DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33965 and sec14l5

DIOPT Version :9

Sequence 1:	NP_001033983.1	Gene:	CG33965 / 3885668	FlyBaseID:	FBgn0053965	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	XP_031749906.1	Gene:	sec14l5 / 493292	XenbaseID:	XB-GENE-953433	Length:	793	Species:	Xenopus tropicalis

Alignment Length:	314	Identity:	58/314 - (18%)
Similarity:	117/314 - (37%)	Gaps:	77/314 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SGSSPNSIRPLPPGLQKVAIEELNEVP-SRVESD----------------IAALKEWLQKQPHLC 49
            |...|:|...||.. ...|..||:..| .::::|                :..|::||| :.|..
Frog   210 SADGPSSKDGLPSS-PTAATHELSSTPDDKLDADYIKRYLGDLTPLQESCLIRLRQWLQ-ETHKG 272

  Fly    50 ACLEDQFLLSFLRGSKFSLEKAKQ------------KIDRFYSLQAVIPEVFND---------QR 93
            ...:|:.:|.|||...|:::||::            .:|...|.... |:|.:|         .|
Frog   273 KIPKDEHILRFLRARDFNIDKAREILCQSLTWRKQHHVDYLLSTWDP-PQVLHDYYAGGWHHHDR 336

  Fly    94 LVDNAQVLEIIRLGVILRIPLDEEDTGPAVTIIRAGS-----YDINKFKFQDIIRVGSMFGEIMM 153
               :.:.|.::|||        :.||...|..:...|     ..||:...:......::||.
Frog   337 ---DGRPLYVLRLG--------QMDTKGLVRALGEESLLRHVLSINEEGLRRCEENTNIFGR--- 387

  Fly   154 LEDDNASVSGYLEIMDMSGVTGANLFALQPQLLSKFSAYADEAMPTRQKGIHFINVPKAFETGFK 218
                  .:|.:..::|:.|:...:|:....:.|.:.....:...|.....:..:..|:.|...:.
Frog   388 ------PISSWTCLVDLEGLNMRHLWRPGVKALLRIIEVVEANYPETLGRLLILRAPRVFPVLWT 446

  Fly   219 SLLGWFPGKIKER--VSVSSD---PEAIFERVPKHYLPEEYGG------SKGTM 261
            .:..:.....:::  :...:|   |..:.:.:.|..:|:..||      |:|.|
Frog   447 LVSPFIDENTRKKFLIYAGNDYQGPGGLIDYIDKEVIPDFLGGECMCEVSEGGM 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33965	NP_001033983.1	CRAL_TRIO_N	32..77	CDD:215024	14/72 (19%)
CG33965	NP_001033983.1	SEC14	101..256	CDD:238099	24/164 (15%)
sec14l5	XP_031749906.1	PRELI	17..173	CDD:398400
		CRAL_TRIO_N	256..301	CDD:215024	13/45 (29%)
		CRAL_TRIO	326..490	CDD:395525	26/183 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910