DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33965 and Clvs1

DIOPT Version :9

Sequence 1:	NP_001033983.1	Gene:	CG33965 / 3885668	FlyBaseID:	FBgn0053965	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_001342112.1	Gene:	Clvs1 / 74438	MGIID:	1921688	Length:	354	Species:	Mus musculus

Alignment Length:	292	Identity:	66/292 - (22%)
Similarity:	137/292 - (46%)	Gaps:	30/292 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SGSSPNSIRPLPPGLQKVAIEELNEVPSRVESDIAALKEWLQKQPHL-CACLEDQFLLSFLRGSK 65
            :|.||::|       :|..: ||||.|..:..||..:::.:..:|.: ....:|.|:|.|||..|
Mouse    28 AGLSPDTI-------EKARL-ELNENPDILHQDIQQVRDMIITRPDIGFLRTDDAFILRFLRARK 84

  Fly    66 FSLEKAKQKIDRFYSLQAVIPEVFNDQRLVDNAQVLEIIRLGVILRIP--LDEED-TGPAVTIIR 127
            |....|.:.:.:::..:.:..::|.:.:..|..     |:..:|...|  |:..| .|..:.::.
Mouse    85 FHQADAFRLLAQYFQYRQLNLDMFKNFKADDPG-----IKRALIDGFPGVLENRDHYGRKILLLF 144

  Fly   128 AGSYDINKFKFQDIIRVGSMFGEIMMLEDDNASVSGYLEIMDMSGVTGANLFALQPQLLSKFSAY 192
            |.::|.::..|.||:|...:..|: ::||....::|::.|:|.|..:......|.|.:|......
Mouse   145 AANWDQSRNSFTDILRAILLSLEV-LIEDPELQINGFILIIDWSNFSFKQASKLTPSILKLAIEG 208

  Fly   193 ADEAMPTRQKGIHFINVPKAFETGFKSLLGWFPGKIKERVSV-SSDPEAIFERVPKHYLPEEYGG 256
            ..::.|.|..|:||:|.|......:..:..:...|.::|:.: .::..::.:.:...:||.|:||
Mouse   209 LQDSFPARFGGVHFVNQPWYIHALYTLIKPFLKDKTRKRIFLHGNNLNSLHQLIHPEFLPSEFGG 273

  Fly   257 S-----KGTM------KDITDQMEAKLCSYRS 277
            :     .||.      .|.:|:.:....||.:
Mouse   274 TLPPYDMGTWARTLLGPDYSDENDYTHTSYNA 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33965	NP_001033983.1	CRAL_TRIO_N	32..77	CDD:215024	12/45 (27%)
CG33965	NP_001033983.1	SEC14	101..256	CDD:238099	34/158 (22%)
Clvs1	NP_001342112.1	CRAL_TRIO_N	51..97	CDD:215024	12/45 (27%)
		CRAL_TRIO	125..274	CDD:366224	33/149 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	317..354
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835971
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559280at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X106
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.750