DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33965 and SFH5

DIOPT Version :9

Sequence 1:	NP_001033983.1	Gene:	CG33965 / 3885668	FlyBaseID:	FBgn0053965	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_012390.1	Gene:	SFH5 / 853296	SGDID:	S000003681	Length:	294	Species:	Saccharomyces cerevisiae

Alignment Length:	254	Identity:	54/254 - (21%)
Similarity:	92/254 - (36%)	Gaps:	64/254 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 FYSLQAVIPEVFNDQRLVDNAQVLEIIRLGVILRIPLDEEDTGPAVTIIRAGSYDINKFKFQDI- 141
            |..|.....||.|          .|:..:| ||....:.:....|||....|.....|..||::
Yeast    89 FNPLSCAYKEVHN----------TELQNVG-ILTFDANGDANKKAVTWNLYGQLVKKKELFQNVD 142

  Fly   142 ----IRVGSMFGEIMMLEDDNASVSGYL-EIMDMSGVT----GANLFALQPQLLSKFSAYADEAM 197
                .|:|.|...:.:| |..:|.:.|: ::.|..||:    .:::......::..|..|..|.:
Yeast   143 KFVRYRIGLMEKGLSLL-DFTSSDNNYMTQVHDYKGVSVWRMDSDIKNCSKTVIGIFQKYYPELL 206

  Fly   198 PTRQKGIHFINVPKAFETGFKSLLGWFPGKIKERVSVSSDPEAIFERVPKHYLPEEYGGSKGTMK 262
            ..:    :|:|||..|        ||....||:.|.         |...|.::....|...|
Yeast   207 YAK----YFVNVPTVF--------GWVYDLIKKFVD---------ETTRKKFVVLTDGSKLG--- 247

  Fly   263 DITDQMEAKLCSYRSYFEDCQH--FGAHDKLRE--EASVLNPDESHFGVDGSFRQLVID 317
                          .|.:||.:  :|..||...  :.:|.|...:.:|:....:|::.|
Yeast   248 --------------QYLKDCPYEGYGGKDKKNNLTKQNVTNVHPTEYGLYILQKQIIED 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33965	NP_001033983.1	CRAL_TRIO_N	32..77	CDD:215024
CG33965	NP_001033983.1	SEC14	101..256	CDD:238099	36/164 (22%)
SFH5	NP_012390.1	SEC14	101..263	CDD:214706	43/211 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900