Protein Alignment CG33965 and TTPA

DIOPT Version :9

• Sequence 1: NP_001033983.1
• Gene: CG33965 / 3885668
• FlyBaseID: FBgn0053965
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_000361.1
• Gene: TTPA / 7274
• HGNCID: 12404
• Length: 278
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 72/260 - (27%)
• Similarity: 125/260 - (48%)
• Gaps: 17/260 - (6%)

  Fly    17 QKVAIEELNEVPSR---VESDIAALKEWLQKQ--PHLCACLEDQFLLSFLRGSKFSLEKAKQKID 76
            |..|..:||.:|..   ::..:|||:...::.  |.....|.|.|||.|||...|.|:.|.:.:.
Human     7 QPSAGPQLNALPDHSPLLQPGLAALRRRAREAGVPLAPLPLTDSFLLRFLRARDFDLDLAWRLLK 71

  Fly    77 RFYSLQAVIPEVFNDQRLVDNAQVLEIIRLGV--ILRIPLDEEDTGPAVTIIRAGSYDINKFKFQ 139
            .:|..:|..||:..|   :....::.:::.|.  :||   ..:.||..|.|.|...:|...|...
Human    72 NYYKWRAECPEISAD---LHPRSIIGLLKAGYHGVLR---SRDPTGSKVLIYRIAHWDPKVFTAY 130

  Fly   140 DIIRVGSMFGEIMMLEDDNASVSGYLEIMDMSGVTGANLFALQPQLLSKFSAYADEAMPTRQKGI 204
            |:.||..:..|:::.|.:... :|...|.|:.|...::.|.:.|.:..|.:|...::.|.:.:||
Human   131 DVFRVSLITSELIVQEVETQR-NGIKAIFDLEGWQFSHAFQITPSVAKKIAAVLTDSFPLKVRGI 194

  Fly   205 HFINVPKAFETGFKSLLGWFPGKIKERVSVSSD--PEAIFERVPKHYLPEEYGGSKGTMKDITDQ 267
            |.||.|..|...|..:..:...|||||:.:..:  .:::.:..| ..||.||||.:.:|:||..:
Human   195 HLINEPVIFHAVFSMIKPFLTEKIKERIHMHGNNYKQSLLQHFP-DILPLEYGGEEFSMEDICQE 258

  Fly   268  267
            Human   259  258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33965	NP_001033983.1	CRAL_TRIO_N	32..77	CDD:215024	15/46 (33%)
		SEC14	101..256	CDD:238099	42/158 (27%)
TTPA	NP_000361.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		5/12 (42%)
		CRAL_TRIO_N	<40..73	CDD:215024	12/32 (38%)
		CRAL_TRIO	99..248	CDD:395525	43/153 (28%)
		Phosphatidylinositol 3,4-bisphosphate binding. /evidence=ECO:0000250|UniProtKB:Q8BWP5	190..192		0/1 (0%)
		Phosphatidylinositol 4,5-bisphosphate binding. /evidence=ECO:0000250|UniProtKB:Q8BWP5	208..211		0/2 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559280at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10174
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920