DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33965 and Sec14l2

DIOPT Version :9

Sequence 1:	NP_001033983.1	Gene:	CG33965 / 3885668	FlyBaseID:	FBgn0053965	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_653103.1	Gene:	Sec14l2 / 67815	MGIID:	1915065	Length:	403	Species:	Mus musculus

Alignment Length:	296	Identity:	65/296 - (21%)
Similarity:	116/296 - (39%)	Gaps:	48/296 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 LNEVPSRVESDIAALKEWLQKQPHLCACLEDQFLLSFLRGSKFSLEKA-----------KQK-ID 76
            :.::..:.|..:|..:|.:|.........:|.|||.:||...|.|:|:           ||| ||
Mouse     5 VGDLSPKQEEALAKFRENVQDVLPTLPNPDDYFLLRWLRARSFDLQKSEAMLRKHVEFRKQKDID 69

  Fly    77 RFYSLQAVIPEVFNDQRLVDNAQVLEIIRLGVIL-RIPLDEEDTGPAVT---IIRAGSYDINKFK 137
            :..|.|.  |||..        |.|...|.|..| ..|:..:..||...   :..|...|:.:.|
Mouse    70 KIISWQP--PEVIQ--------QYLSGGRCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDLLRTK 124

  Fly   138 FQDIIRVGSMFGEIMMLE--DDNASVSGYLE----IMDMSGVTGANLFALQPQLLSKFSAYADEA 196
            .:|.        |:::.|  .....:...:|    |.|..|:...:|:....:...:|....:|.
Mouse   125 MRDC--------ELLLQECIQQTTKLGKKIETITMIYDCEGLGLKHLWKPAVEAYGEFLTMFEEN 181

  Fly   197 MPTRQKGIHFINVPKAFETGFKSLLGWFPGKIKERVSV--SSDPEAIFERVPKHYLPEEYGGSKG 259
            .|...|.:..:..||.|...:..:..:.....:.::.|  ::..|.:.:.:....||.|||   |
Mouse   182 YPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRRKIMVLGANWKEVLLKHISPDQLPVEYG---G 243

  Fly   260 TMKDITDQMEAKLCSYRSYFEDC-QHFGAHDKLREE 294
            ||.|.....:.|  |..:|..|. :.:...|:::::
Mouse   244 TMTDPDGNPKCK--SKINYGGDIPKQYYVRDQVKQQ 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33965	NP_001033983.1	CRAL_TRIO_N	32..77	CDD:215024	17/56 (30%)
CG33965	NP_001033983.1	SEC14	101..256	CDD:238099	31/166 (19%)
Sec14l2	NP_653103.1	CRAL_TRIO_N	13..59	CDD:215024	13/45 (29%)
		SEC14	76..244	CDD:214706	36/188 (19%)
		GOLD_2	300..381	CDD:290608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810