751

  Fly  4502 TDKPIPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDGSPLHPEEKPKSPEKKDEKVLA 4566
            |.|..||..:            |:...||..|     :|...:||        .....|.|.|:.
Mouse  3752 TSKVDPKSRT------------PIKMGISAST-----MTMKKEGS--------GEVTDKTEAVVT 3791

  Fly  4567 KPDDSSKSVVK--TDKPS------PKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDGSP 4623
            ........:||  :..||      |:|..|.: :|.......||.......:..:.:...|..:.
Mouse  3792 SCQGLENEIVKEISSAPSSQVGIRPQEKHDFQ-KDNFNNNNNLDASTMQTDNSTSHIVLTGRAAS 3855

  Fly  4624 LHPEEKPKSPEKKDEKVLAKPDGSSKSVVETDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLV 4688
            ....|: .:|.|          ||.||      |..:.:|..|:..|
Mouse  3856 TCTTEE-ANPVK----------GSGKS------PGTQGHSSRESRKE------------------ 3885

  Fly  4689 TGVTFGGDGSPLHPEEKPKSPEKKD-EKVLAKPDGSSKSVVETDKPSPKEYSDDETEDEIEIPKP 4752
                      |:....|.|.|.|.. .|.:..|:..:.|  :|.|  |::....|....:.....
Mouse  3886 ----------PIGLRRKSKLPIKATAPKDVFPPNHKADS--KTGK--PRQVGQYEKHKALPTSSC 3936

  Fly  4753 LDK----PI--SHPTSLVT---GVTFGGDGSPLHPEEKPKSPEKKDEKVLAKPGGSSKSVVETDK 4808
            ||.    |:  :|..:||:   .......|.|...:.| :.|.|...||     .|::..|.|..
Mouse  3937 LDAKSRIPVKNTHRENLVSVRKACATQKRGQPERGKAK-QPPSKLPVKV-----RSTRVTVTTTN 3995

  Fly  4809 PSPKEYSDDETEDEIDFPKPQDKPFKEATPSVTPVSTIPDVKAIDFVSFKAEECSTTIQ------ 4867
            .|                        ..|.:.|..:|...||..:  |...|.|...|:
Mouse  3996 TS------------------------TTTTTTTTTTTTTTVKVTE--SQLKEVCKHPIEYFKGIS 4034

  Fly  4868 -TNIKLASTSLTTKDTKIVQPIDSLSNLKDDKFPTSVGDKAKSPRESVKPNLKEYSDKEEKPDSH 4931
             ..:||.. .||.:|.|:      .|.|.|::..||............:|::...|.:.:|.::.
Mouse  4035 GETLKLVD-RLTEEDKKM------QSELSDEEESTSRNTSLSETSRGGQPSVTTKSARNKKTEAP 4092

  Fly  4932 PVSLVTSVTGSGDKSPLHPEEKPKSP-EKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEI 4995
            |:.......||       ....|:|| |:.|.::....|....|..|..:  ...:|.||. ::|
Mouse  4093 PLKSKRGKAGS-------RRTGPQSPCERTDIRMAIVADHLGLSWTELAR--ELNFSVDEI-NQI 4147

  Fly  4996 EIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKLPEKKDEKVLAKPDDSSKSVVKTDKPIPK 5060
            .        :.:|.||:                                   |:|.:...|.:.:
Mouse  4148 R--------VENPNSLI-----------------------------------SQSFMLLKKWVTR 4169

  Fly  5061 EYSDDETD---------DEIDFPKPLDKPISHPTSLVTGVTFGVDKSPLHPEEKPKLPEKKDEKV 5116
            :..:..||         :.||....|:.||....::....:|..:.:..|
Mouse  4170 DGKNATTDALTSVLTKINRIDIVTLLEGPIFDYGNISGTRSFADENNVFH--------------- 4219

  Fly  5117 LAKPDDSSKSV-VKTDKPI------PKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGVDKS 5174
              .|.|...|. |:.:.|:      |..:..|:...:|   ..::.|...|:.|..|:.
Mouse  4220 --DPVDGHPSFQVELETPMGLYCTPPNPFQQDDHFSDI---SSIESPFRTPSRLSDGLV------ 4273

  Fly  5175 PL-----HPEEKPNSPEKKDEKVL-AKPDDSSKSVVKTDKPIPKEYSDDETDDEIEIPKPLDKPI 5233
            |.     ||...|.....:|..:. :|.||   ||..||...|.:.      ||.::........
Mouse  4274 PSQGNIEHPTGGPPVVTAEDTSLEDSKMDD---SVTVTDPADPLDV------DESQLKDLCQSEC 4329

  Fly  5234 SHPTSLVTGV-TFGGDGSPLHP---------EEKPKSPEKKDEKVLAKPDDSSKSV---VKTDKP 5285
            :...:.|.|: ..|....||.|         |::.|.....||:|   .:|..||:   ::.::.
Mouse  4330 AQCWASVPGIPNDGRQAEPLRPQTRKVGMSSEQQEKGKSGPDEEV---TEDKVKSLFEDIQLEEV 4391

  Fly  5286 SPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGG--DGSPLHPEEKPKSPEKKDEKVLAKP 5348
            ..:|.::|:.:..:...:..:..:|         :..|  :.:|....|.|....:....:|.:.
Mouse  4392 EAEEMTEDQGQAMLNRVQRAELAMS---------SLAGWQNETPSGSLESPAQARRLTGGLLDRL 4447

  Fly  5349 DDSSKSVVKTDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDGSPLHPEEKPKSP 5413
            ||||                |:..|.|             ||.:|       |.|...|......
Mouse  4448 DDSS----------------DQARDSI-------------TSYLT-------GEPGKIEANGNHT 4476

  Fly  5414 VKIEEEVLAKP------DDSSKSVVETDKLSPKEYSDDETEDEIE----IPKPLDKPFK----EA 5464
            .::..|..|||      :|..|..:: :.|.||.:....||:.:.    ..|.|::..|    :|
Mouse  4477 AEVIPEAKAKPYFPESQNDIGKQSIK-ENLKPKTHGCGRTEEPVSPLTAYQKSLEETSKLVIEDA 4540

  Fly  5465 MPSVTPVS------TIPDVRAIDVVSFKAEECSTTIQTNIKLASTSITTKDTKIVKPI-----DS 5518
            .....||.      |..|.:|  .::.:.||.||..:..:|....:.|.......|.:     ||
Mouse  4541 PKPCVPVGMKKMTRTTADGKA--RLNLQEEEGSTRSEPKVKSPGEAFTRMTACCYKDLRNSESDS 4603

  Fly  5519 LSNLKDDKFPTSV--------GDKAQS-PRESVKPNLKEYSDKEEKPDSHPVSLVTSVMGSGDKS 5574
             |:.::.:..|.|        |::|:: |.|||..  ::::|:|.       :|:|..:......
Mouse  4604 -SSEEEQRITTRVIRRRVIIKGEEAKNIPGESVTE--EQFTDEEG-------NLITRKITRKVIR 4658

  Fly  5575 PLHPEEKPKSPEKKDEKVLAKPDDSSKSVVK 5605
            .:.|:|: |..:.:.|....|.....::|.|
Mouse  4659 RIGPQER-KQDDVQGEGYKVKTKKEIRNVEK 4688

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ank2	NP_001189070.1	ANK repeat	10..41	CDD:293786	17/30 (57%)
		Ank_4	11..64	CDD:290365	34/52 (65%)
		ANK	38..163	CDD:238125	97/124 (78%)
		ANK repeat	43..74	CDD:293786	23/30 (77%)
		Ank_2	48..135	CDD:289560	67/86 (78%)
		ANK repeat	76..107	CDD:293786	22/30 (73%)
		ANK repeat	109..134	CDD:293786	20/24 (83%)
		Ank_4	110..163	CDD:290365	43/52 (83%)
		Ank_4	172..225	CDD:290365	41/60 (68%)
		ANK repeat	175..202	CDD:293786	20/26 (77%)
		ANK	199..324	CDD:238125	82/132 (62%)
		ANK repeat	204..235	CDD:293786	19/30 (63%)
		Ank_2	209..300	CDD:289560	59/90 (66%)
		ANK repeat	237..268	CDD:293786	17/30 (57%)
		ANK	266..390	CDD:238125	92/123 (75%)
		ANK repeat	270..300	CDD:293786	24/29 (83%)
		ANK repeat	303..367	CDD:293786	42/63 (67%)
		Ank_2	308..399	CDD:289560	64/90 (71%)
		ANK	364..489	CDD:238125	82/124 (66%)
		ANK repeat	369..400	CDD:293786	25/30 (83%)
		ANK repeat	402..433	CDD:293786	20/30 (67%)
		Ank_4	403..456	CDD:290365	31/52 (60%)
		ANK repeat	435..466	CDD:293786	17/30 (57%)
		Ank_2	440..530	CDD:289560	48/89 (54%)
		ANK	463..588	CDD:238125	76/124 (61%)
		ANK repeat	468..497	CDD:293786	17/28 (61%)
		ANK repeat	501..530	CDD:293786	15/28 (54%)
		Ank_2	506..597	CDD:289560	60/90 (67%)
		ANK	529..654	CDD:238125	84/124 (68%)
		ANK repeat	535..565	CDD:293786	20/29 (69%)
		ANK repeat	567..598	CDD:293786	23/30 (77%)
		Ank_2	572..661	CDD:289560	58/88 (66%)
		ANK repeat	600..630	CDD:293786	25/29 (86%)
		ANK repeat	633..662	CDD:293786	11/28 (39%)
		ANK	661..785	CDD:238125	75/123 (61%)
		ANK repeat	666..697	CDD:293786	19/30 (63%)
		Ank_2	672..762	CDD:289560	53/89 (60%)
		ANK repeat	699..730	CDD:293786	17/30 (57%)
		ANK repeat	732..762	CDD:293786	18/29 (62%)
		ZU5	927..1030	CDD:128514	66/135 (49%)
		Death_ank	1417..1497	CDD:260029	0/79 (0%)
		ER-remodelling	11936..>12013	CDD:258892
Ank3	XP_036011414.1	Ank_2	59..>304	CDD:423045	169/244 (69%)
		ANK repeat	73..104	CDD:293786	23/30 (77%)
		ANK repeat	106..137	CDD:293786	22/30 (73%)
		ANK repeat	139..164	CDD:293786	20/24 (83%)
		Ank_2	195..>437	CDD:423045	165/241 (68%)
		ANK repeat	205..240	CDD:293786	22/34 (65%)
		ANK repeat	242..273	CDD:293786	19/30 (63%)
		ANK repeat	275..306	CDD:293786	17/30 (57%)
		ANK repeat	308..333	CDD:293786	21/24 (88%)
		ANK repeat	341..372	CDD:293786	17/30 (57%)
		PHA03095	377..>665	CDD:222980	195/287 (68%)
		ANK repeat	377..405	CDD:293786	20/27 (74%)
		ANK repeat	407..438	CDD:293786	25/30 (83%)
		ANK repeat	440..471	CDD:293786	20/30 (67%)
		ANK repeat	473..504	CDD:293786	17/30 (57%)
		ANK repeat	506..537	CDD:293786	18/30 (60%)
		ANK repeat	539..568	CDD:293786	15/28 (54%)
		Ank_2	559..>796	CDD:423045	148/236 (63%)
		ANK repeat	572..601	CDD:293786	19/28 (68%)
		ANK repeat	605..634	CDD:293786	21/28 (75%)
		ANK repeat	638..669	CDD:293786	26/30 (87%)
		ANK repeat	671..702	CDD:293786	12/30 (40%)
		ANK repeat	704..735	CDD:293786	19/30 (63%)
		ANK repeat	737..768	CDD:293786	17/30 (57%)
		ANK repeat	770..798	CDD:293786	17/27 (63%)
		Ank_4	771..823	CDD:372654	34/51 (67%)
		ZU5	1018..1155	CDD:128514	67/142 (47%)
		UPA_2	1377..1506	CDD:375346	73/129 (57%)
		Herpes_BLLF1	<1542..1949	CDD:282904	115/620 (19%)
		DUF2890	3296..>3412	CDD:314108	35/160 (22%)
		Death_ank3	4113..4196	CDD:176781	19/128 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	274	1.000	Domainoid score	I1769
eggNOG	1	0.900	-	-		E2759_KOG4177
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	1722	1.000	Inparanoid score	I70
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1011028at2759
OrthoFinder	1	1.000	-	-		FOG0000917
OrthoInspector	1	1.000	-	-		otm43456
orthoMCL	1	0.900	-	-		OOG6_100012
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2336
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.800